Jump up ^ John Southall. "That soon after the Fire of London, in some of the new-built Houses they were observ'd to appear, and were never noted to have been seen in the old, tho' they were then so few, as to be little taken notice of; yet as they were only seen in Firr-Timber, 'twas conjectured they were then first brought to England in them; of which most of the new Houses were partly built, instead of the good Oak destroy'd in the old". A Treatise of Buggs [sic], pp. 16–17. Retrieved 1 December 2016.
Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.