Bed bugs can result in a number of health effects including skin rashes, psychological effects and allergic symptoms.[5] Bed bug bites may lead to skin changes ranging from non visible to prominent blisters.[1] Symptoms may take between minutes to days to appear.[2] Itchiness is common, while some may feel tired or have a fever.[2] Typically uncovered areas of the body are affected.[2] Classically three bites occur in a row.[2] Bed bugs bites are not known to transmit any infectious disease.[5][7]
Preparing for bed bug treatment is tedious yet important. Very comprehensive preparation is necessary when infestations are heavy and the bugs are widely dispersed. More limited prep may be adequate for light infestations since at these levels the bed bugs typically are more confined to sleeping areas (beds, sofas, and recliners). Pest control firms have their own policies, however, regarding preparation requirements which may also depend on the manner of treatment. 
Many chemical pesticides are available, with more than 300 registered by the EPA. Pesticides should be applied to walls, floors, cracks in furniture, and seams and buttons of mattresses.21 The EPA’s Bed Bug Products search tool (Web site: http://cfpub.epa.gov/oppref/bedbug/) allows users to search by product name, company, EPA registration number, location of intended use, and pesticide type. The National Pesticide Information Center (Web site: http://npic.orst.edu/; telephone: 800-858-7378) is another useful resource. Silica gel dusts are a safer alternative to traditional pesticides, because they are less concentrated and less toxic.21 Plastic mattress and pillow encasements can help trap bedbugs and restrict spread.42 Regardless of the integrated pest management strategy used, a follow-up inspection 10 to 21 days after extermination is advised to detect and manage a persistent infestation.42
Bites on dogs and cats will look much like bites on people, and the pet owner may actually suspect a mosquito or flea bit the pet. As with people, bed bugs do not stay on pets, but return to a protected harborage site after feeding. In addition to bites, the presence of the bug’s feces, cast skins and the animal’s irritation at night are also indicators of bed bugs biting pets. Therefore, one of the best things to do is inspect the pet’s bedding and frequently groom the animal while being vigilant for the telltale signs of bed bug presence.
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