Treatment is symptomatic.[2] Eliminating bed bugs from the home is often difficult.[2] Part of this is because bed bugs can live for a year between feeding.[2] Repeated treatments of a home may be required.[2] These treatments may include heating the room to 50 °C (122 °F) for more than 90 minutes, frequent vacuuming, washing clothing at high temperatures, and the use of various pesticides.[2]
As mentioned earlier, applying insect repellent at bedtime will probably not deter bed bugs from biting. When working in severely infested dwellings, there may be some benefit to spraying tops and bottoms of shoes with DEET-based repellents. Those working in bed bug-infested environments may also want to hot wash or run clothing, etc. through a dryer upon returning home or to the office.    
Here’s one for ya…I drive over the road truck. On Friday 8/13 it was miserably hot so I stayed the night in a reputable motel. I now have bed bugs in my truck!!!! I’m getting a new mattress but am going to tell them to wrap it and tape it real well until I get home and bomb my truck. Being such a small space I figure using an insect smoke bomb will work. Well, at least it better!!! I have tons of bites all over my ankles, feet, several on my face, on one arm and on both thighs. Yup, the itching sucks…
Bed bug incidents in schools are best handled by knowledgeable pest control firms. Widespread insecticide treatment of classrooms, hallways, buses, etc. is unnecessary, ineffective and imprudent. Effort instead should be spent checking chairs, desks, lockers, coat rooms, etc. in the vicinity of where the bugs were found, and treatment should be focused on those specific areas. Canine inspections can also be useful in finding small numbers of bed bugs in schools and other establishments where there are no beds.      
It is also recommended to put infested items, such as a mattress, in a sauna that reaches temperatures of upwards of 170° Fahrenheit. Similarly, they also perish in extremely cold temperatures so mattresses and other items can be cleansed of these bugs with the use of plastic wrap and dry ice. Cover the items with large plastic tarps and carefully insert dry ice, and then secure. The extreme temperature will naturally fumigate the pests.
One bed bug will usually take more than one bite. Once a bed bug inserts its mouthparts and finds a suitable blood vessel, it will begin feeding. However, finding the right blood vessel may take more than one injection into the skin. In addition, bed bugs are very sensitive to movement by the host they are feeding on. Therefore, if a sleeping person moves, a feeding bed bug will probably withdraw its mouthparts and begin its search for a blood meal on another part of the body. It’s important to remember that the number of bites a person receives is not indicative of the number of bed bugs that feed on that person.
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