Avoiding repeated bites can be difficult, since it usually requires eradicating bed bugs from a home or workplace; eradication frequently requires a combination of pesticide and non-pesticide approaches.[3] Pesticides that have historically been found to be effective include pyrethroids, dichlorvos and malathion.[4] Resistance to pesticides has increased significantly over time and there are concerns of negative health effects from their usage.[3] Mechanical approaches such as vacuuming up the insects and heat-treating or wrapping mattresses have been recommended.[3]

Bed bugs are not too picky when it comes to feeding. As long as skin is exposed, it’s a juicy target. However, it seems that bed bugs enjoy feeding on the neck region, making their feeding habits very close to those sparkly vampires you see on Twilight. Since most people wear pajamas when they go to sleep, other common areas for bites include the arms, hands, feet and face since they are also exposed. If you are sleeping in a hotel and are nervous about bed bugs, simply wear extra clothing to completely cover your skin. You can also purchase plastic covers to protect yourself against these pests while sleeping out.
Went on vacation with my husband, just 3 weeks ago. Stayed at a motel in Daytona. Had a double bed. Slept with my husband the first night, we did not go under the cover. The next night slept in the other bed, went under the cover and low and behold felt something biting me in the middle of the night, so I went on top of the cover for the rest of the night. Told my husband about it when we awoke.
I am constantly being bitten and it wakes me up from the itch, I bought calamine lotions and anti-itch products the calamine works the best for the itch. I don’t scratch them because they can get really infected…but it keeps me up for hours through out the night which keeps me tired all the time and I have to go to work in the morning with lack of sleep. I had to go to the board of health in my town to get the landlord to have my apartment treated…it’s a long process and it could be expensive with all the lotions I have to buy for the itch.
Bed bugs occur around the world.[36] Before the 1950s about 30% of houses in the United States had bedbugs.[2] Rates of infestations in developed countries, while decreasing from the 1930s to the 1980s, have increased dramatically since the 1980s.[3][4][36] Before the 1980s they were common in the developing world but rare in the developed world.[4] The increase in the developed world may have been caused by increased international travel, resistance to insecticides, and the use of new pest-control methods that do not affect bed bugs.[37]

Bed bugs were mentioned in ancient Greece as early as 400 BC, and were later mentioned by Aristotle. Pliny's Natural History, first published circa AD 77 in Rome, claimed bed bugs had medicinal value in treating ailments such as snake bites and ear infections. (Belief in the medicinal use of bed bugs persisted until at least the 18th century, when Guettard recommended their use in the treatment of hysteria.[51])
Bed bugs are very resilient. Nymphs and adults can persist months without feeding which is unusual for most insects. The ability to survive without a blood meal is longer at cooler temperatures ― potentially up to a year or longer at 55°F or less. In temperature-controlled buildings, a more typical duration is about 2 to 6 months. Consequently, it is usually impractical to leave buildings unoccupied in hopes of ‘starving out’ an infestation. When infested dwellings such as apartments are vacated, bed bugs often disperse to nearby units, or reduce their activity until the unit is reoccupied. 
1. Mattress Safe Encasements: Mattress Safe Products are bed encasements to place over your mattress or boxspring so you don't have to throw them away. They are bedbug certified. If using a labeled insecticide on the mattress or boxspring first, apply on mattress or box springs then zip it up. It has a patented hook to keep the bed bugs inside the encasement so they cannot escape. Keep the encasement in place for one year (due to bed bug life cycles).

Just an FYI – We steamed ALL of our leather reclining living rm furniture to get rid of bedbugs. In short only the single glider/recliner was saved. The large sofa and loveseat were “sacrificed” to the firepit “gods”!!! HA Ha ha!!! Really wasn’t funny AT ALL!!! Watching quite a bit of $$$ that was hard earned just goin’ up in flames. Hate them damned bugs!!! What their purpose I wonder???!!!
Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.
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