Hey Ruth! If there are absolutely no signs of bed bugs (upon close inspection), its unlikely that they are the cause for the bite marks. I recommend taking another look for dark brown marks (dried blood) and other signs of their presence. Regardless, if you want to kill any bug on that mattress, just get a handheld steamer and blast it. The heat will kill everything and its completely natural. Hope that helps!
Bed bugs are very resilient. Nymphs and adults can persist months without feeding which is unusual for most insects. The ability to survive without a blood meal is longer at cooler temperatures ― potentially up to a year or longer at 55°F or less. In temperature-controlled buildings, a more typical duration is about 2 to 6 months. Consequently, it is usually impractical to leave buildings unoccupied in hopes of ‘starving out’ an infestation. When infested dwellings such as apartments are vacated, bed bugs often disperse to nearby units, or reduce their activity until the unit is reoccupied. 
Bedbug bites don’t normally require treatment by a doctor, though there are a few precautions you should take at home. (8) Start by cleaning the area with soap and water to lower your risk of infection and to relieve itchiness. If the bites are itchy, pick up a corticosteroid cream at your local drugstore and apply it to the area. The bites generally will heal within a couple of weeks. (9)
All these bed bugs can be dealt with. it is best to use a non chemical treatment to make it safe for your environment . here is one i found, food grade Diatomaceous Earth found at garden centers, follow instructions, and move beds away from the walls, sprinkle in the carpet deeply, on to base boards , ( it works like borax powder for fleas and roaches) .

Just came back from a hotel stay, have one VERY itchy bite on my wrist. I don’t know for sure that it is a bed bug bite butI haven’t unpacked my bags yet, so hopefully everything is safe. Right now I have an aloe and lidocaine gel over the bite, but when I get home I may try soaking it in tea bath. the tannin in black tea can also help with itching and swelling.

Bedbugs reproduce by a gruesome strategy appropriately named "traumatic insemination," in which the male stabs the female's abdomen and injects sperm into the wound. During their life cycle, females can lay more than 200 eggs, which hatch and go through five immature "nymph" stages before reaching their adult form, molting after each phase. [Infographic: Bedbugs: The Life of a Mini-Monster]
Bed bugs are a growing problem in schools and daycares. Typically they are introduced by students or staff living with an infestation at home. Pinpointing where the bugs exist can be challenging in such environments since there are no beds or sleeping areas for the insects to congregate. (Similar challenges occur when bed bugs are found in offices, libraries and retail stores.) Usually only small numbers of bed bugs are spotted, often on a student’s clothing, backpack, chair or desk. While this does not necessarily confirm that the child’s residence also has bed bugs, the parents should be notified that the home should be inspected, preferably by a professional. Teachers, nurses, and staff should be educated about the bugs and what they look like. Bed bugs should also be considered if a student frequently has reddened itchy welts --but keep in mind such reactions can be for reasons other than bed bugs. 
Bed bugs are small, brownish, flattened insects that feed solely on the blood of animals. Although the common bed bug (Cimex lectularius) prefers feeding on humans, it will also bite other warm-blooded animals, including dogs, cats, birds and rodents. It has done so since ancient times; bed bugs are mentioned in medieval European texts and classical Greek writings back to the time of Aristotle.
The first thing is you have to be able to recognize and distinguish a bed bug from any other insect. Everything starts to look like a bed bug if you start to worry about them. An adult bed bug is about the size and shape of an apple seed. If it has not fed recently it will be flattened and brown. If it has fed it will be round in circumference and reddish. Immature bed bugs have a similar appearance to adults, with the smallest being the size of the head of a pin. You can then learn to look for their fecal spots, which can be easier to detect than the bugs themselves. Check your hotel rooms when you travel. And think twice before bringing home used furniture. If you are purchasing used furniture, ask the furniture store how they deal with bed bugs. If they have no plan whatsoever, that's probably not a good sign. If you purchase used clothing, put it through a clothes dryer on a medium to high setting for a cycle as soon as you bring it home. And before you move into an apartment, ask the landlord whether there has been a bed bug infestation, or whether the building has ever been treated for bed bugs.

I am 59 and never had any allergies before.. My other half never got bit until recently, and it is only recently I’ve seen the bugs.. we got a new kittie and he gets them before or after they get me. That’s how I finale got to see one, he woke me up chasing it..the bites I cover with alcohol for 2-3 days, the itching stays down… am going to try the Diatomaceous earth trick, am on a small pension and can not afford Orkin or any others..love this site, great information..

