Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 
I found something that works. Diatomaceous earth or perma guard. Buy a big bag. About a good 5 pounds and put it around the whole house yard in your bed in every crack the carpet. I mean all over and give it a couple days. They will be gone. I live in an apt I ha e a cat n dog. It isn’t harmful to pets or humans its 100% safe to use around kids and best of all no bed bugs no ants no roaches. I paid about $10 on ebay. Good luck and I’m telling u this worked for me.
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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