In addition to the physical manifestations of bedbug bites, patients can experience significant psychological distress. The stigma that bedbugs are related to poor hygiene (however inaccurate) can lead to poor self-esteem, avoidance of family and friends, and suspension from work.37–39 Management of an infestation can be stressful, costly, and disruptive to everyday life. Worry can lead to insomnia, depression, anxiety, and even delusional parasitosis.37
Just recently had my first experience w/ bedbug bites in Nicaragua. Hundred plus bites in one night and over a period of three days they became so inflamed, there were tiny blisters on each bite. These suckers snacked on me like I was an all you can eat buffet. I itched 4 days straight and finally went to a pharmacy there, which prescribed me acne creme. Worked, I guess, at least psychologically. But the bites kept festering more and more.
Bed bug eradication is challenging and it’s prudent to hire a professional when resources allow. However treatment can be expensive, often costing hundreds or thousands of dollars. Those who cannot afford this often must cope with the problem themselves. A useful step that anyone can take to combat bed bugs is to install bed encasements. Covering the mattress and box spring can help eliminate a substantial portion of the bed bug population -- especially if discovered early while most of the bugs are still confined to the bed area. Extra care should be taken when installing budget encasements since these can tear easily, especially on metal bed frames. Ideally both the mattress and box spring should be encased. If only one encasement is possible it’s often best to cover the box spring which is harder to subsequently inspect.
Traditional methods of repelling and/or killing bed bugs include the use of plants, fungi, and insects (or their extracts), such as black pepper; black cohosh (Actaea racemosa); Pseudarthria hookeri; Laggera alata (Chinese yángmáo cǎo | 羊毛草); Eucalyptus saligna oil; henna (Lawsonia inermis or camphire); "infused oil of Melolontha vulgaris" (presumably cockchafer); fly agaric (Amanita muscaria); tobacco; "heated oil of Terebinthina" (i.e. true turpentine); wild mint (Mentha arvensis); narrow-leaved pepperwort (Lepidium ruderale); Myrica spp. (e.g. bayberry); Robert geranium (Geranium robertianum); bugbane (Cimicifuga spp.); "herb and seeds of Cannabis"; "opulus" berries (possibly maple or European cranberrybush); masked hunter bugs (Reduvius personatus), "and many others".
Individual responses to bites vary, ranging from no visible effect (in about 20–70%), to small macular spots, to prominent wheals and bullae formations along with intense itching that may last several days. The bites often occur in a line. A central spot of bleeding may also occur due to the release of anticoagulants in the bug's saliva.
Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.