Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 
A deterrence for them that we’ve found, as well as the bleach, is lavender. Blood sucking bugs don’t seem to like it too much. I don’t personally like it because the lotion that we have makes my skin itch, and I’d rather just deal with the bites since my reactions aren’t so bad to them. However, the lavender lotion has been seemingly working, at least a little bit, for my mother and sister. Although this is the case, I wouldn’t recommend it for anyone. It’s okay to use, but it doesn’t seem to be too strong at keeping them away.
The life cycle stages of a bed bug are egg, nymph, and adult. The reason they are called bed bugs is that they readily infest mattresses, bed frames and box springs. Eggs are laid along the edges of or around buttons on the mattresses. Eggs can also be glued to rough surfaces. Bed bug females lay about 200 eggs, usually at the rate of three or four a day. Eggs are placed in cracks, crevices and other isolated and protected shelters. Females lay eggs after a blood meal. Eggs will hatch in one or two weeks into Nymphs. Newly hatched bugs (Nymphs) begin feeding immediately. At room temperature, and with an available food supply, the nymphal period will last 14 to 30 days. They shed their skin (Instar) five times before becoming adults. Bed bugs will mate soon after becoming mature, so the time from egg hatch to egg laying is 4 to 9 weeks, under favorable conditions. The average life span of the bed bug is 6-12 months and they feed every 10 days or so during this time. Bed bugs can survive many months without a blood meal and their reproduction is high.

Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
Some people have no reaction whatsoever to bed bugs. In addition to not having much of an effect on the elderly, some are just not allergic. Since the irritation and welting appears as the result of an allergic reaction, it is possible to not even know that you were bitten at all. It is entirely possible for several people to live in the same house, and have one person not be affected.
Prior to the mid-20th century, bed bugs were very common. According to a report by the UK Ministry of Health, in 1933, all the houses in many areas had some degree of bed bug infestation.[65] The increase in bed bug populations in the early 20th century has been attributed to the advent of electric heating, which allowed bed bugs to thrive year-round instead of only in warm weather.[66]
Hey Randy! Based on your description of the situation, it does sound like bed bugs. Since you have had the similar experience for 5 years, I highly recommend getting someone to take a look at your bed for bed bugs. Something that you can try in the meantime is a close inspection of your linen. If you find any tiny blood marks on the sheets, that’s a tell tale sign of the presence of bed bugs. If you like you can send me a picture and I can take a closer look

I have read a lot and saw a video where professionals can heat up your house with a machine to 140deg which will kill the bed bugs.They do make bed bug sprays (raid and others) and you can get mattress covers at wallmart. the ones for allergens will do. Don’t forget to seal up zippers. Read you can mix baking soda and water to a paste put it on for an hour or so. Wichazel, st johns wort and lemon juice, aloe and peppermint oil in tub may help relieve itch. Hope this helps.
Flea bites are caused by the parasitic insect, the flea. The most common species of flea in the US is the cat flea, Ctenocephalides felis. Signs and symptoms of flea bites in humans include itching, hives, a rash with bumps, red spots with a "halo," and swelling around the bite. Treatment for flea bites includes over-the-counter medicine and natural and home remedies to relieve and soothe itching and inflammation. The redness of a flea bite can last from a few hours to a several days.
"We originally thought the bedbugs might prefer red because blood is red and that's what they feed on," study co-author Corraine McNeill, an assistant professor of biology at Union College in Lincoln, Nebraska, said in a statement. "However, after doing the study, the main reason we think they preferred red colors is because bedbugs themselves appear red, so they go to these harborages because they want to be with other bedbugs, as they are known to exist in aggregations."
Should I worry about a tick bite? Ticks are parasites that feed on blood, and although their bites are harmless they can still transmit diseases, such as Lyme disease or Rocky Mountain spotted fever. Learn what ticks are and how to recognize the signs and symptoms of a bite. This MNT Knowledge Center article also explains how to prevent tick bites. Read now

In most infestations, consultation with a professional exterminator is advised because elimination is more likely to be effective if multiple pest management methods are used. These include monitoring devices, canine detection, clutter removal, vacuuming, heat or cold treatment, sealing cracks and crevices, and judicious use of nonchemical and chemical pesticides. Monitoring devices include moat-like devices (e.g., Climbup Insect Interceptor) that trap bedbugs ascending and descending furniture legs, and emitting devices that use carbon dioxide, heat, and/or chemicals (e.g., Nightwatch monitor) that attract and trap bedbugs. Specially trained dogs are reported to detect bedbugs with 97 percent accuracy and are able to differentiate live bedbugs and viable eggs from debris remaining from previous infestations.41 Vacuuming is a highly effective method for removing bedbugs, but not eggs because these adhere to surfaces.42 High-efficiency particulate air filters eliminate bedbug allergens and debris.42  Nonchemical treatments include petroleum jelly (which can be applied to legs of furniture to prevent bedbugs from ascending), heating, and freezing (see Table 36 for effective killing temperatures).
A deterrence for them that we’ve found, as well as the bleach, is lavender. Blood sucking bugs don’t seem to like it too much. I don’t personally like it because the lotion that we have makes my skin itch, and I’d rather just deal with the bites since my reactions aren’t so bad to them. However, the lavender lotion has been seemingly working, at least a little bit, for my mother and sister. Although this is the case, I wouldn’t recommend it for anyone. It’s okay to use, but it doesn’t seem to be too strong at keeping them away.
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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