The biggest problem with these bites is that, depending on the persons skin and their tolerance to bacteria, their appearance is different on different types of people. I have noticed in the past that if I get bitten by a mosquito, I get a rather large red mark (even without scratching), whereas my husbands skin hardly shows any signs of the bite.
The bites themselves don't usually pose any major health risk since bedbugs are not known to spread diseases, but an allergic reaction to the bites may require medical attention, CDC officials say. There have also been some strange cases linked to bedbug infestations. Researchers reported in the Canadian Medical Association Journal in 2009 that they treated a 60-year-old man for anemia caused by blood loss from bedbug bites. Another study published in 1991 in the Journal of the Egyptian Society of Parasitology found that people with asthma might be more susceptible to allergic reactions from bedbug bites.
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.