To treat an allergic reaction, the doctor may prescribe an antihistamine, corticosteroid, or epinephrine injection. If the area is infected, he or she might prescribe an antibiotic or recommend an over-the-counter antiseptic. Finally, if it’s severe itchiness that you’re dealing with, applying corticosteroid or taking an antihistamine in pill or liquid form may be able to help.
Dusts last longer than aerosols, but the crack and crevice tips on the Phantom and Bedlam areosols enable you to get into the smallest cracks. It is a good idea to use a combination of sprays and dusts. Temprid SC may be used on the tufts and seams of mattresses. It works well as a residual insecticide sprayed in other recommended treatment areas such as night stands, chests, dressers, couches and chairs.
Thanks so much to the person who mentioned the hot/cold water method! I think when you do it when you first notice the bites, It will keep them from becoming huge, itchy welts! I run hot water over the bites and I feel a sense of relief, as if I’m scratching the bite, without actually scratching it. The area turns pink, and I keep going until the relief sensation has subsided, then I run cold water over the area. Works great and it does last for hours!
I have had one bite in threes which cleared up in days and an occasional acne looking sore on my but and arm. I have noted in my car lots of little bites but no marks. My son does not appear to have bites. once he had one on his back that cleared quickly. I really needs some help here as I am getting obsessive with cleaning and making my child change and bath. I have checked my cat for flees and bought her a flee collar as I am thinking the stinging bites I get in the day may be from flees but no itch or real marks. Help please.
Wash the bites with soap and water. Wash the area with mild soap and water; use a bar of soap and enough water to wet surface of your hands. Work the soap in your hands into thick, soapy lather. Rub the lather over the affected area liberally. Repeat until the entire area is covered. Leave on and do not rinse. Allow the soap lather to dry over the bitten areas. You should experience immediate relief from itching.[5]
Bedbugs are small wingless insects with a flat body. Like all insects, they have six legs. Their color can range from whitish to brown, but after feeding (on blood from animals or people), they appear rusty red. Bedbugs grow to about 0.5 cm in length and can be seen by the naked eye. Their name comes from the fact that they often hide in bedding or mattresses.
This pair of bed bug bite photos below show the immediate (left) and next day (right) reaction after feeding a colony of bedbugs from a container in the lab. (That's why they are contained in a small circular area).  The hive-like immediate symptoms are replace by dark red rash type reaction the following day with inflammation and less severe redness radiating out to a larger area.  

Insecticides might also have their work cut out for them: Entomologists have known that the common bedbug has built up resistance to some typical insecticides such as those containing certain pyrethroid chemicals like deltamethrin, according to Entomology Today. Deltamethrin apparently paralyzes an insect's nervous system, according to Cornell University.
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Mechanical approaches, such as vacuuming up the insects and heat-treating or wrapping mattresses, are effective.[3][6] An hour at a temperature of 45 °C (113 °F) or over, or two hours at less than −17 °C (1 °F) kills them.[6] This may include a domestic clothes drier for fabric or a commercial steamer. Bed bugs and their eggs will die on contact when exposed to surface temperatures above 180 degrees and a steamer can reach well above 230 degrees.[31][15] A study found 100% mortality rates for bed bugs exposed to temperatures greater than 50 °C (122 °F) for more than 2 minutes. The study recommended maintaining temperatures of above 48 °C for more than 20 min to effectively kill all life stages of bed bugs, and because in practice treatment times of 6 to 8 hours are used to account for cracks and indoor clutter.[32] This method is expensive and has caused fires.[6][15] Starving them is not effective as they can survive without eating for 100 to 300 days, depending on temperature.[6] One expert recommends not trying to get rid of bed bugs exclusively on one's own.[29]
If I go to an infested apartment, then when I leave I check my shoes very carefully for bugs that may have crawled onto them. I also keep a change of clothes in my garage and put them on before entering my house. Once inside, I immediately put the clothes I wore to the infested apartment in the dryer, which is located in a room just off the garage.

