Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).
Known to be international travelers and expert hitchhikers, bed bugs are everywhere. As you travel, you increase your chances of being bit. However, knowing how to identify the bites and what your treatment options are will help you decide your next course of action. Learn more about where to look for bed bugs and how to avoid them with these great blogs:
I don’t get to see our kids; I can’t protect them from the little monsters; my own body is being eaten alive; the constant itching and scratching is embarrassing, as is the fact that I have bites and scars in visible places, and that my blood no longer clots properly, so if I get a paper cut, I’ll be bleeding a good half hour; we’ve sprayed, washed, dried and the bites keep coming; I’ve used prescription strength cortisode cream, Benadryl (which makes me tired and stupid at work), Zyrtec, Aveeno shower soap and even used my DOGS anti-itch shampoo. And I an still itching till they bleed, scarring, and finding new ones every day. I just…a part of me has totally lost hope that there will EVER be an escape and I’m so depressed I just want to go to sleep and not wake up
Bed bugs are active in summer and winter and are not considered "seasonal" in the same sense that mosquitoes, ticks and stinging insects are. Still, many consider bed bugs to be a greater problem in the warmer months, however it is not the bed bugs that are more active in the summer months - the humans are. In warmer weather we typically travel more, often sleeping in hotels and motels, using various modes of transportation, and thereby increasing our risk of exposure to bed bugs. The bed bugs themselves are year-round pests.
We exterminated our old house,called junk to pick up our furniture (it wasnt lower end items either 8 year old $140,000 furnishings it cost) sold the empty home and hope they had no problem.. We did get the empty house exterminated and told the junk collection we had bugs,I bet they kept our old furnishings as it was beautiful stuff …It made us crazy,those damn bugs…One night 12 bites on my neck,forehead and hands !! I still feel like bugs are crawling on me,I think we need psychiatric care…It took about 1 year to get over the feeling of bugs crawling on us…
2. Active Guard Liners: Active Guard Mattress Liners may be placed on beds and are effective as both preventative and active bed bug treatments. They kill bed bugs and dust mites within 72 hours and will prevent bed bugs from infesting mattresses. ActiveGuard Liners act like a fitted sheet; it comes in single, full, queen, and king sizes that fit up to 17" in depth.

Bedbugs live in any articles of furniture, clothing, or bedding, so they or their eggs may be present in used furniture or clothing. They spread by crawling and may contaminate multiple rooms in a home or even multiple dwellings in apartment buildings. They may also hide in boxes, suitcases, or other items that are moved from residence to residence or from a hotel to home. Bedbugs can live on clothing from home infestations and may be spread by a person unknowingly wearing infested clothing.
Hi can you respond to me privately? I inspected my bed mattress and linens for any signs of bed beg fecal matter and any grown bed bugs or spots of feces. I have not found any traces blood-type residue or brownish type feces in the mattress. Is it normal to find an occasional bites from something other than bed bugs? Sometimes after shaving, I will have red pimples where I have shaved.

