Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.

Bedbugs reproduce by a gruesome strategy appropriately named "traumatic insemination," in which the male stabs the female's abdomen and injects sperm into the wound. During their life cycle, females can lay more than 200 eggs, which hatch and go through five immature "nymph" stages before reaching their adult form, molting after each phase. [Infographic: Bedbugs: The Life of a Mini-Monster]
I dont know if my post was received. I am using a phone its started acting weird and my comment was gone. My problem with bedbugs is so horrible I am trying again. I am 60 years old. I have never seen or even heard of someone having these creatures from hell.I am allergic to the bites. The red blotches quickly turned to deep red pus filled holes . Some arw very painful. I feel like my clothes have stickers in them. None of tje high priced insecticides for bedo bugs have did anything. I am actually losing it. I have used a lot of different chemicals because I am so terrible infected by their bite. I have not put a dent in the problem. I think I have poisoned myself. I have holed up in my bedroom embarassed of the bugs and the bjtes that cover my arms, legs back and toros. My son came by and I quickly rushed him outside. Completely puzzled he asked what’s is going on here ? I felt like the most horrible person. I just didnt want him to carry this curse home. I and in a hopess situation.
Bed bugs occur in all regions of the globe.[7] Rates of infestations are relatively common, following an increase since the 1990s.[3][4][6] The exact causes of this increase is unclear; with proposals including greater travel, more frequent exchange of second-hand furnishings, a greater focus on control of other pests, and increasing resistance to pesticides.[4] Bed bugs have been known human parasites for thousands of years.[2]

Diagnosing bed bug bites can be hard for medical professionals. We often hear of doctors assuming a variety of skin conditions before bed bugs – especially doctors who haven’t encountered patients with bed bug bites before. While there is no specific test to determine whether bites are from bed bugs there are tests that can show whether or not it’s an insect bite. This is useful for ruling out issues like eczema or allergic reactions, but not for determining that any specific insect bite is a bed bug. To be sure you’ll want to check for other signs of bed bug infestation, such as the bugs themselves, moltings, and the characteristic staining of their blood meal feces.
The life cycle stages of a bed bug are egg, nymph, and adult. The reason they are called bed bugs is that they readily infest mattresses, bed frames and box springs. Eggs are laid along the edges of or around buttons on the mattresses. Eggs can also be glued to rough surfaces. Bed bug females lay about 200 eggs, usually at the rate of three or four a day. Eggs are placed in cracks, crevices and other isolated and protected shelters. Females lay eggs after a blood meal. Eggs will hatch in one or two weeks into Nymphs. Newly hatched bugs (Nymphs) begin feeding immediately. At room temperature, and with an available food supply, the nymphal period will last 14 to 30 days. They shed their skin (Instar) five times before becoming adults. Bed bugs will mate soon after becoming mature, so the time from egg hatch to egg laying is 4 to 9 weeks, under favorable conditions. The average life span of the bed bug is 6-12 months and they feed every 10 days or so during this time. Bed bugs can survive many months without a blood meal and their reproduction is high.
Some people develop allergic reactions to bedbug bites, which can include a fever, difficulty breathing, hives, or a swollen tongue. Others may develop an infection where the bite starts oozing pus. If you experience either of these reactions or you develop blisters where the bites occurred, it’s a good idea to make an appointment with a dermatologist.

Since bed bugs can be found throughout the world, many people have suffered from their bites. Since you are reading this, you have also most likely been a victim but don’t worry, you are not alone. Their primary diet is blood, which makes humans their meal of choice, definitely not good news for us! Based on personal experience, they can leave a rather nasty, red mark which can itch like mad. No wonder people say “Goodnight and don’t let the bed bugs bite!” What do these bites look like (and what to do if you are bitten) and what are some ways that you can get rid of them?
Traditional methods of repelling and/or killing bed bugs include the use of plants, fungi, and insects (or their extracts), such as black pepper;[54] black cohosh (Actaea racemosa); Pseudarthria hookeri; Laggera alata (Chinese yángmáo cǎo | 羊毛草);[15] Eucalyptus saligna oil;[55][56] henna (Lawsonia inermis or camphire);[57] "infused oil of Melolontha vulgaris" (presumably cockchafer); fly agaric (Amanita muscaria); tobacco; "heated oil of Terebinthina" (i.e. true turpentine); wild mint (Mentha arvensis); narrow-leaved pepperwort (Lepidium ruderale); Myrica spp. (e.g. bayberry); Robert geranium (Geranium robertianum); bugbane (Cimicifuga spp.); "herb and seeds of Cannabis"; "opulus" berries (possibly maple or European cranberrybush); masked hunter bugs (Reduvius personatus), "and many others".[58]
1. Mattress Safe Encasements: Mattress Safe Products are bed encasements to place over your mattress or boxspring so you don't have to throw them away. They are bedbug certified. If using a labeled insecticide on the mattress or boxspring first, apply on mattress or box springs then zip it up. It has a patented hook to keep the bed bugs inside the encasement so they cannot escape. Keep the encasement in place for one year (due to bed bug life cycles).

Bedbugs lurk in cracks and crevices and they've been living on human blood for centuries. Though they aren't known to transmit disease or pose any serious medical risk, the stubborn parasites can leave itchy and unsightly bites. However, bedbugs don't always leave marks. The best way to tell if you have a bedbug infestation is to see the live, apple-seed-size critters for yourself. Unfortunately, once bedbugs take up residence in homes and businesses, they can be difficult to exterminate without professional help.

Another clue to infestation is odor. Like many species of bugs, bed bugs release odors called alarm pheromones. When a group of bed bugs gets disturbed, you may get a whiff of that odor, which is similar to the odor stink bugs give off. At higher concentrations the odor is unpleasant. Some people say at low concentrations it's a pleasant smell—like coriander. In fact, older literature refers to the bed bug as the coriander bug. I've tried to smell the coriander scent in bed bug alarm pheromones and have not been able to make the connection, however.
I have no idea what works…. all the benedryl, cortizone, calamine lotion, and any cream/ointment said that they help with insect bites DOES NOT work. Once you start scratching, it’s over, you are going to scratch until the cows come home. If I am able to the trick is not to scratch at all. The enzyme is only released when you scratch, unless you are highly allergic like the picture that is show above, and I thought I was allergic, guess not.
Bed bugs will also succumb to cold temperatures below 32°F, but the freezing temperatures must be maintained for a longer period (e.g., one to two weeks). Consequently, heating tends to be a better option throughout much of the country. Efforts to rid entire dwellings of bed bugs by raising or lowering the thermostat will be unsuccessful, although pest control firms are able to achieve lethal temperatures with supplemental heaters (see the subsequent section entitled "Heat Treatments" for more details). 
Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.
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