One thing I’ve noticed is my cat is unaffected by all this. I’m assuming I’m the tastier option of the two but I’m not discounting the fact she may be spreading eggs around my apartment. she has been carefully inspected from tip to tail with a nit brush and she has no bites, isn’t scratching and seems to be just as snug as a bug in a rug. To be precautionary I am going to begin dusting her with flea powder in the morning when i go buy some.
Claude suggested a “hot as you can stand it” shower or bath to treat the bites. The itching will intensify for a few seconds, but then there is the relief which lasts for many hours. Some believe that the heat from the water overloads the ends of your nerves and prevent them from telling your brain to itch. Some think that the heat causes your body to release more histamine than usual and thereby less histamine around the bite. Whatever the reason, it’s commonly used as a solution to itching caused by bites.
Never treat any bedding, mattress, etc. with anything other than the treatments listed: borax, enzyme cleaner, Comet, sodium borate. Other pesticides and exterminating fluids can be harmful to humans. Even so, bedding and mattresses treated with chemicals such as borax or Comet should be left outside to dry naturally in the sun, then wrapped in plastic before next use, so as not to irritate the skin.
Bed bugs are a growing problem in schools and daycares. Typically they are introduced by students or staff living with an infestation at home. Pinpointing where the bugs exist can be challenging in such environments since there are no beds or sleeping areas for the insects to congregate. (Similar challenges occur when bed bugs are found in offices, libraries and retail stores.) Usually only small numbers of bed bugs are spotted, often on a student’s clothing, backpack, chair or desk. While this does not necessarily confirm that the child’s residence also has bed bugs, the parents should be notified that the home should be inspected, preferably by a professional. Teachers, nurses, and staff should be educated about the bugs and what they look like. Bed bugs should also be considered if a student frequently has reddened itchy welts --but keep in mind such reactions can be for reasons other than bed bugs. 

Wash all things washable and leave in HOT dryer for at least 20 minutes. The old timers used to sun dry and air their hand made quilts outside in the sun all day and bring them in before the dew would start to settle. they also did their mattresses and pillows and cushions and this must have heated up things a bit but be careful that the sun doesn’t fade the color.
Excessively scratching the itchy, bitten areas also may increase the chance of a secondary skin infection. Antiseptic creams or lotions can be used to ward off infection and antihistamines can be used to treat the itching. And an infestation can take a psychological toll on those affected: People whose homes have been infested with bedbugs may have trouble sleeping for fear of being bitten in the night. There are also public health, social and economic consequences; office buildings and schools often have to close if they are dealing with a bedbug infestation.
On Tuesday my arm became worse after spending the night at my friend’s place. At home, when I got out of the shower a bug near my jeans and killed it. I called my doctor to treat my arm and mentioned the bug. He saw me that day and put me on prednisone. Last night I took the antihistamine he prescribed, and it knocked me right out. I fell asleep on my friend’s shaggy carpet for about an hour and a half. As I awoke, I saw another bug run across my shorts.
After being treated by a dermatologist for nearly 2 mos for red marks all over my body – he stated that I did not have bed bug bites (he even took a biopsy of my skin) and said I had leichen planus. I took pills for 2 weeks and then began ultra violent light treatments – nothing was helping them go away. Finally, I called an exterminator to inspect my home only to find out we have bed bugs and the marks on my body are bed bug bites. I stopped going to the dermatologist and wasted 2 months precious time in getting rid of the bugs. They are driving me crazy – had my first extermination done (2 more needed) and still seeing the bugs and getting bit – can’t sleep a wink – any suggestions to help with the anxiety I’m going through would be greatly appreciated.

Its important to note that bed bugs can easily be transferred from other locations (such as hotels, friends, etc.) into your bedroom, something your definitely want to avoid! Its important to always check your skin, clothing and bags for any signs of bed bugs (and their bites) before entering your bedroom after sleeping away from the home. If you have been bitten a couple times, there is usually no urgent need for medical care. In fact, there are a number of effective home remedies that you can use to treat these insect bites. However, sometimes medical assistance is required. When is this the case and how can you identify when professional help is needed?
In most cases, the only way to say for sure whether it was a bedbug that bit you is to search for evidence of bedbugs living in your home. "Once you start to notice the itchy bites, the second giveaway is the presence of small blood spots on your sheets or mattress, usually resembling patches of rust,” Durham says. Those spots are left behind after a bedbug has been smashed.
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