Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).

Bed bugs (Cimex lectularius) are small, flat, parasitic insects that only feed on the blood of humans and animals while they sleep. They are reddish-brown in color, about 1mm to 7mm in size, and can live for several months without a blood meal. Bed bugs are not known to spread diseases, but their presence can cause itching and loss of sleep. Excessive scratching can increase the chance of secondary skin infections. Bed bugs are found all over the world and the cleanliness does not determine the presence of bed bugs.

These blood suckers lock on to the carbon dioxide (CO2) release when sleeping. Once they have you, they head toward a warm part of your body and begin to bite. Two tubes are inserted into your body; one is used to inject a mixture of anticoagulant and anesthetic while the other is used to suck up your blood. You never notice the bites until you wake up and realize you were the main course!
I prefer not to use chemicals because I have to breathe it in. Worse if you got kid and pets. As for the itch, try salt water.. works best if you didn’t start scratching. Keep the area cool to control the inflammation and itch with a wet paper towel. Then soothe with a generous amt of aloe get. Everyone reacted differently to the bed bug bites. Good luck.

This pair of bed bug bite photos below show the immediate (left) and next day (right) reaction after feeding a colony of bedbugs from a container in the lab. (That's why they are contained in a small circular area).  The hive-like immediate symptoms are replace by dark red rash type reaction the following day with inflammation and less severe redness radiating out to a larger area.  


My bites from two weeks ago are still rough. I have used the window cleaner, cortisone and then for the open areas , antibiotic ointment. I slept in my bed last night with no problem. I will spray again and again and again in the event of new generations. They don’t sell Phantom in my area. That is supposed to kill 95% of the eggs. Wish I could find some. These little bastards are something else. Good Luck to all.
Bites on dogs and cats will look much like bites on people, and the pet owner may actually suspect a mosquito or flea bit the pet. As with people, bed bugs do not stay on pets, but return to a protected harborage site after feeding. In addition to bites, the presence of the bug’s feces, cast skins and the animal’s irritation at night are also indicators of bed bugs biting pets. Therefore, one of the best things to do is inspect the pet’s bedding and frequently groom the animal while being vigilant for the telltale signs of bed bug presence.
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