Data Sources: A PubMed search was completed in Clinical Queries using the key terms bedbug, rash, bites, and infestation. The search included meta-analyses, randomized controlled trials, clinical trials, case reports, and reviews. We also searched the online databases of the Environmental Protection Agency, Centers for Disease Control and Prevention, and Jefferson Clinical Images. Lastly, we used Essential Evidence Plus. Search dates: February through June 2011.
But the bites will look different from person to person, and some people won’t develop any reaction whatsoever. “The same bedbug could bite two different people and one could have no reaction at all and the other can have an extreme reaction with a swollen arm or itchy rash,” says Eric Braun, a board-certified entomologist and business manager for the national pest control company Rentokil Steritech, who is based in Redding, Pennsylvania. Some people end up developing a rash that looks like eczema. (5)
The symptoms of a bedbug bite are usually mild when present, and often individuals will not experience any symptoms at all. Bedbug bites can occur on any exposed part of the body, with the face, neck, arms, and hands being areas commonly affected. The signs and symptoms can appear from minutes to days after the initial bite. Affected individuals will usually complain of localized itching and reddish-colored skin lesions, which may look like a flat welt or a raised bump. Sometimes, the lesions can be found in clusters or in a linear pattern. Typically, these skin lesions will go away after one to two weeks.
i just recently stayed at the A-1 Motel and our bed had bed bugs. i really want to get rid of these bites because they itch so bad. i have them all over both my arms, legs, neck, back, and my stomach. i want to get rid of them so i can go out in public without having to be embarrassed over them. i will try the baking soda and water thing and i hope it will work.

The treatment of bedbug bites depends on the symptoms and their severity. The bites should heal and disappear in one to two weeks whether you treat them or not. The goal is to prevent scratching the itchy rash, which can lead to a skin infection. You can use over-the-counter (OTC) anti-itch creams such as calamine lotion or those containing diphenhydramine or cortisone. Be sure to read the product label and don't use these creams around the eyes, anus, or genitals.


Bed bugs were mentioned in ancient Greece as early as 400 BC, and were later mentioned by Aristotle. Pliny's Natural History, first published circa AD 77 in Rome, claimed bed bugs had medicinal value in treating ailments such as snake bites and ear infections. (Belief in the medicinal use of bed bugs persisted until at least the 18th century, when Guettard recommended their use in the treatment of hysteria.[51])
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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