It is important to remember that they have a very flat body that allows it to hide almost anywhere. During the initial onset of the infestation, they are only visible around the tufts and seams of the mattress. As the infestation grows, these bugs spread out and inhabit larger and larger areas. Generally they prefer rough surfaces like wood or paper for their harborages.


My husband for 5 yrs had been getting bites on one knee and on his stomach about every other month or so. They are maybe 3 or 4 on stomach area and maybe 6 or 7 on the knee – always same knee and same area on stomach. We wondered about bed bugs so we put DE out, corked all openings and cracks, and sprayed – we have never seen signs of the bed bugs, we put the mattress and box springs in the bed bug proof cover. If it were bed bugs would they not bite some where else and would you not get more of them after all this time? The only bug we have seen are the ones that look like lady bugs sometimes but I understand they do not bite!
General housecleaning measures, (e.g. vacuuming floors and surfaces), seldom reach where bed bugs hide. For this reason, repetitive vacuuming by occupants may not be worth the effort, especially compared to other important preparatory activities. Targeted vacuuming of bed bugs and infested harborages, however, can help remove some of the bugs before other treatment measures are undertaken. Bed bugs and especially the eggs can be difficult to dislodge. Optimum results will be achieved by moving and scraping the end of the suction wand along infested areas such as seams and fabric folds of beds and sofas, and the perimeter edge of wall-to-wall carpet. Bed bugs can survive the high speed trip down a vacuum, so it’s important to carefully dispose of the vacuum contents in a sealed trash bag afterwards. 
This pair of bed bug bite photos below show the immediate (left) and next day (right) reaction after feeding a colony of bedbugs from a container in the lab. (That's why they are contained in a small circular area).  The hive-like immediate symptoms are replace by dark red rash type reaction the following day with inflammation and less severe redness radiating out to a larger area.  
A number of other symptoms may occur from either the bite of the bed bugs or from their exposure. Anaphylaxis from the injection of serum and other nonspecific proteins has been rarely documented.[5][10] Due to each bite taking a tiny amount of blood, chronic or severe infestation may lead to anemia.[5] Bacterial skin infection may occur due to skin break down from scratching.[5][11] Systemic poisoning may occur if the bites are numerous.[12] Exposure to bed bugs may trigger an asthma attack via the effects of airborne allergens although evidence of this association is limited.[5] There is no evidence that bed bugs transmit infectious diseases[5][7] even though they appear physically capable of carrying pathogens and this possibility has been investigated.[5][3] The bite itself may be painful thus resulting in poor sleep and worse work performance.[5]
Bed bugs are not too picky when it comes to feeding. As long as skin is exposed, it’s a juicy target. However, it seems that bed bugs enjoy feeding on the neck region, making their feeding habits very close to those sparkly vampires you see on Twilight. Since most people wear pajamas when they go to sleep, other common areas for bites include the arms, hands, feet and face since they are also exposed. If you are sleeping in a hotel and are nervous about bed bugs, simply wear extra clothing to completely cover your skin. You can also purchase plastic covers to protect yourself against these pests while sleeping out.

Bedbugs do, however, have a unique bite pattern. Although some bites may appear alone, most bites occur in a row of three to five bites (termed "breakfast, lunch, and dinner") or in a cluster of red bumps (a rash called bedbug dermatitis). The bites often appear in a zig-zag formation, but may appear in a straight line if the bugs bite you in the morning.


I recently stayed at a nice resort and ended up with bed bug bites. Since I was on vacation, I had nothing with me for itching except (and don’t laugh) hemorrhoid wipes. I was desperate so I tried one and the itching would stop for a few hours (unless something touched the bites). Now after reading the posts here I see that witch hazel and aloe, both of which are in these wipes, are one of the better treatments for the itching. The wipes were great, they are “wipes to go” which means individually wrapped so I could carry one in my purse and use it throughout the day as needed and then just fold it up and put it back into the wrapper til next time. These can be bought OTC at any pharmacy and I have the store brand, not name brand.

Jump up ^ John Southall. "That soon after the Fire of London, in some of the new-built Houses they were observ'd to appear, and were never noted to have been seen in the old, tho' they were then so few, as to be little taken notice of; yet as they were only seen in Firr-Timber, 'twas conjectured they were then first brought to England in them; of which most of the new Houses were partly built, instead of the good Oak destroy'd in the old". A Treatise of Buggs [sic], pp. 16–17. Retrieved 1 December 2016.

We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you. We may share your information with third-party partners for marketing purposes. To learn more and make choices about data use, visit our Advertising Policy and Privacy Policy. By clicking “Accept and Continue” below, (1) you consent to these activities unless and until you withdraw your consent using our rights request form, and (2) you consent to allow your data to be transferred, processed, and stored in the United States.
People don't often consider bed bugs until they've left their mark. The appearance of flat, red welts in zigzag lines or small clusters is a key sign of bed bugs on humans. Bed bugs can also leave their bites in straight rows and, while they don't spread diseases to humans, their bites are quite irritating and scratching them can lead to bleeding and infection.
Amazingly, these sneaky little bloodsuckers dine on you without waking you. You don't feel their stealthy bite because they inject a numbing agent into your body, along with an anticoagulant to keep your blood flowing as they suck. The first sign of bedbugs may be itchy, red bites on the skin, usually on the arms or shoulders. Bedbugs tend to leave straight rows of bites.
×