Some patients develop blisters filled with blood or bloody fluid, especially on the arms and legs. These blood blisters are extremely rare and can burst, causing bleeding or oozing of the bloody fluid. Healthcare providers are not sure if the cause of these blisters is related to the bug or the human but have found groups of patients that were all bitten by bugs on the same train exhibiting this sign.

Fumigation using a penetrating gas is another way to de-infest dwellings or furnishings, but the procedure is only offered by certain companies. True fumigation is not the same as setting off a total release fogger or ‘bug bomb.’ (It should be noted that bug bombs are considered ineffective in the treatment of bed bugs, and can be quite dangerous if misused.) The fumigation process is technically complex and requires vacating the building for a period of days. The building is then sealed and injected with a lethal gas, usually sulfuryl fluoride. Because the entire building must be vacated, structural fumigation is logistically more challenging with multi-unit buildings such as apartments, than for single family homes. Bed bug fumigations tend to be more common in southern and western states, where the procedure is also used to control certain types of wood-dwelling termites.  
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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