Bed bug bites occur most frequently while you’re asleep. As bed bugs bite they inject their victims with an anesthetic (as well as an anticoagulant), numbing the area and making it very rare for someone to wake up when bitten. Bites normally take a day or two to appear, although depending on your individual reaction they may be more visible sooner.


The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.
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