Visit your doctor. You can also see a doctor for diagnosis if you do not find signs of bedbugs in your bed and cannot identify the source of the bites or rash. However, there is a very good chance that your physician will not be able to firmly diagnose that you have been bitten by a bedbug because the symptoms look so similar to those that result from other insect bites and skin conditions. Nevertheless, you may feel comforted by going to see your doctor, who can confirm for you that bedbugs pose little physical threat to humans.
I have no idea what works…. all the benedryl, cortizone, calamine lotion, and any cream/ointment said that they help with insect bites DOES NOT work. Once you start scratching, it’s over, you are going to scratch until the cows come home. If I am able to the trick is not to scratch at all. The enzyme is only released when you scratch, unless you are highly allergic like the picture that is show above, and I thought I was allergic, guess not.
The bites do not usually require medical treatment. Secondary bacterial infection of the skin may develop in areas that become irritated due to prolonged scratching. Topical antibiotic creams or ointments may relieve symptoms of a secondary infection. Antiseptic lotions may also be beneficial. If you've had an allergic reaction to the bedbug bites, your doctor may recommend oral antihistamine medications or corticosteroids.
Is there anything, and I do mean ANYTHING, that I can use when I go to bed at night that will revoke these little critters. Does anyone know of any strong smelling cream or spray I can use on myself so that when I lie down they will not come near me. I don’t really wanna keep complaining to the staff since I just been here two days but I’m so COVERED by these bed bug bites and constantly itching that I cry.
The life cycle stages of a bed bug are egg, nymph, and adult. The reason they are called bed bugs is that they readily infest mattresses, bed frames and box springs. Eggs are laid along the edges of or around buttons on the mattresses. Eggs can also be glued to rough surfaces. Bed bug females lay about 200 eggs, usually at the rate of three or four a day. Eggs are placed in cracks, crevices and other isolated and protected shelters. Females lay eggs after a blood meal. Eggs will hatch in one or two weeks into Nymphs. Newly hatched bugs (Nymphs) begin feeding immediately. At room temperature, and with an available food supply, the nymphal period will last 14 to 30 days. They shed their skin (Instar) five times before becoming adults. Bed bugs will mate soon after becoming mature, so the time from egg hatch to egg laying is 4 to 9 weeks, under favorable conditions. The average life span of the bed bug is 6-12 months and they feed every 10 days or so during this time. Bed bugs can survive many months without a blood meal and their reproduction is high.
CrossFire Bed Bug Concentrate has two different active ingredients for dual modes of action (both a quick kill and residual activity). Mix 3 oz of CrossFire Insecticide with one gallon of water or 0.75 oz per quart (Remember to use what you mix-within 24 hours.) Adjust the spray pattern to a mist by turning the nozzle. A low fine mist is best for most spraying, but you may need to use a stream to get into some cracks and crevices. If you can't get into the cracks and crevices use one of the aerosols described below with it's crack and crevice tips to reach into these areas.
Hi please help me out Natasha! A few days ago I woke up at midnight to find 3 bites in a almost straight line and I was afraid that it was a bed bug my mom said that there was a chance of it being a misquito since I was outside all night long but I’m still getting this weird feeling that it could be bed bugs what do you think it is can you take a guess. Help!
We suggest if you are wanting to use any type of pesticide that you should hire a professional. Bed bugs often hide in places where pesticides can’t reach and pesticides can be very harmful if not used properly. If you are still wanting to treat bed bugs yourself we suggest using food or animal grade Diatomaceous Earth instead. Diatomaceous Earth is non-toxic and will dry out the bed bugs. Also here is a link to our 8-step approach to getting rid of the bed bugs. Please let us know if you have any other questions.
The exact causes of this resurgence remain unclear; it is variously ascribed to greater foreign travel, increased immigration from the developing world to the developed world, more frequent exchange of second-hand furnishings among homes, a greater focus on control of other pests, resulting in neglect of bed bug countermeasures, and increasing resistance to pesticides.[4][38] Declines in household cockroach populations that have resulted from the use of insecticides effective against this major bed bug predator have aided the bed bugs' resurgence, as have bans on DDT and other potent pesticides.[39][medical citation needed]
Bed bug infestations are primarily the result of two species of insects from genus Cimex: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] These insects feed exclusively on blood and may survive a year without eating.[3] Adult Cimex are light brown to reddish-brown, flat, oval, and have no hind wings. The front wings are vestigial and reduced to pad-like structures. Adults grow to 4–5 mm (0.16–0.20 in) long and 1.5–3 mm (0.059–0.118 in) wide.
Many news reports in recent years have focused on the discovery of bedbugs and their health effects (even in upscale five-star hotels), and a number of lawsuits have been filed by guests of fashionable hotels who awoke to find hundreds of bedbug bites covering their skin. Searching on travel-review web sites regularly reveals information and even photos confirming the presence of bedbugs in numerous hotels.
Wash the bites with soap and water. Wash the area with mild soap and water; use a bar of soap and enough water to wet surface of your hands. Work the soap in your hands into thick, soapy lather. Rub the lather over the affected area liberally. Repeat until the entire area is covered. Leave on and do not rinse. Allow the soap lather to dry over the bitten areas. You should experience immediate relief from itching.[5]

If you arrive home and discover that you have brought some unwanted guests home with you, immediately notify the hotel of your discovery. Having a possible infestation in hotels and motels can be a public relations nightmare for the owners. Politely ask them to pay for any and all costs incurred to rid your clothing and home of a possible new infestation.

