Jump up ^ John Southall. "That soon after the Fire of London, in some of the new-built Houses they were observ'd to appear, and were never noted to have been seen in the old, tho' they were then so few, as to be little taken notice of; yet as they were only seen in Firr-Timber, 'twas conjectured they were then first brought to England in them; of which most of the new Houses were partly built, instead of the good Oak destroy'd in the old". A Treatise of Buggs [sic], pp. 16–17. Retrieved 1 December 2016.
Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
Firstly, its important to remember that, despite their daily diet of blood, bed bugs will not transfer blood based diseases (such as AIDS, etc.). However, in very rare cases, these bites have been known to cause Anaphylaxis, which is an adverse allergic reaction that covers the entire body in a rash. After being bitten by a bed bug, be alert for any of these potential complications:
However, always remember that these simply treat the problem and do not get down to the root cause. You will still need to take steps to get rid of them! Here are a couple home remedies to get rid of bed bugs that have been extremely helpful to the community. I encourage you to take a look at that article if you are serious about removing them properly.

However, another thing which has helped me with the intense itching is a regular hair brush! I was scratching so much that I grabbed the hair brush and used that to cover more territory! I have found that even if I “brush” intensely, it will not bleed and slowly the itching will subside. I have also heard of a quirky aid in “bug direction”…..used dryer sheets will discourage bugs from the area….what I saw was the sheets tucked in between the mattress and box spring by each bedpost.
I have read about this remedy online but i haven’t tried it yet but i think it will work pretty well . After u have been bitten and u find the bites in the morning on ur body , if ur itching , its going to make it worse so try not to scratch but if u cant help yourself , i have this remedy ! Ok , so put vinegar onto ur fingers and dab it at the spots..its a great itch-relief (if thats a word) !
Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 
Bedbugs are small, flat, wingless insects with six legs that, like mosquitoes, feed on blood from animals or people. They range in color from almost white to brown, but they turn rusty red after feeding. The common bedbug doesn't grow much longer than 0.2 inches (0.5 centimeters) and can be seen by the naked eye to the astute observer.  Bedbugs get their name because they like to hide in bedding and mattresses.
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