Went on vacation with my husband, just 3 weeks ago. Stayed at a motel in Daytona. Had a double bed. Slept with my husband the first night, we did not go under the cover. The next night slept in the other bed, went under the cover and low and behold felt something biting me in the middle of the night, so I went on top of the cover for the rest of the night. Told my husband about it when we awoke.
Becoming a victim of a bed bug infestation is certainly devastating, but the public can rest easy knowing that these pests are not known to transmit any diseases. While it is true that some pathogens have been detected in and on bed bugs including hepatitis B, and exotic organisms such as Trypanosoma cruzi (cause of Chagas Disease, rarely found in the United States) or Wolbachia species, unlike mosquitoes and ticks, bed bugs have not been associated with disease transmission.
These nocturnal creatures can hide in beds, floors, furniture, wood, and paper trash during the day. We humans usually become their dinner during the night, with peak biting activity just before dawn.They can obtain their meal in as little as three minutes, after which they are engorged and drop off the host, then crawl into a hiding place to digest their meal. Bedbugs can live for 10 months, and can go weeks without feeding.
Traditional methods of repelling and/or killing bed bugs include the use of plants, fungi, and insects (or their extracts), such as black pepper;[54] black cohosh (Actaea racemosa); Pseudarthria hookeri; Laggera alata (Chinese yángmáo cǎo | 羊毛草);[15] Eucalyptus saligna oil;[55][56] henna (Lawsonia inermis or camphire);[57] "infused oil of Melolontha vulgaris" (presumably cockchafer); fly agaric (Amanita muscaria); tobacco; "heated oil of Terebinthina" (i.e. true turpentine); wild mint (Mentha arvensis); narrow-leaved pepperwort (Lepidium ruderale); Myrica spp. (e.g. bayberry); Robert geranium (Geranium robertianum); bugbane (Cimicifuga spp.); "herb and seeds of Cannabis"; "opulus" berries (possibly maple or European cranberrybush); masked hunter bugs (Reduvius personatus), "and many others".[58]
As mentioned earlier, applying insect repellent at bedtime will probably not deter bed bugs from biting. When working in severely infested dwellings, there may be some benefit to spraying tops and bottoms of shoes with DEET-based repellents. Those working in bed bug-infested environments may also want to hot wash or run clothing, etc. through a dryer upon returning home or to the office.    
Hello all I just want to put this out there that heat is the best way to kill these little pests. I work for a company that uses heat to do structural pasteurization, in other words we heat the entire house up to 140°+ (which is higher than the the thermal kill point for bedbugs) for an hour or more (though they can only withstand that heat for less than 15 min) This has been the ONLY way to kill them with a 100% success rate since they are becoming resistant to chemicals and DDT is illegal. Some things work for some infestations but not for all, there are a lot of good ideas on here :-)

