I just discovered the cause of my skin reaction this morning. Been spending a lot of time at a friends place and started to get red spots that were intense and itch. It just got worse and worse. The dermatologist did a biopsy and found no bacteria or virus. Skin scrapping found no fungus. It was a matter of finding out what was causing my skin to become so swollen I couldn’t see some of the bite marks. It only affected my legs, feet, arms, upper back, chest, neck, and shoulders. No midsection bites.
Cracks and crevices of bed frames should also be examined, especially if the frame is wood. (Bed bugs have an affinity for wood and fabric more so than metal or plastic.) Wooden support slats, if present, should be removed and examined since bed bugs often congregate where the ends rest on the frame. Screw holes, knots and other recesses are also common hiding places. Headboards secured to walls should be removed and inspected. In hotels, the area behind the headboard is often the first place that bed bugs become established. Bed bugs also frequently hide within items stored under beds. 
Symptoms may not appear until some days after the bites have occurred.[5] Reactions often become more brisk after multiple bites due to possible sensitization to the salivary proteins of the bed bug.[3] The skin reaction usually occurs in the area of the bite which is most commonly the arms, shoulders and legs as they are more frequently exposed at night.[5] Numerous bites may lead to an erythematous rash or urticaria.[5]
Treatment is symptomatic.[2] Eliminating bed bugs from the home is often difficult.[2] Part of this is because bed bugs can live for a year between feeding.[2] Repeated treatments of a home may be required.[2] These treatments may include heating the room to 50 °C (122 °F) for more than 90 minutes, frequent vacuuming, washing clothing at high temperatures, and the use of various pesticides.[2]
With practice and a flashlight, nonprofessionals can become proficient in finding and destroying bed bugs. The process is made easier by reducing clutter, especially in bedrooms and sleeping areas. Bugs that are spotted can be removed with a vacuum (see previous discussion), or killed with over-the-counter insecticides labeled for such use. Most bed bug sprays intended for householders have little remaining effect after the spray has dried. Therefore it’s important to initially contact as many of the insects as possible with the spray droplets. Insecticide labels should be read carefully as some bed bug products should not be used on mattresses and seating areas. Some insecticides applied as powders or dusts (e.g., diatomaceous earth) will kill bed bugs although boric acid powder will not. However powders can be messy and difficult to apply, especially by nonprofessionals. Total release foggers (otherwise known as ‘bug bombs’) are ineffective against bed bugs and potentially dangerous when used incorrectly (see University of Kentucky entomology fact sheet Limitations of Home Insect Foggers).
I found something that works. Diatomaceous earth or perma guard. Buy a big bag. About a good 5 pounds and put it around the whole house yard in your bed in every crack the carpet. I mean all over and give it a couple days. They will be gone. I live in an apt I ha e a cat n dog. It isn’t harmful to pets or humans its 100% safe to use around kids and best of all no bed bugs no ants no roaches. I paid about $10 on ebay. Good luck and I’m telling u this worked for me.
Turns out, C. lectularius is also forming a resistance to other insecticides, according to a study published online April 10, 2017, in the Journal of Economic Entomology. The researchers, from Purdue University, found that three out of 10 bedbug populations collected in the field showed much less susceptibility to chlorfenapyr, and five of the 10 populations showed reduced susceptibility to bifenthrin, according to a post on Entomology Today. The scientists defined "reduced susceptibility" as a population in which more than 25 percent of the begbugs survived after seven days of exposure to the particular insecticide.
Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.
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