Bed bugs were mentioned in ancient Greece as early as 400 BC, and were later mentioned by Aristotle. Pliny's Natural History, first published circa AD 77 in Rome, claimed bed bugs had medicinal value in treating ailments such as snake bites and ear infections. (Belief in the medicinal use of bed bugs persisted until at least the 18th century, when Guettard recommended their use in the treatment of hysteria.[51])
I personally did not know about bedbugs or how to treat bites. I and my family have suffered the trauma of dealing with this problem. I have little knowledge of bedbugs. It has been a very bad experience to my family. I have had to throw away many items that was precious to me. Giving up all the mattress in my home. Sleeping on the floor with jackets, socks, long pants, and long shirts. My son is has asthma. I have a major concern with his health. My family is my major concern.
The best way to confirm that the bites are from bed bugs is to find other evidence of a bed bug infestation. Common telltale signs can be found on or near your mattress: pull up your sheets and check the seams and folds for thin black fecal streaks or small red blood spots. You might also find bed bugs, living or dead, and their discarded shells in various hiding places, such as the joints of your bed frame.
When traveling, inspect the bedding prior to exposing yourself or your belongings. Seal your dirty clothes in plastic bags. You may even consider encasing your luggage in a plastic bag while you are in a hotel room. Launder your clothing as soon as you get home. You can treat your suitcase by vacuuming, using a clothes steamer, or handwashing it with hot water and soap. You might also consider encasing luggage in a plastic bag between trips.
Hey Ruth! If there are absolutely no signs of bed bugs (upon close inspection), its unlikely that they are the cause for the bite marks. I recommend taking another look for dark brown marks (dried blood) and other signs of their presence. Regardless, if you want to kill any bug on that mattress, just get a handheld steamer and blast it. The heat will kill everything and its completely natural. Hope that helps!
In comparison to other insect bites, bed bug bite marks are usually in groups of three or more when they appear on the skin. This is sometimes called the “breakfast, lunch and supper bites”. As you can see in the picture below, the bites are rather close to each other. Their bites often look like little red bumps, pimples or even blisters and welts. Some people can also mistake them for flea bites. If one of these insects bite you, you usually won’t even feel it as it uses a form of anesthetic which dulls the pain. Bed bugs also are known to leave bite marks in a straight line, also in close proximity to each other. A single bed bug can bite you a number of times during the night. However, if you have a bed bug infestation, there are usually a large number of these little pests and this can result in a multitude of bite marks. Please also remember that some people may not have a negative reaction to these bites. In fact, sometimes they are mistaken for spider bites, even by medical professionals so make sure you let your doctor know if you feel it could be a bite from bedbugs. Lastly, you will be happy to learn that bed bugs do not fly so you won’t be attacked from the air.
However, another thing which has helped me with the intense itching is a regular hair brush! I was scratching so much that I grabbed the hair brush and used that to cover more territory! I have found that even if I “brush” intensely, it will not bleed and slowly the itching will subside. I have also heard of a quirky aid in “bug direction”…..used dryer sheets will discourage bugs from the area….what I saw was the sheets tucked in between the mattress and box spring by each bedpost.
Cracks and crevices of bed frames should also be examined, especially if the frame is wood. (Bed bugs have an affinity for wood and fabric more so than metal or plastic.) Wooden support slats, if present, should be removed and examined since bed bugs often congregate where the ends rest on the frame. Screw holes, knots and other recesses are also common hiding places. Headboards secured to walls should be removed and inspected. In hotels, the area behind the headboard is often the first place that bed bugs become established. Bed bugs also frequently hide within items stored under beds. 
It is important to remember that they have a very flat body that allows it to hide almost anywhere. During the initial onset of the infestation, they are only visible around the tufts and seams of the mattress. As the infestation grows, these bugs spread out and inhabit larger and larger areas. Generally they prefer rough surfaces like wood or paper for their harborages.
One bed bug will usually take more than one bite. Once a bed bug inserts its mouthparts and finds a suitable blood vessel, it will begin feeding. However, finding the right blood vessel may take more than one injection into the skin. In addition, bed bugs are very sensitive to movement by the host they are feeding on. Therefore, if a sleeping person moves, a feeding bed bug will probably withdraw its mouthparts and begin its search for a blood meal on another part of the body. It’s important to remember that the number of bites a person receives is not indicative of the number of bed bugs that feed on that person.
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