Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).
Flea bites are caused by the parasitic insect, the flea. The most common species of flea in the US is the cat flea, Ctenocephalides felis. Signs and symptoms of flea bites in humans include itching, hives, a rash with bumps, red spots with a "halo," and swelling around the bite. Treatment for flea bites includes over-the-counter medicine and natural and home remedies to relieve and soothe itching and inflammation. The redness of a flea bite can last from a few hours to a several days.
Excessively scratching the itchy, bitten areas also may increase the chance of a secondary skin infection. Antiseptic creams or lotions can be used to ward off infection and antihistamines can be used to treat the itching. And an infestation can take a psychological toll on those affected: People whose homes have been infested with bedbugs may have trouble sleeping for fear of being bitten in the night. There are also public health, social and economic consequences; office buildings and schools often have to close if they are dealing with a bedbug infestation.
About five weeks ago bed bugs were found out work, then two weeks ago they spread, pest control has seen continuously coming to check and yesterday they gave the place the green light. I work with a largely indigent populace, the office I work at was not sprayed, during the night at some point, I will feel painful stings, hours later I have been finding small lumps or even large and hard ones, Could it be bed bugs? There is a particularly painful lump on the back of my thigh, it’s very hard too.
Great stuff to use. My former girlfriend gave me a parting gift of bedbugs she got while staying at her parents house. She was good enough to leave me some cortisone though which I needed for the first time this morning. I had being seeing bedbugs and routinely treating them for about 2 months and I had laid diatomaceaous earth around my bed and didn’t have any itching or real issues. The layer had been wearing thin and I was too lazy to respreads. Last night I slept in the nude and woke up with the worst itching and now a rash all over my body. I had been seeing bedbugs and killing them for a month or two on and off and thought what’s the big deal. Now if know!!! This is the worst case of itching I’ve ever experienced!! Luckily I have the cortisone but it’s not helping too much. I’m blasting off a bed bug bomb my brother gave me 2 months ago that I never used and respreading the diamo earth. I checked my mattress and found literally only 2 bugs a very small nymph and an adult but they must be somewhere else because my body is covered in a rash. Maybe I finally reacted to bites I had been getting in the past or more are hiding elsewhere but I’m going to rid myself of these pests. Wish I could rid the world of them!!! This itching is the worst!!
In the case of beds, a more economical option is to encase both the mattress and box spring in a protective cover like those used for allergy relief. Encasements specifically designed to help protect against bed bugs are available through retail or pest control firms. Higher quality ones tend to be more durable and comfortable to sleep on. Once the encasement is installed and zipped shut, any bugs which happen to be inside are entombed and eventually will die. Encasements also help protect newly purchased beds, and make it easier to spot and destroy any bugs residing on the outer surface during subsequent examination. Encasements will not, however, keep bed bugs from crawling onto a bed and biting a sleeping person.
A number of other symptoms may occur from either the bite of the bed bugs or from their exposure. Anaphylaxis from the injection of serum and other nonspecific proteins has been rarely documented.[5][10] Due to each bite taking a tiny amount of blood, chronic or severe infestation may lead to anemia.[5] Bacterial skin infection may occur due to skin break down from scratching.[5][11] Systemic poisoning may occur if the bites are numerous.[12] Exposure to bed bugs may trigger an asthma attack via the effects of airborne allergens although evidence of this association is limited.[5] There is no evidence that bed bugs transmit infectious diseases[5][7] even though they appear physically capable of carrying pathogens and this possibility has been investigated.[5][3] The bite itself may be painful thus resulting in poor sleep and worse work performance.[5]

Bed bug infestations are primarily the result of two species of insects from genus Cimex: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] These insects feed exclusively on blood and may survive a year without eating.[3] Adult Cimex are light brown to reddish-brown, flat, oval, and have no hind wings. The front wings are vestigial and reduced to pad-like structures. Adults grow to 4–5 mm (0.16–0.20 in) long and 1.5–3 mm (0.059–0.118 in) wide.
We had bed bugs two years ago and I was hyper allergic. I’ve been paranoid every since. This morning I woke up with five marks on my stomach and am now terrified. When I got bit before it was my hands arms or face but it was my stomach… I wear guys shirts so my stomach was definitely fully covered. There have been zero signs for two years and suddenly five marks on my stomach. Is this some sort of rash or did they suddenly come out of nowhere within a night?
No two people react to bites in the same way, although some reactions are similar. Because of the saliva that they leave behind, the first reaction is usually severe itching and irritation. This is often followed by a raised appearance on the contacted area. Some people, however, react by having welts and hives all over the body. Still others will have small, pinkish bumps that are concentrated in one area.

Bedbugs lurk in cracks and crevices and they've been living on human blood for centuries. Though they aren't known to transmit disease or pose any serious medical risk, the stubborn parasites can leave itchy and unsightly bites. However, bedbugs don't always leave marks. The best way to tell if you have a bedbug infestation is to see the live, apple-seed-size critters for yourself. Unfortunately, once bedbugs take up residence in homes and businesses, they can be difficult to exterminate without professional help.
I am constantly being bitten and it wakes me up from the itch, I bought calamine lotions and anti-itch products the calamine works the best for the itch. I don’t scratch them because they can get really infected…but it keeps me up for hours through out the night which keeps me tired all the time and I have to go to work in the morning with lack of sleep. I had to go to the board of health in my town to get the landlord to have my apartment treated…it’s a long process and it could be expensive with all the lotions I have to buy for the itch.

Went on vacation with my husband, just 3 weeks ago. Stayed at a motel in Daytona. Had a double bed. Slept with my husband the first night, we did not go under the cover. The next night slept in the other bed, went under the cover and low and behold felt something biting me in the middle of the night, so I went on top of the cover for the rest of the night. Told my husband about it when we awoke.


Bed bugs are a traveler's nightmare. They can be picked up in hotel rooms, leaving red itchy bumps and possibly rashes to ruin your vacation. Or even worse: If you accidentally bring them back with you, they could infect your whole house. To prevent a plague of bed bugs, here are some tips of what to check while you're on the road and how to determine the symptoms of bed bug bites.
While cleaning up infested areas will be helpful in controlling bedbugs, getting rid of them usually requires chemical treatments. Because treating your bed and bedroom with insecticides can be harmful, it is important to use products that can be used safely in bedrooms. Do not treat mattresses and bedding unless the label specifically says you can use them on bedding.
×