Bedbug bites, like all insect bites, can become infected through excessive scratching, as underneath the fingernails lies a host of bacterial pathogens. If your bites become infected, they will appear red and swollen, feel tender and may drain pus. Typically there will not be a fever unless a substantial area of the skin is involved. If you experience any of these symptoms, you must seek medical attention as it points to a secondary infection. Your physician may prescribe antibiotic therapy or, if the infection is mild, an antiseptic medication that you can buy without a prescription.[12][13][14]
If you are experiencing itching, burning, and other forms of pain, there are a couple of treatment methods you could try. The most common recommendation is a topical corticosteroid cream or an anesthetic, which are applied directly to the wound and rubbed in to provide relief from the itching. A possible alternative to corticosteroids is calamine cream, though the FDA isn’t convinced of its effectiveness.
Before you run off and buy every cream the pharmacy stocks, you’ll want to confirm that the marks are actually from bed bugs. Even if they match the description – round, red marks that may bump, swell, itch, and/or burn – the marks could be allergic reactions to food or fabric, irritations from a rough material, or bites from another pest like mosquitoes or carpet beetles.
It’s been over a week since the first attack. I did not know where or when I got bit. Then a few days later in the night, I connected the dots. At 3 am I was up comparing bite pics on the internet and sure enough my fear was confirmed. I slept on the couch which is only 10 feet away in my studio with no problem. I did not see the actual bugs. I went and bought Steri-Fab spray–a gallon of it. I cleaned, vacuumed, sprayed the crap out of everything. I washed all my bedding in hot water. I threw out a throw rug. Sprayed baseboards again and around that side of the apartment.
Another clue to infestation is odor. Like many species of bugs, bed bugs release odors called alarm pheromones. When a group of bed bugs gets disturbed, you may get a whiff of that odor, which is similar to the odor stink bugs give off. At higher concentrations the odor is unpleasant. Some people say at low concentrations it's a pleasant smell—like coriander. In fact, older literature refers to the bed bug as the coriander bug. I've tried to smell the coriander scent in bed bug alarm pheromones and have not been able to make the connection, however.
Also, we do have pets and a 10 year old living with us as well. 3 cats and a dog. They have been fine with the bleach smell, though it seems to be making one of my cats a little wild. A suggestion I have, if you try what we’re trying, is put the animals up until the KABOOM has dried, because, where as our animals are seemingly okay, it could still harm them. Luckily our cats are indoor/outdoor cats, so we can put them outside while we do it.
In comparison to other insect bites, bed bug bite marks are usually in groups of three or more when they appear on the skin. This is sometimes called the “breakfast, lunch and supper bites”. As you can see in the picture below, the bites are rather close to each other. Their bites often look like little red bumps, pimples or even blisters and welts. Some people can also mistake them for flea bites. If one of these insects bite you, you usually won’t even feel it as it uses a form of anesthetic which dulls the pain. Bed bugs also are known to leave bite marks in a straight line, also in close proximity to each other. A single bed bug can bite you a number of times during the night. However, if you have a bed bug infestation, there are usually a large number of these little pests and this can result in a multitude of bite marks. Please also remember that some people may not have a negative reaction to these bites. In fact, sometimes they are mistaken for spider bites, even by medical professionals so make sure you let your doctor know if you feel it could be a bite from bedbugs. Lastly, you will be happy to learn that bed bugs do not fly so you won’t be attacked from the air.
3. Centers for Disease Control and Prevention; National Center for Environmental Health; Environmental Protection Agency. Joint Statement on Bed Bug Control in the United States from the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Environmental Protection Agency (EPA). Atlanta, Ga.: National Center for Environmental Health; 2010.

Español: tratar las picaduras de chinches, Deutsch: Bettwanzenbisse behandeln, Português: Tratar Picadas de Percevejos, Italiano: Trattare le Punture delle Cimici da Letto, Français: traiter des piqures de punaises de lit, Русский: лечить укусы клопов, 中文: 应对床虱叮咬, Nederlands: Bedwantsbeten behandelen, Čeština: Jak léčit štípance od štěnic, Bahasa Indonesia: Mengobati Gigitan Kutu Ranjang, Tiếng Việt: Trị Vết cắn Bọ rệp, 日本語: トコジラミの刺し跡を治療する, العربية: معالجة لدغات البقّ المنزلي, 한국어: 빈대에 물린 상처를 치료하는 법, ไทย: รักษารอยตัวเรือดกัด

First, there should be a thorough inspection of areas that may be infested to identify bedbugs. Once a room is identified as infested, don't remove anything from the room unless it is sealed in a plastic bag. Furniture and items that you want to discard rather than treat should be bagged and destroyed so other people don't use them. Call your trash collection agency to arrange for an immediate pickup. Reduce the clutter in the room and discard any cardboard boxes as they can harbor bedbugs. Vacuum the area and seal the vacuum bag in a plastic bag and discard it.
3. Centers for Disease Control and Prevention; National Center for Environmental Health; Environmental Protection Agency. Joint Statement on Bed Bug Control in the United States from the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Environmental Protection Agency (EPA). Atlanta, Ga.: National Center for Environmental Health; 2010.
Don't assume your bites are bedbugs. Bites can be hard to identify, even for doctors. Rule out mosquitoes, fleas, mites, and biting gnats by conducting a visual inspection. It's best to collect and identify bedbugs to confirm bites. Look for the bugs themselves or their bloodstains, especially along the seams of mattresses. Further, look for dark spots of insect waste where bedbugs might crawl into hiding places on furniture, walls, and floors.
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