Probably chiggers -- they are very small, red mites that usually cannot be seen with the naked eye. They are about as small as the period at the end of this sentence. To stop the itching, use OraJel (usually sold for teething babies), which contains benzocaine (an anesthetic). Also, rub in hydrocortisone cream. To prevent chigger bites, wear long pants and stuff the cuffs into your socks.
Every morning, even after countless treatments of our bed and linens, I wake up with 20-30 new bites. I react extremely strongly to them, they can swell as big as a half dollar, and they itch sO badly I often end up ripping them open, leaving them prone to infection. I’m now a diagnoses anemic, which the doctor is sure is because of the number of bites…they are literally eating me alive…and killing me.
Just because you can't see bed bugs, does not mean that they are not still there. Bed bugs are rarely seen in the day, out in the open or on the surface of beds or chairs. They have been described as champions of hide-and-seek. So, it is not uncommon to miss the bed bugs altogether. Bed bugs love to hide in the cracks and crevices associated with mattresses, cushions, bed frames and other structures, which is why it is very important to look for telltale symptoms of bed bugs and signs of an infestation, such as shed skins and specks of blood or feces on linens, furniture, mattresses and other areas where the bugs might be hiding.
Quote: Similarly, bed bugs will perish in extremely cold temperatures. If it is possible to keep a room unheated for a prolonged period of time, it may kill the population. All stages of the common bed bug, from nymphs to adults, can survive for up to five days in temperatures of fourteen degrees Fahrenheit. Prolonged exposure, however, to these temperatures, will kill them.
First, make sure that the suspected bugs are bedbugs, because other insects or arthropods such as a carpet beetle, scabies mite, a bat bug, louse, or other bugs may be mistaken for bedbugs. If there is confirmation of a bedbug infestation, several measures can be taken to help control or eradicate the infestation, using both nonchemical and chemical (insecticides) methods. It can take several weeks to months to achieve complete eradication of a bedbug infestation, and it may take several treatment cycles to completely eliminate them. In many cases, it will be necessary to hire a pest control service in order to implement a comprehensive extermination strategy.
I was in europe and have always been healthy and felt fine the 2 months while there, on my drive back home I started itching my arm and didn’t think much of it. During the next few days to weeks the itching turned into welts that itched like crazy and got bigger and harder within hours. The redness would then extend out apx. the size of a 50 cent piece that would form a small scab in the middle as it would heal. Then it would heal , but the next few welts would appear in different places. They would start off as itchy flat red circles that would quickly become firm and red. I sometimes would also feel stings all over . I’ve had this problem now for over a month. One dr. told me I had mites, another said I had bed bugs. I have small scars all over my body now. I used the all over cream 4 nights ago that is supposed to kill mites. The itching is still there but not quite as bad today and yesterday. I’ m going for a third opinion tomorrow. I never knew that itching can keep me from working or actually doing anything else except for keeping calamine lotion beside me and rubbing it on me every 10 minutes. Good luck to all of you that are dealing with the same nightmare.
Bedbugs are found all over the world. Bed bug infestations were common in the U.S. before World War II and became rare after widespread use of the insecticide DDT for pest control began in the 1940s and 1950s. They remained prevalent in other areas of the world and, in recent years, have been increasingly observed again in the U.S. Increases in immigration and travel from the developing world as well as restrictions on the use of stronger pesticides may be factors that have led to the relatively recent increase in bedbug infestations. While bedbug infestations are often reported to be found when sanitation conditions are poor or when birds or mammals (particularly bats) are nesting on or near a home, bedbugs can also live and thrive in clean environments. Crowded living quarters also facilitate the spread of bedbug infestations.
While you are sleeping, bed bugs will bite using their mouthparts, commonly referred to as beaks. As they bite, they release an anticoagulant in their saliva preventing your blood from clotting. This allows them to receive a steady two- to three-minute blood meal—what they need in order to survive and reproduce. Bed bugs will not bite in defense, they will only bite for the sole purpose of feeding.
Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 
One trick to make this disposal easier involves using the cut-off end of a nylon stocking (or a knee-high nylon stocking) and a rubber band. Insert the stocking (toe first) into the end of the vacuum suction wand/tube, leaving the opening of the stocking protruding out of the end of the suction wand. Then fold the stocking opening back over the end of the wand and use the rubber band to secure it there. When the vacuum is turned on and the bed bugs are sucked into the tube, they will be trapped in the stocking. Afterwards, carefully remove the rubber band and retrieve the bug-filled stocking. Then secure the end of the stocking with the rubber band and dispose of it. 

I can’t wear any of my rings because my fingers have gotten swollen and they hurt. My wrists have become somewhat painful as well. I get blood blisters that hurt like anything. Those are the worst. I’m living on benadryl and calamine lotion. The calamine seems to be helping to dry them out at least. My right hand is a disaster. Especially on the skin between thumb and forefinger. I look like I’m a leper or something.

I need some really serious advice. I’m presently staying in a shelter because of abusive situation. It’s only been two days but I am COVERED in bed bug bites. The shelter refuses to move me to another bed because of limited space they said. I have taken oral and topical medications. The thing is it keeps getting worse and worse because every night I have to sleep in the same bed.
Probably chiggers -- they are very small, red mites that usually cannot be seen with the naked eye. They are about as small as the period at the end of this sentence. To stop the itching, use OraJel (usually sold for teething babies), which contains benzocaine (an anesthetic). Also, rub in hydrocortisone cream. To prevent chigger bites, wear long pants and stuff the cuffs into your socks.

Bed bugs are attracted to their hosts primarily by carbon dioxide, secondarily by warmth, and also by certain chemicals.[4][16][17][18] Cimex lectularius only feeds every five to seven days, which suggests that it does not spend the majority of its life searching for a host. When a bed bug is starved, it leaves its shelter and searches for a host. It returns to its shelter after successful feeding or if it encounters exposure to light.[19] Cimex lectularius aggregate under all life stages and mating conditions. Bed bugs may choose to aggregate because of predation, resistance to desiccation, and more opportunities to find a mate. Airborne pheromones are responsible for aggregations.[20]
Bedbugs are most often found in hotels, hostels, shelters, and apartment complexes where lots of people come and go. Because bedbugs hide in small crevices, they can hitch a ride into your home on luggage, pets, furniture, clothing, boxes, and other objects. Bedbugs are found worldwide, but are most common in developing countries. Once rare in North America, they may be on the rise due, in part, to increases in international travel.
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