If you know that you have the bugs. Get sealing covers the kind that encloses completely, one for the mattress and one for the box spring. That will trap those critters inside and they will eventually die in there. Next you will need to decide of what combination of treatments you wish to use. Its a job that you will have to keep up with for some time. Do your research online first.
Many news reports in recent years have focused on the discovery of bedbugs and their health effects (even in upscale five-star hotels), and a number of lawsuits have been filed by guests of fashionable hotels who awoke to find hundreds of bedbug bites covering their skin. Searching on travel-review web sites regularly reveals information and even photos confirming the presence of bedbugs in numerous hotels.
Bed bugs were mentioned in ancient Greece as early as 400 BC, and were later mentioned by Aristotle. Pliny's Natural History, first published circa AD 77 in Rome, claimed bed bugs had medicinal value in treating ailments such as snake bites and ear infections. (Belief in the medicinal use of bed bugs persisted until at least the 18th century, when Guettard recommended their use in the treatment of hysteria.[51])
In comparison to other insect bites, bed bug bite marks are usually in groups of three or more when they appear on the skin. This is sometimes called the “breakfast, lunch and supper bites”. As you can see in the picture below, the bites are rather close to each other. Their bites often look like little red bumps, pimples or even blisters and welts. Some people can also mistake them for flea bites. If one of these insects bite you, you usually won’t even feel it as it uses a form of anesthetic which dulls the pain. Bed bugs also are known to leave bite marks in a straight line, also in close proximity to each other. A single bed bug can bite you a number of times during the night. However, if you have a bed bug infestation, there are usually a large number of these little pests and this can result in a multitude of bite marks. Please also remember that some people may not have a negative reaction to these bites. In fact, sometimes they are mistaken for spider bites, even by medical professionals so make sure you let your doctor know if you feel it could be a bite from bedbugs. Lastly, you will be happy to learn that bed bugs do not fly so you won’t be attacked from the air.
When staying in a hotel, I check the bed before I bring the suitcase into the sleeping part of the room so that if I have to ask the manager for another room, then I haven't exposed my suitcase to the bugs. When settling in, I put my suitcase up on the suitcase stand or the desktop so that any bugs are less likely to crawl into it. An extreme measure would be putting the suitcase in the tub. If it's a porcelain tub, bed bugs would have a hard time crawling up it. It's also unlikely that they would randomly crawl up a tub, because it's not near the bed. But if I don't see bed bugs in the room when I inspect it, I just put my suitcase on the stand because I know the probability is really low that a bug is going to crawl up the stand and into my suitcase. I keep my clothes in the suitcase or hang them in the closet—I don't leave them on the floor because wandering bed bugs might crawl into them.

When it comes to controlling bed bugs, "do it yourself" should not be anyone's motto. Bed bugs are notoriously difficult to eradicate - 76 percent of pest professionals say they are the most difficult pest to control.  As such, people who suspect a bed bug infestation should turn to a qualified pest professional with expertise in treating these pests. The pest professional will evaluate the extent of an infestation and recommend the best course of treatment.  In fact, the Centers for Disease Control and Prevention endorses that appropriate control of a bed bug infestation requires an experienced pest management professional and recommends that victims be advised against attempting to control measures themselves.
Once you have a suspicion or a confirmed infestation, do not spread things outside of the bedroom. Don't take linens off the bed and go to sleep somewhere else—that will just move the infestation to other rooms. Ultimately pest control operators will tell you to put everything you can through the washer and dryer, since bed bugs cannot withstand high temperatures. I don't think bed bugs would be able to survive solvent-based dry cleaning, but I don't have any first-hand knowledge that that's true. Unfortunately, dry cleaners and Laundromats can be places where people pick up bed bugs. I think it's a low probability, but it only takes one adult female bed bug that has been mated to get an infestation going.

