I have what I guess can be described as a mild case of bed bugs in one of my cars, weird I know but in the process of taking care of it. Anyway I get bites around my elbows and it gets really itchy and bothersome for almost a week. What I found works wonders for me is simply taking 1000 mg of motrin once a day. I had a huge welt that looked swollen and red and taking motrin calmed it down and made it stop itching for almost a full day at a time.
I use witch hazel with aloe vera (from Thayers). Apply with Q-tip or cotton ball. WORKS VERY WELL for me, especially when applied soon after bite is detected. Found that if it stings a bit when applied, it is likely that bite was recent, and more likely to reduce the itch. If I apply soon after a bite, I feel a little sting from the astringent, and the itch if often eliminated (although not sure how large the bugs are that bit me).

First, there should be a thorough inspection of areas that may be infested to identify bedbugs. Once a room is identified as infested, don't remove anything from the room unless it is sealed in a plastic bag. Furniture and items that you want to discard rather than treat should be bagged and destroyed so other people don't use them. Call your trash collection agency to arrange for an immediate pickup. Reduce the clutter in the room and discard any cardboard boxes as they can harbor bedbugs. Vacuum the area and seal the vacuum bag in a plastic bag and discard it.
It is also recommended to put infested items, such as a mattress, in a sauna that reaches temperatures of upwards of 170° Fahrenheit. Similarly, they also perish in extremely cold temperatures so mattresses and other items can be cleansed of these bugs with the use of plastic wrap and dry ice. Cover the items with large plastic tarps and carefully insert dry ice, and then secure. The extreme temperature will naturally fumigate the pests.
Bed bugs are a traveler's nightmare. They can be picked up in hotel rooms, leaving red itchy bumps and possibly rashes to ruin your vacation. Or even worse: If you accidentally bring them back with you, they could infect your whole house. To prevent a plague of bed bugs, here are some tips of what to check while you're on the road and how to determine the symptoms of bed bug bites.
You can develop a skin infection if you scratch the bites. Rarely, a more severe allergic reaction to the bites could produce larger welts, blisters, or anaphylaxis. Bedbugs may also trigger asthma attacks and getting too many repeated bites could lead to anemia. Anxiety, insomnia, and sleep disturbances are common due to the stress of discovering bedbugs.

One bed bug will usually take more than one bite. Once a bed bug inserts its mouthparts and finds a suitable blood vessel, it will begin feeding. However, finding the right blood vessel may take more than one injection into the skin. In addition, bed bugs are very sensitive to movement by the host they are feeding on. Therefore, if a sleeping person moves, a feeding bed bug will probably withdraw its mouthparts and begin its search for a blood meal on another part of the body. It’s important to remember that the number of bites a person receives is not indicative of the number of bed bugs that feed on that person.
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