Bed bug bites occur most frequently while you’re asleep. As bed bugs bite they inject their victims with an anesthetic (as well as an anticoagulant), numbing the area and making it very rare for someone to wake up when bitten. Bites normally take a day or two to appear, although depending on your individual reaction they may be more visible sooner.
Items that cannot be placed in a washer or dryer can sometimes be de-infested by wrapping them in plastic and placing them outdoors in a hot, sunny location for at least a day (for example, on pavement or in a closed vehicle parked in the sun). Packing items loosely in garbage bags and elevating objects off the ground helps the heat permeate further, and will make it harder for bugs to find a cool place to hide. Monitoring with a thermometer is prudent to ensure that a temperature of at least 120°F is achieved wherever the bugs may be. 
The biggest problem with these bites is that, depending on the persons skin and their tolerance to bacteria, their appearance is different on different types of people. I have noticed in the past that if I get bitten by a mosquito, I get a rather large red mark (even without scratching), whereas my husbands skin hardly shows any signs of the bite.
For about 3 almost 4 weeks now something has been bitting me around my ankles and feet. My fiancé hasnt been bit by anything and if he has he can’t tell. I took all sheets off the bed, found nothing. i have no idea if its bed bugs or fleas. But the itching is driving me insane. My fianc roommate did bring a stray kitten into the house not to long ago, and I’m thinking its fleas. But I don’t know for a 100%. I have a couple bites on my arms but mainly on ankles and feet.there is no carpet in house, just hardwood and one rug in living rm. I saw 2 tiny tiny bugs last night, but I couldn’t grab them in time. Pplease help its driving me insane and grossing me out
Data Sources: A PubMed search was completed in Clinical Queries using the key terms bedbug, rash, bites, and infestation. The search included meta-analyses, randomized controlled trials, clinical trials, case reports, and reviews. We also searched the online databases of the Environmental Protection Agency, Centers for Disease Control and Prevention, and Jefferson Clinical Images. Lastly, we used Essential Evidence Plus. Search dates: February through June 2011.

I dont know if my post was received. I am using a phone its started acting weird and my comment was gone. My problem with bedbugs is so horrible I am trying again. I am 60 years old. I have never seen or even heard of someone having these creatures from hell.I am allergic to the bites. The red blotches quickly turned to deep red pus filled holes . Some arw very painful. I feel like my clothes have stickers in them. None of tje high priced insecticides for bedo bugs have did anything. I am actually losing it. I have used a lot of different chemicals because I am so terrible infected by their bite. I have not put a dent in the problem. I think I have poisoned myself. I have holed up in my bedroom embarassed of the bugs and the bjtes that cover my arms, legs back and toros. My son came by and I quickly rushed him outside. Completely puzzled he asked what’s is going on here ? I felt like the most horrible person. I just didnt want him to carry this curse home. I and in a hopess situation.
Thanks so much to the person who mentioned the hot/cold water method! I think when you do it when you first notice the bites, It will keep them from becoming huge, itchy welts! I run hot water over the bites and I feel a sense of relief, as if I’m scratching the bite, without actually scratching it. The area turns pink, and I keep going until the relief sensation has subsided, then I run cold water over the area. Works great and it does last for hours!
Another solution you hear about is vacuuming. You can vacuum up a lot of insects, but eggs are harder to get, and vacuuming won't in and of itself kill bed bugs. Indeed, vacuuming can end up spreading bed bugs to other rooms—when emptying the canister, for example. Pest control operators who use vacuums take measures to prevent bed bugs from escaping when the vacuum is emptied.
Bedbugs are most often found in hotels, hostels, shelters, and apartment complexes where lots of people come and go. Because bedbugs hide in small crevices, they can hitch a ride into your home on luggage, pets, furniture, clothing, boxes, and other objects. Bedbugs are found worldwide, but are most common in developing countries. Once rare in North America, they may be on the rise due, in part, to increases in international travel.
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