Bed bug incidents in schools are best handled by knowledgeable pest control firms. Widespread insecticide treatment of classrooms, hallways, buses, etc. is unnecessary, ineffective and imprudent. Effort instead should be spent checking chairs, desks, lockers, coat rooms, etc. in the vicinity of where the bugs were found, and treatment should be focused on those specific areas. Canine inspections can also be useful in finding small numbers of bed bugs in schools and other establishments where there are no beds.      
Just recently had my first experience w/ bedbug bites in Nicaragua. Hundred plus bites in one night and over a period of three days they became so inflamed, there were tiny blisters on each bite. These suckers snacked on me like I was an all you can eat buffet. I itched 4 days straight and finally went to a pharmacy there, which prescribed me acne creme. Worked, I guess, at least psychologically. But the bites kept festering more and more.
Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 

One bed bug will usually take more than one bite. Once a bed bug inserts its mouthparts and finds a suitable blood vessel, it will begin feeding. However, finding the right blood vessel may take more than one injection into the skin. In addition, bed bugs are very sensitive to movement by the host they are feeding on. Therefore, if a sleeping person moves, a feeding bed bug will probably withdraw its mouthparts and begin its search for a blood meal on another part of the body. It’s important to remember that the number of bites a person receives is not indicative of the number of bed bugs that feed on that person.

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