Bed bugs occur around the world.[36] Before the 1950s about 30% of houses in the United States had bedbugs.[2] Rates of infestations in developed countries, while decreasing from the 1930s to the 1980s, have increased dramatically since the 1980s.[3][4][36] Before the 1980s they were common in the developing world but rare in the developed world.[4] The increase in the developed world may have been caused by increased international travel, resistance to insecticides, and the use of new pest-control methods that do not affect bed bugs.[37]


Some friends brought me a gift, bed bugs. After some research I discovered cedar oil. I have been using it as a repellent. I spray around my mattress at night and it seems to keep the bugs at bay. It is harmless to me and my pets and I can even use it on them to repel fleas. Has anyone else tried it? It works on the same principle as a cedar chest is used to keep bugs away from your valuable clothing or bedding items. It does have a cedar odor which I find mildly enjoyable.
Each of the following pictures of bed bug bites shows typical skin reactions to the insect's saliva. Most people  are not hypersensitive to the bites and will show no reaction at all with the exception of two small dots where the bedbug punctured the skin. Other people can develop red papular eruptions (raised inflamed areas) or in severe cases, blisters.
Caregivers, firefighters, and other service providers are sometimes required to enter and work in bed bug-infested dwellings. In doing so, there is the potential to transport some bugs home or to the workplace. It should be noted that bed bugs do not fly, nor jump onto people/pets as fleas do. During the day, bed bugs usually remain hidden and immobile, becoming more active at night when seeking a host. Consequently, the chance of picking up bed bugs by merely walking into an infested dwelling during the day is unlikely. The risk may increase while providing care but can be lessened by taking some precautions. 
Bedbug bites don’t normally require treatment by a doctor, though there are a few precautions you should take at home. (8) Start by cleaning the area with soap and water to lower your risk of infection and to relieve itchiness. If the bites are itchy, pick up a corticosteroid cream at your local drugstore and apply it to the area. The bites generally will heal within a couple of weeks. (9)

In the case of beds, a more economical option is to encase both the mattress and box spring in a protective cover like those used for allergy relief. Encasements specifically designed to help protect against bed bugs are available through retail or pest control firms. Higher quality ones tend to be more durable and comfortable to sleep on. Once the encasement is installed and zipped shut, any bugs which happen to be inside are entombed and eventually will die. Encasements also help protect newly purchased beds, and make it easier to spot and destroy any bugs residing on the outer surface during subsequent examination. Encasements will not, however, keep bed bugs from crawling onto a bed and biting a sleeping person.


The decline of bed bug populations in the 20th century is often credited to potent pesticides that had not previously been widely available.[44] Other contributing factors that are less frequently mentioned in news reports are increased public awareness and slum clearance programs that combined pesticide use with steam disinfection, relocation of slum dwellers to new housing, and in some cases also follow-up inspections for several months after relocated tenants moved into their new housing.[66]
Reports of bedbugs can be found in the popular press and on hotel and travel review sites, and they appear to be making a comeback. The good news is that they typically do not pose serious health risks, even though their bites may be uncomfortable. These slides show you how to recognize bedbugs, know where they're hiding, and learn what to do to prevent getting bitten.
Bedbug bites usually do not require any treatment. If you develop itching of the skin around the site of the bite, you can use an over-the-counter antihistamine pill or cream such as diphenhydramine (Benadryl). Some individuals may also experience relief from the itching by applying a hot washcloth directly to the affected area. Try to avoid scratching the skin, as this can cause skin breakdown and a subsequent secondary bacterial skin infection.

Chances are, you or someone you know has had a run-in with bed bugs. It might have happened in a scrupulously clean bedroom. Or maybe it was a hotel room, office or college dorm. In the February issue of Scientific American entomologist Kenneth Haynes of the University of Kentucky explains how, after a lengthy absence, bed bugs are staging a comeback. The good news is scientists are intensively studying these insects, and their insights suggest novel ways of detecting the bugs and eradicating infestations. Some of those potential solutions are a long way off, however. In the meantime the best bet is to avoid bringing bed bugs home in the first place. I called Haynes to ask him how to do that and what to do if one suspects an infestation (eek!), among a bunch of other practical-minded questions.
All these bed bugs can be dealt with. it is best to use a non chemical treatment to make it safe for your environment . here is one i found, food grade Diatomaceous Earth found at garden centers, follow instructions, and move beds away from the walls, sprinkle in the carpet deeply, on to base boards , ( it works like borax powder for fleas and roaches) .
Amazingly, these sneaky little bloodsuckers dine on you without waking you. You don't feel their stealthy bite because they inject a numbing agent into your body, along with an anticoagulant to keep your blood flowing as they suck. The first sign of bedbugs may be itchy, red bites on the skin, usually on the arms or shoulders. Bedbugs tend to leave straight rows of bites.
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