To reduce the effects of swelling and rashes, you could take an over-the-counter antihistamine, which is usually in the form of an oral pill. Be sure to check the product label for possible side effects, though: some may cause drowsiness, dizziness, irritability, and vision changes, ringing in the ears, and other disrupting symptoms. You’ll want to be careful about taking these pills if you’re going to be driving or operating heavy machinery, and you definitely want to talk to your doctor first if you’re pregnant or have high blood pressure.
Bedbugs are small, flat, wingless insects with six legs that, like mosquitoes, feed on blood from animals or people. They range in color from almost white to brown, but they turn rusty red after feeding. The common bedbug doesn't grow much longer than 0.2 inches (0.5 centimeters) and can be seen by the naked eye to the astute observer.  Bedbugs get their name because they like to hide in bedding and mattresses.

Spray all baseboards, loose plaster, behind bed frames and headboards, beneath beds and furniture, and bedsprings and bed frames. Do not apply to furniture surfaces or mattresses where people will be laying or sitting unless using a product labeled for that type of treatment. Infested bedding should not be treated, but should be removed, placed in sealed plastic bags, and taken for laundering and drying at high temperature.
The first thing is you have to be able to recognize and distinguish a bed bug from any other insect. Everything starts to look like a bed bug if you start to worry about them. An adult bed bug is about the size and shape of an apple seed. If it has not fed recently it will be flattened and brown. If it has fed it will be round in circumference and reddish. Immature bed bugs have a similar appearance to adults, with the smallest being the size of the head of a pin. You can then learn to look for their fecal spots, which can be easier to detect than the bugs themselves. Check your hotel rooms when you travel. And think twice before bringing home used furniture. If you are purchasing used furniture, ask the furniture store how they deal with bed bugs. If they have no plan whatsoever, that's probably not a good sign. If you purchase used clothing, put it through a clothes dryer on a medium to high setting for a cycle as soon as you bring it home. And before you move into an apartment, ask the landlord whether there has been a bed bug infestation, or whether the building has ever been treated for bed bugs.
I live in a high rise apt bldg. There have been reports of bed bugs since I moved in two years ago. Recently it was my turn. I see no bugs, but man o man did they have a feast on my legs, and inner thighs. I went for the ammonia trick. The only thing I had was window cleaner. It helped stopped the itch temporarily. Then I’m good for some hours. When the itch comes back, I douse again in Blue window cleaner again. Strange but true.
I have various skin lesions which might or might not be bed-bug bites–small, raised, sometimes red, sometimes itchy. The problem is I live right next door to a large park and get all kinds of insects in summer, may small enough to get through my window-screen. Also, I have Parkinson’s disease, and the meds I take for it can produce hives and itching as a side-effect. And, my bedding and mattress are all dark colored, so I likely would not see fecal stains or shed bed-bug skins.
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I use witch hazel with aloe vera (from Thayers). Apply with Q-tip or cotton ball. WORKS VERY WELL for me, especially when applied soon after bite is detected. Found that if it stings a bit when applied, it is likely that bite was recent, and more likely to reduce the itch. If I apply soon after a bite, I feel a little sting from the astringent, and the itch if often eliminated (although not sure how large the bugs are that bit me).
Spray all baseboards, loose plaster, behind bed frames and headboards, beneath beds and furniture, and bedsprings and bed frames. Do not apply to furniture surfaces or mattresses where people will be laying or sitting unless using a product labeled for that type of treatment. Infested bedding should not be treated, but should be removed, placed in sealed plastic bags, and taken for laundering and drying at high temperature.
Treatment is symptomatic.[2] Eliminating bed bugs from the home is often difficult.[2] Part of this is because bed bugs can live for a year between feeding.[2] Repeated treatments of a home may be required.[2] These treatments may include heating the room to 50 °C (122 °F) for more than 90 minutes, frequent vacuuming, washing clothing at high temperatures, and the use of various pesticides.[2]
I have what I guess can be described as a mild case of bed bugs in one of my cars, weird I know but in the process of taking care of it. Anyway I get bites around my elbows and it gets really itchy and bothersome for almost a week. What I found works wonders for me is simply taking 1000 mg of motrin once a day. I had a huge welt that looked swollen and red and taking motrin calmed it down and made it stop itching for almost a full day at a time.
I can definitely understand. This is has been going on with us for almost a year. My hands and arms look like I have leprocy or something. Horrible blisters, rash, scabs, and bunches of “bumps” especially in my right hand. I wind up with painful blood blisters some times. I am living on benedryl and calamine lotion. I hate going out because of what I look like. I have taken to using cover up and foundation on my hands to make the mess less noticable. i have a long-sleeved summer weight sweater that I wear whenever I do have to go out.
It’s also possible that you won’t see a reaction the first time a bedbug bites since it sometimes can take the body a while to react. (6) Some people will have an immediate reaction, while for others it could take two weeks to emerge. Your body will likely become more sensitive to bedbug bites over time, and if you get bitten repeatedly, it could be only a matter of seconds before your body shows a response.

Don't assume your bites are bedbugs. Bites can be hard to identify, even for doctors. Rule out mosquitoes, fleas, mites, and biting gnats by conducting a visual inspection. It's best to collect and identify bedbugs to confirm bites. Look for the bugs themselves or their bloodstains, especially along the seams of mattresses. Further, look for dark spots of insect waste where bedbugs might crawl into hiding places on furniture, walls, and floors.
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