Preparing for bed bug treatment is tedious yet important. Very comprehensive preparation is necessary when infestations are heavy and the bugs are widely dispersed. More limited prep may be adequate for light infestations since at these levels the bed bugs typically are more confined to sleeping areas (beds, sofas, and recliners). Pest control firms have their own policies, however, regarding preparation requirements which may also depend on the manner of treatment. 
Hello all I just want to put this out there that heat is the best way to kill these little pests. I work for a company that uses heat to do structural pasteurization, in other words we heat the entire house up to 140°+ (which is higher than the the thermal kill point for bedbugs) for an hour or more (though they can only withstand that heat for less than 15 min) This has been the ONLY way to kill them with a 100% success rate since they are becoming resistant to chemicals and DDT is illegal. Some things work for some infestations but not for all, there are a lot of good ideas on here :-)

Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).

The diagnosis of a bedbug infestation should be based on the clinical history and appearance of bites. A thorough inspection of sleeping quarters by the patient, a family member, or a pest control expert may demonstrate the telltale signs of an infestation15 (i.e., specks of blood-tinged insect feces and exoskeleton casts [Figure 5]). With the aid of a magnifying glass, special attention should be given to cracks and crevices of furniture, baseboards, electrical boxes, curtains, carpet, luggage, bed frames and headboards, picture frames, wall hangings, mattress and box spring seams, peeling wall paper, clothes, and linens.37 Live bedbugs can sometimes be caught by turning on a flashlight just before dawn, when bedbugs are most active, larger in appearance, and slower to scatter because of recent feeding.40
Bed bugs are annoying insects that hide in soft, warm places like beds, couches, and clothing. These bugs feed on their hosts at night, leaving small bite marks that, though rarely dangerous, should be treated right away to prevent unwanted symptoms and potential allergic reactions. To prevent more bites in the future, you’ll need to get rid of your bed bug infestation completely.

Encasing mattresses is one of many good parts of a solution, but it doesn't get rid of the infestation. There are going to be other bugs away from the mattress, hiding nearby. What mattress covers are good at is entombing the sometimes large number of bed bugs that can live on a mattress. And because the covers tend to be uniform in color and don't have a lot of seams that the bugs can hide in, it's easier to see the insects.
I am constantly being bitten and it wakes me up from the itch, I bought calamine lotions and anti-itch products the calamine works the best for the itch. I don’t scratch them because they can get really infected…but it keeps me up for hours through out the night which keeps me tired all the time and I have to go to work in the morning with lack of sleep. I had to go to the board of health in my town to get the landlord to have my apartment treated…it’s a long process and it could be expensive with all the lotions I have to buy for the itch.
Diagnosing bed bug bites can be hard for medical professionals. We often hear of doctors assuming a variety of skin conditions before bed bugs – especially doctors who haven’t encountered patients with bed bug bites before. While there is no specific test to determine whether bites are from bed bugs there are tests that can show whether or not it’s an insect bite. This is useful for ruling out issues like eczema or allergic reactions, but not for determining that any specific insect bite is a bed bug. To be sure you’ll want to check for other signs of bed bug infestation, such as the bugs themselves, moltings, and the characteristic staining of their blood meal feces.
It’s also possible that you won’t see a reaction the first time a bedbug bites since it sometimes can take the body a while to react. (6) Some people will have an immediate reaction, while for others it could take two weeks to emerge. Your body will likely become more sensitive to bedbug bites over time, and if you get bitten repeatedly, it could be only a matter of seconds before your body shows a response.

You should look for traces of the insects in the folds of your mattresses, box springs and other places where they are likely to hide. You might be able to find their papery skins, which get cast off after molting and look like popcorn kernels but are smaller and thinner, Harlan said. They also leave small, dark-colored spots from the blood-filled droppings they deposit on mattresses and furniture. If you can touch the spot with a water-soaked towel and it runs a rusty, reddish color, you're probably looking at a fresh drop of bedbug feces, Harlan said.
Just came back from a hotel stay, have one VERY itchy bite on my wrist. I don’t know for sure that it is a bed bug bite butI haven’t unpacked my bags yet, so hopefully everything is safe. Right now I have an aloe and lidocaine gel over the bite, but when I get home I may try soaking it in tea bath. the tannin in black tea can also help with itching and swelling.
I am having a severe allergic reaction to bed bug bites and I’m 3month pregnant. So bad first they are hives that turn in blisters even on my eye lid, on the top of my hand and on my lower back, I’ve taken benedrel which only gives me about an hr of relief, then it returns and hives last for days. I’m debating going to er, how do they treat this when you’re pregnant?

Some people experience anxiety, sleeplessness and unease as symptoms of having had bed bugs. Let's face it, bed bug infestations are understandably significant psychosocial stressors, and some people may experience sleeplessness as they worry about bugs biting them or their family members. Not surprisingly, people have been known to self-isolate, avoiding family and friends out of concern for spreading the infestation, or (if word gets out that they have bed bugs) they may be avoided by friends or others in the community, or find they have problems at work.  As a result, victims of bed bug infestations may experience moderate to severe levels of stress, anxiety and depression. In severe cases, these persons should seek counseling and treatment as required.
The diagnosis of a bedbug bite can sometimes be difficult, as bedbug bites may appear similar to the bites of other insects. A health care professional will ask detailed questions and perform a physical exam, focusing on the skin. Other organ systems will also be examined to assess for any signs of an allergic reaction or for signs of infection. No blood tests or imaging studies will be necessary. If someone is able to bring in a specimen of the insect that may have bitten them, this can be helpful in making the diagnosis.
I was in europe and have always been healthy and felt fine the 2 months while there, on my drive back home I started itching my arm and didn’t think much of it. During the next few days to weeks the itching turned into welts that itched like crazy and got bigger and harder within hours. The redness would then extend out apx. the size of a 50 cent piece that would form a small scab in the middle as it would heal. Then it would heal , but the next few welts would appear in different places. They would start off as itchy flat red circles that would quickly become firm and red. I sometimes would also feel stings all over . I’ve had this problem now for over a month. One dr. told me I had mites, another said I had bed bugs. I have small scars all over my body now. I used the all over cream 4 nights ago that is supposed to kill mites. The itching is still there but not quite as bad today and yesterday. I’ m going for a third opinion tomorrow. I never knew that itching can keep me from working or actually doing anything else except for keeping calamine lotion beside me and rubbing it on me every 10 minutes. Good luck to all of you that are dealing with the same nightmare.

These things are the real vampires!!!! Just got bit over my eye, which now is all swollen and hurting, and 3 bites on my upper arm, caught the 2 little bugs on the wall next to my bed. Make sure that your bed is away from the walls. I use tea tree oil it helps to calm the itching down, I have a bad reaction to them. Not sure where the keep coming from and always in twos. Ahhhhhh!!!!!!! Can’t sleep
Encasing mattresses is one of many good parts of a solution, but it doesn't get rid of the infestation. There are going to be other bugs away from the mattress, hiding nearby. What mattress covers are good at is entombing the sometimes large number of bed bugs that can live on a mattress. And because the covers tend to be uniform in color and don't have a lot of seams that the bugs can hide in, it's easier to see the insects.
Bedbugs are most often found in hotels, hostels, shelters, and apartment complexes where lots of people come and go. Because bedbugs hide in small crevices, they can hitch a ride into your home on luggage, pets, furniture, clothing, boxes, and other objects. Bedbugs are found worldwide, but are most common in developing countries. Once rare in North America, they may be on the rise due, in part, to increases in international travel.
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