Bed bugs infestations can be treated by pesticides (make sure it specifically treats for bed bugs) or call a professional. Clean laundry and bedding by washing in hot water and drying with high heat. Steam cleaning can be effective, but be sure to check for bugs in a week or two. Concentrate in the areas they like to hide such as the seams. Bed bugs are sensitive to heat, so putting your mattress in a tight plastic bag and leaving it in the heat for several days can kill adults and the eggs. Vacuum your mattress and the areas around it. Be sure to immediately empty the vacuum cleaner and throw it out. If your mattress is infested, you may also consider getting a new mattress, but be sure to take care of the rest of your home so that your new mattress doesn’t get infested.
Bedbug bite reactions are self-limited and typically resolve within one to two weeks without intervention.15 There is no evidence that any treatment alters the natural history of bedbug dermatitis.8 If pruritus is present, nonprescription topical antipruritic preparations containing the active ingredient doxepin, or intermediate potency corticosteroids may be beneficial. Mupirocin (Bactroban) and/or systemic antibiotics should be considered in the treatment of superinfected bites.8
Some patients develop blisters filled with blood or bloody fluid, especially on the arms and legs. These blood blisters are extremely rare and can burst, causing bleeding or oozing of the bloody fluid. Healthcare providers are not sure if the cause of these blisters is related to the bug or the human but have found groups of patients that were all bitten by bugs on the same train exhibiting this sign.

Bedbugs reproduce by a gruesome strategy appropriately named "traumatic insemination," in which the male stabs the female's abdomen and injects sperm into the wound. During their life cycle, females can lay more than 200 eggs, which hatch and go through five immature "nymph" stages before reaching their adult form, molting after each phase. [Infographic: Bedbugs: The Life of a Mini-Monster]

Within 20 of exposure I started coming down with bumps. They started to.on my forearms but now have spread to legs. My company sent a exterminator to my home to check to make sure I didn’t spread them to my home, my home declared bug free:). They sent me to employee health where I was put on strong antibiotic and cortisone like cream to put on wounds. They are red, cluster like itchy. Frustrating thing is I keep getting more. I am so itchy I can’t sleep. Could it be something different then bugs that I was exposed to? Just frustrated with continual bites


Very worry about my daughter.Wnt on a trip to Georgia and south Carolina 13 days ago.As soon and we came back started having rash wrist and forearmas.Vry itchy.Have been extending to legs ,shoulder bladdes and upper arms.Doctors not sure if a bed bus bite or scabies.My grandsone have a few bites but it seems to get better.Thest rest of the group seems to be ok.
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Flea bites are caused by the parasitic insect, the flea. The most common species of flea in the US is the cat flea, Ctenocephalides felis. Signs and symptoms of flea bites in humans include itching, hives, a rash with bumps, red spots with a "halo," and swelling around the bite. Treatment for flea bites includes over-the-counter medicine and natural and home remedies to relieve and soothe itching and inflammation. The redness of a flea bite can last from a few hours to a several days.
I was at a friend’s house in the afternoon for 3.5 hrs and woke up at 3 am with severe itching, and pain, on my back. My entire back was covered in bites/rashes, clear lines and clusters. I had no idea what it was and went to the doc. Someone suggested shingles. Doc said definitely bug bites. I talked to my friend and they admitted to having seen bed bugs on the couch “recently.” Freaking out I flipped over my entire bedroom, found nothing. Washed the clothes I wore in hot water and high heat drier. I am hoping that the feeding occured during those few hours and no buggs travelled with me. All I had was me, no stuff. Can they “migrate” on people?

The bites usually last about 7 days, even if they are treated correctly. However, if you have sensitive skin like myself, they can last a couple weeks or in my husbands case, they last only a few days. As mentioned, if you scratch the bites its going to make things worse and besides running the risk of a bacterial infection, they will also take longer to heal so keep your nails away from them!
2. Active Guard Liners: Active Guard Mattress Liners may be placed on beds and are effective as both preventative and active bed bug treatments. They kill bed bugs and dust mites within 72 hours and will prevent bed bugs from infesting mattresses. ActiveGuard Liners act like a fitted sheet; it comes in single, full, queen, and king sizes that fit up to 17" in depth.
Bedbug bites don’t normally require treatment by a doctor, though there are a few precautions you should take at home. (8) Start by cleaning the area with soap and water to lower your risk of infection and to relieve itchiness. If the bites are itchy, pick up a corticosteroid cream at your local drugstore and apply it to the area. The bites generally will heal within a couple of weeks. (9)
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