Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 
Hey Randy! Based on your description of the situation, it does sound like bed bugs. Since you have had the similar experience for 5 years, I highly recommend getting someone to take a look at your bed for bed bugs. Something that you can try in the meantime is a close inspection of your linen. If you find any tiny blood marks on the sheets, that’s a tell tale sign of the presence of bed bugs. If you like you can send me a picture and I can take a closer look

I dont know if my post was received. I am using a phone its started acting weird and my comment was gone. My problem with bedbugs is so horrible I am trying again. I am 60 years old. I have never seen or even heard of someone having these creatures from hell.I am allergic to the bites. The red blotches quickly turned to deep red pus filled holes . Some arw very painful. I feel like my clothes have stickers in them. None of tje high priced insecticides for bedo bugs have did anything. I am actually losing it. I have used a lot of different chemicals because I am so terrible infected by their bite. I have not put a dent in the problem. I think I have poisoned myself. I have holed up in my bedroom embarassed of the bugs and the bjtes that cover my arms, legs back and toros. My son came by and I quickly rushed him outside. Completely puzzled he asked what’s is going on here ? I felt like the most horrible person. I just didnt want him to carry this curse home. I and in a hopess situation.


Bedbug bites usually do not require any treatment. If you develop itching of the skin around the site of the bite, you can use an over-the-counter antihistamine pill or cream such as diphenhydramine (Benadryl). Some individuals may also experience relief from the itching by applying a hot washcloth directly to the affected area. Try to avoid scratching the skin, as this can cause skin breakdown and a subsequent secondary bacterial skin infection.
"In the past, bedbugs have repeatedly shown the ability to develop resistance to products overly relied upon for their control. The findings of the current study also show similar trends in regard to chlorfenapyr and bifenthrin resistance development in bedbugs," study researcher Ameya Gondhalekar, research assistant professor at Purdue's Center for Urban and Industrial Pest Management, said in the Entomology Today statement. "With these findings in mind and from an insecticide resistance management perspective, both bifenthrin and chlorfenapyr should be integrated with other methods used for bed bug elimination in order to preserve their efficacy in the long term."

The common bed bug (C. lectularius) is the species best adapted to human environments. It is found in temperate climates throughout the world. Other species include Cimex hemipterus, found in tropical regions, which also infests poultry and bats, and Leptocimex boueti, found in the tropics of West Africa and South America, which infests bats and humans. Cimex pilosellus and Cimex pipistrella primarily infest bats, while Haematosiphon inodora, a species of North America, primarily infests poultry.[42]
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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