Each of the following pictures of bed bug bites shows typical skin reactions to the insect's saliva. Most people  are not hypersensitive to the bites and will show no reaction at all with the exception of two small dots where the bedbug punctured the skin. Other people can develop red papular eruptions (raised inflamed areas) or in severe cases, blisters.

In comparison to other insect bites, bed bug bite marks are usually in groups of three or more when they appear on the skin. This is sometimes called the “breakfast, lunch and supper bites”. As you can see in the picture below, the bites are rather close to each other. Their bites often look like little red bumps, pimples or even blisters and welts. Some people can also mistake them for flea bites. If one of these insects bite you, you usually won’t even feel it as it uses a form of anesthetic which dulls the pain. Bed bugs also are known to leave bite marks in a straight line, also in close proximity to each other. A single bed bug can bite you a number of times during the night. However, if you have a bed bug infestation, there are usually a large number of these little pests and this can result in a multitude of bite marks. Please also remember that some people may not have a negative reaction to these bites. In fact, sometimes they are mistaken for spider bites, even by medical professionals so make sure you let your doctor know if you feel it could be a bite from bedbugs. Lastly, you will be happy to learn that bed bugs do not fly so you won’t be attacked from the air.
It is important to remember that they have a very flat body that allows it to hide almost anywhere. During the initial onset of the infestation, they are only visible around the tufts and seams of the mattress. As the infestation grows, these bugs spread out and inhabit larger and larger areas. Generally they prefer rough surfaces like wood or paper for their harborages.
To reduce the effects of swelling and rashes, you could take an over-the-counter antihistamine, which is usually in the form of an oral pill. Be sure to check the product label for possible side effects, though: some may cause drowsiness, dizziness, irritability, and vision changes, ringing in the ears, and other disrupting symptoms. You’ll want to be careful about taking these pills if you’re going to be driving or operating heavy machinery, and you definitely want to talk to your doctor first if you’re pregnant or have high blood pressure.
Bed bugs will also succumb to cold temperatures below 32°F, but the freezing temperatures must be maintained for a longer period (e.g., one to two weeks). Consequently, heating tends to be a better option throughout much of the country. Efforts to rid entire dwellings of bed bugs by raising or lowering the thermostat will be unsuccessful, although pest control firms are able to achieve lethal temperatures with supplemental heaters (see the subsequent section entitled "Heat Treatments" for more details). 
I sleeped over my boyfreinds house just for a night my 4month old daughter and I slept on the bed and we got bit bad but my poor baby seems to have pus on her bites..she got bit even on her face her fingers etc..but funny thing my boyfreind didnt get bit, I got home and i washed everything we took in hot water dried in hot washed my beeding all her blankets the car seat was left out in the heat for 2 days..then i washed it in hot water i vacumed the whole room sprayed alcohol on the carpet on my matress..question is what more can i do? is there any chance that they could still be in my room?
I dealt with these creatures for over 7 months. thought I was going crazy. 3 doctors- allergist-GP, dermatoligist. was treated for scabies as well. every day 2-3 new bites. some days none. i did the diaclamateous earth- alcohol- website bed bug kikkers. Finally, I actually saw 3 in a box. then i called an exterminator- for bedbugs. showed him the box he came 4 times – every sat for a month. something to do with how they reproduce. luckily this was a good man and he charged 300.00 and guaranteed it. i ripped out the carpet- the baseboards- everything in my room. only saw maybe 20 bugs in total. he said i had been treating them so that was why there were so few. Finally they are gone- 2 months now. I was the only one getting bitten- my husband did not until the very end and not nearly like me. The drs do not know for sure what the bites are when we go. and when we traet ourselves we kill them… but they hatch and are not gone. Had I known i would have gladly paid the 300 in the 1st place as these things nearly made me crazy. Just my story
Once you have a suspicion or a confirmed infestation, do not spread things outside of the bedroom. Don't take linens off the bed and go to sleep somewhere else—that will just move the infestation to other rooms. Ultimately pest control operators will tell you to put everything you can through the washer and dryer, since bed bugs cannot withstand high temperatures. I don't think bed bugs would be able to survive solvent-based dry cleaning, but I don't have any first-hand knowledge that that's true. Unfortunately, dry cleaners and Laundromats can be places where people pick up bed bugs. I think it's a low probability, but it only takes one adult female bed bug that has been mated to get an infestation going.
While cleaning up infested areas will be helpful in controlling bedbugs, getting rid of them usually requires chemical treatments. Because treating your bed and bedroom with insecticides can be harmful, it is important to use products that can be used safely in bedrooms. Do not treat mattresses and bedding unless the label specifically says you can use them on bedding.
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