Unlike cockroaches and flies that feed on filth, there is often no relationship between bed bugs and cleanliness. Since the bugs feed solely on blood, pristine dwellings can be as vulnerable to infestation as are places of squalor. That said, poverty and privation can lead to increased risk of bed bug problems, as can the inability to hire a professional exterminator.    
Hi Samantha! I highly recommend spending about 15min to investigate your bed (especially on the corners and don’t forget to look under the sheets, etc). If there are no signs of bed bugs, then I suggest that you don’t worry about it. Additionally, I have had itchy bites after a nights sleep and it turned out to be a once off occurrence, so just take action if it keeps happening. Hope that helps, sorry for the delayed response.

My 9 yr old was diagnosed with PN, her nodules are so omggggg all I can do is cry and pray for her because it’s only her itching and 5 different doctors that can’t help me tell my Autistic beautiful lil girl your still so Beautiful, she cries. I tell Doctor’s she has heart disease and Autism please tell me they say I don’t know here is cream. Soooo cried out and helpless and depressed I am and so is she, please please help…

Don’t forget that in some cases a person does not react to bed bug bites at all. It’s really not that easy to easily identify bed bug bites. Often a diagnosis of spider bite is given when the person really doesn’t know what is causing the lesion(s). Spider bites are often an over diagnosed condition. Also, a hot or warm dryer is much more useful than washing clothes in hot water. Certain studies have shown that some bed bugs will withstand the wash, but not the dryer.


If you have been bitten by bedbugs, the good news is that they aren't associated with any disease. You need only to avoid scratching the bites and getting a skin infection. Anti-itch creams may help. Treating your home or possessions to eliminate an infestation is more of a challenge, and you may need both nonchemical and chemical treatments. Learn how to treat your bites and get rid of bedbugs.

Bed bug bites can leave you with painful inflammation and since they love to hide in beds, you may be bitten a number of times before you wake up in the morning! If you have a severe allergic reaction, its recommended that you seek professional medical assistance as soon as possible. Besides medical creams and pills, things like tea tree oil, baking soda and even lemon juice can also give you relief at minimal cost. I highly recommend that you try these first as they work really well.
Hey Ruth! If there are absolutely no signs of bed bugs (upon close inspection), its unlikely that they are the cause for the bite marks. I recommend taking another look for dark brown marks (dried blood) and other signs of their presence. Regardless, if you want to kill any bug on that mattress, just get a handheld steamer and blast it. The heat will kill everything and its completely natural. Hope that helps!

Bedbug bites may go unnoticed or be mistaken for flea or mosquito bites or other types of rash or skin conditions, since the signs of bedbug bites are difficult to distinguish from other bites or skin conditions. Bedbugs also have glands whose secretions may leave musty odors, and they also may leave dark fecal spots on bed sheets and around places where they hide (in crevices or protected areas around the bed or anywhere in the room).
We have already replaced are furniture, threw out our bed that we still haven’t be able to afford to replace I have treated the house daily with sparaies and powders. We have torn up our carpet one three rooms of the house. Did all that before getting new furniture but yet we still can’t seem to rid of these bedbugs. The infestation doesn’t seem to be as bad, yet we are still getting bitten nightly by them we don’t have a lot of money we are struggling the way it…help what can I do

I can definitely understand. This is has been going on with us for almost a year. My hands and arms look like I have leprocy or something. Horrible blisters, rash, scabs, and bunches of “bumps” especially in my right hand. I wind up with painful blood blisters some times. I am living on benedryl and calamine lotion. I hate going out because of what I look like. I have taken to using cover up and foundation on my hands to make the mess less noticable. i have a long-sleeved summer weight sweater that I wear whenever I do have to go out.
If possible get your treatment from a local outlet like Home Depot, a hardware store or an agricultural/farm supply store. If you can afford it get one of those steam mops like Shark has. It comes with a unit designed for hand steam treatments of the bed and the hot steam will kill the bugs. You will also need it if you have to treat carpeting. Professionals use a combination of treatments and you will too in order to be successful. Good luck!
Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
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