This pair of bed bug bite photos below show the immediate (left) and next day (right) reaction after feeding a colony of bedbugs from a container in the lab. (That's why they are contained in a small circular area).  The hive-like immediate symptoms are replace by dark red rash type reaction the following day with inflammation and less severe redness radiating out to a larger area.  

I’ve cleaned the entire area…this time sprayed it all down with a bedbug killing spray (Raid). Everything, nooks, crannies, corners, the vent. I’ve also re-inspected my spare mattress. No sign of anything. I’ve gone as far as going into both. the inside of my boxspring has been saturated with the raid spray as is the “down” side of the mattress. I slashed into the side of the mattress and sprayed inside there too. I am going to be mopping with bleach in the morning and afterward I will do my spray down again.
Reactions to bed bug bites differ from person to person from none to a full-blown allergic reaction. A mild reaction may reveal flat, red bumps at the bite sites. A more severe reaction may include an irritating itch (as in my case), or swelling. Resisting the itch is incredibly difficult, but giving in to it can cause severe irritation to the skin, increasing your risk for an infection. It’s the chemicals in the bed bug’s saliva that trigger such reactions, some lasting more than two weeks.
Every morning, even after countless treatments of our bed and linens, I wake up with 20-30 new bites. I react extremely strongly to them, they can swell as big as a half dollar, and they itch sO badly I often end up ripping them open, leaving them prone to infection. I’m now a diagnoses anemic, which the doctor is sure is because of the number of bites…they are literally eating me alive…and killing me.
While cleaning up infested areas will be helpful in controlling bedbugs, getting rid of them usually requires chemical treatments. Because treating your bed and bedroom with insecticides can be harmful, it is important to use products that can be used safely in bedrooms. Do not treat mattresses and bedding unless the label specifically says you can use them on bedding.
Bedbug bites may go unnoticed or be mistaken for flea or mosquito bites or other types of rash or skin conditions, since the signs of bedbug bites are difficult to distinguish from other bites or skin conditions. Bedbugs also have glands whose secretions may leave musty odors, and they also may leave dark fecal spots on bed sheets and around places where they hide (in crevices or protected areas around the bed or anywhere in the room).
As if you needed something else to worry about, bedbugs, those pests from the old bedtime rhyme are making a comeback. More of a nuisance than a health hazard, they’re showing up to suck blood from people in hotels, college dorms, and hospitals. Take an informative look at bedbugs: what they are, where they lurk, and how to spot them before they get you.
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