The safest and most effective approach to getting rid of bed bugs is heat treatment, in which a trained professional heats the home's rooms one by one to a temperature of 50 degrees Celsius and sustains the heat for four hours. Heat does not penetrate well into wall voids, though, so desiccant dusts are often applied to those areas. No single technique can eliminate bed bugs—combinations of approaches are essential to getting the job done.
Cracks and crevices of bed frames should also be examined, especially if the frame is wood. (Bed bugs have an affinity for wood and fabric more so than metal or plastic.) Wooden support slats, if present, should be removed and examined since bed bugs often congregate where the ends rest on the frame. Screw holes, knots and other recesses are also common hiding places. Headboards secured to walls should be removed and inspected. In hotels, the area behind the headboard is often the first place that bed bugs become established. Bed bugs also frequently hide within items stored under beds. 
To avoid getting bed bugs while traveling, make sure to inspect the mattress and sheets on the hotel beds, especially near the seams, mattress tags, and box spring. If you see any rusty stains, dark spots, or pale yellow patches, this could be a sign of bed bugs. Also, never put your suitcase on the bed itself or you could bring them home after your vacation. Most hotels provide a luggage rack, which is much wiser to use.
Some friends brought me a gift, bed bugs. After some research I discovered cedar oil. I have been using it as a repellent. I spray around my mattress at night and it seems to keep the bugs at bay. It is harmless to me and my pets and I can even use it on them to repel fleas. Has anyone else tried it? It works on the same principle as a cedar chest is used to keep bugs away from your valuable clothing or bedding items. It does have a cedar odor which I find mildly enjoyable.
Bites on dogs and cats will look much like bites on people, and the pet owner may actually suspect a mosquito or flea bit the pet. As with people, bed bugs do not stay on pets, but return to a protected harborage site after feeding. In addition to bites, the presence of the bug’s feces, cast skins and the animal’s irritation at night are also indicators of bed bugs biting pets. Therefore, one of the best things to do is inspect the pet’s bedding and frequently groom the animal while being vigilant for the telltale signs of bed bug presence.
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