A number of other symptoms may occur from either the bite of the bed bugs or from their exposure. Anaphylaxis from the injection of serum and other nonspecific proteins has been rarely documented.[5][10] Due to each bite taking a tiny amount of blood, chronic or severe infestation may lead to anemia.[5] Bacterial skin infection may occur due to skin break down from scratching.[5][11] Systemic poisoning may occur if the bites are numerous.[12] Exposure to bed bugs may trigger an asthma attack via the effects of airborne allergens although evidence of this association is limited.[5] There is no evidence that bed bugs transmit infectious diseases[5][7] even though they appear physically capable of carrying pathogens and this possibility has been investigated.[5][3] The bite itself may be painful thus resulting in poor sleep and worse work performance.[5]
Bed bugs can exist singly, but tend to congregate once established. Although strictly parasitic, they spend only a tiny fraction of their lifecycles physically attached to hosts. Once a bed bug finishes feeding, it relocates to a place close to a known host, commonly in or near beds or couches in clusters of adults, juveniles, and eggs—which entomologists call harborage areas or simply harborages to which the insect returns after future feedings by following chemical trails. These places can vary greatly in format, including luggage, inside of vehicles, within furniture, among bedside clutter—even inside electrical sockets and nearby laptop computers. Bed bugs may also nest near animals that have nested within a dwelling, such as bats, birds,[22] or rodents. They are also capable of surviving on domestic cats and dogs, though humans are the preferred host of C. lectularius.[25]
So wear a face mask and just… bleach the crap out of your bed frame. Cover the mattress, repeatedly super heat your bedding and such, and bleach bleach bleach. MAKE SURE TO CHECK YOUR MATTRESS COVER. I did kill a few trying to hide in the zipper area. I picked out the crawlies with gloves and killed them, then repeatedly did a bleach scrub in case of any eggs. I do recommend the sticky traps a lot because if you keep your bed away from any walls or furniture, then the sticky traps will let you know if the bed bugs are coming from elsewhere.

No one tactic alone will be effective. A good pest control operator will develop a strategy to deal with the bed bugs that takes the particulars of the setting into account, and will return several times to check on progress. Dry ice sprays that freeze bed bugs have limited potential to reach hidden bugs. Steam has somewhat better penetrating ability. The downside of steam is that it leaves moisture behind. Dry ice doesn't leave any residue at all. Vacuuming has a role, but it has limitations, too. Some insecticides leave behind deposits that are slow to act but are effective in the long-term. Other insecticides kill on contact, but only reach insects that are in view. Insecticide resistance makes the choice of tactics more difficult.


To avoid getting bed bugs while traveling, make sure to inspect the mattress and sheets on the hotel beds, especially near the seams, mattress tags, and box spring. If you see any rusty stains, dark spots, or pale yellow patches, this could be a sign of bed bugs. Also, never put your suitcase on the bed itself or you could bring them home after your vacation. Most hotels provide a luggage rack, which is much wiser to use.
Data Sources: A PubMed search was completed in Clinical Queries using the key terms bedbug, rash, bites, and infestation. The search included meta-analyses, randomized controlled trials, clinical trials, case reports, and reviews. We also searched the online databases of the Environmental Protection Agency, Centers for Disease Control and Prevention, and Jefferson Clinical Images. Lastly, we used Essential Evidence Plus. Search dates: February through June 2011.
As for traps, these capture methods may not be full-proof for all bedbug species. Researchers have found that while both the common and tropical bedbug species have hairy feet, C. hemipterushas denser foot hairs, making this tropical insect an expert climber on slick surfaces. In the study, detailed on March 15, 2017, in the Journal of Economic Entomology, the researchers found that adult tropical bedbugs were much better at escaping traditional pitfall traps, which held onto most of the common bedbugs in the study.
During the day, bedbugs tend to hide away in furniture, floors, beds, and in wood or paper trash. They typically feed on human or animal blood at night, and most bites occur just before dawn. After taking their meal, which can last as little as three minutes, they drop off the host and crawl to a hiding place. Bedbugs can live for up to 10 months and can go without feeding for weeks.
Caregivers, firefighters, and other service providers are sometimes required to enter and work in bed bug-infested dwellings. In doing so, there is the potential to transport some bugs home or to the workplace. It should be noted that bed bugs do not fly, nor jump onto people/pets as fleas do. During the day, bed bugs usually remain hidden and immobile, becoming more active at night when seeking a host. Consequently, the chance of picking up bed bugs by merely walking into an infested dwelling during the day is unlikely. The risk may increase while providing care but can be lessened by taking some precautions. 
The diagnosis of a bedbug bite can sometimes be difficult, as bedbug bites may appear similar to the bites of other insects. A health care professional will ask detailed questions and perform a physical exam, focusing on the skin. Other organ systems will also be examined to assess for any signs of an allergic reaction or for signs of infection. No blood tests or imaging studies will be necessary. If someone is able to bring in a specimen of the insect that may have bitten them, this can be helpful in making the diagnosis.
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.
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