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As mentioned earlier, applying insect repellent at bedtime will probably not deter bed bugs from biting. When working in severely infested dwellings, there may be some benefit to spraying tops and bottoms of shoes with DEET-based repellents. Those working in bed bug-infested environments may also want to hot wash or run clothing, etc. through a dryer upon returning home or to the office.    
Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 
Bed bugs will also succumb to cold temperatures below 32°F, but the freezing temperatures must be maintained for a longer period (e.g., one to two weeks). Consequently, heating tends to be a better option throughout much of the country. Efforts to rid entire dwellings of bed bugs by raising or lowering the thermostat will be unsuccessful, although pest control firms are able to achieve lethal temperatures with supplemental heaters (see the subsequent section entitled "Heat Treatments" for more details). 
The bed bug is a universal problem yet it can be dealt with on a regular basis. used items and new items carry bed bugs. always wash and dry for 20 min. ( its the heat that kills the bug). bed pillows need to be washed and dried on a regular basis and the beds head board are full of body skin cells that attract the bugs. a good old cleaning with vaccum and wipe down is needed. keep your vac cleaned and bag empty after each use, the bugs are in the vac.
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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