It was stated in 2012 that no truly effective insecticides were available.[6] Insecticides that have historically been found effective include pyrethroids, dichlorvos, and malathion.[4] Resistance to pesticides has increased significantly over time, and harm to health from their use is of concern.[3] The carbamate insecticide propoxur is highly toxic to bed bugs, but it has potential toxicity to children exposed to it, and the US Environmental Protection Agency has been reluctant to approve it for indoor use.[33] Boric acid, occasionally applied as a safe indoor insecticide, is not effective against bed bugs[34] because they do not groom.[35]
Becoming a victim of a bed bug infestation is certainly devastating, but the public can rest easy knowing that these pests are not known to transmit any diseases. While it is true that some pathogens have been detected in and on bed bugs including hepatitis B, and exotic organisms such as Trypanosoma cruzi (cause of Chagas Disease, rarely found in the United States) or Wolbachia species, unlike mosquitoes and ticks, bed bugs have not been associated with disease transmission.
Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.