Hey Walter! I always recommend natural treatments (a few are outlined in this article) but based on your description, I recommend seeking professional medical assistance. When it comes to bed bugs, if there are a few bites that are not swollen or inflamed, you can usually just treat them with a cream but if you are having an adverse allergic reaction, you may need something much stronger. Keep an eye on it and rather be safe then sorry
Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
One thing I’ve noticed is my cat is unaffected by all this. I’m assuming I’m the tastier option of the two but I’m not discounting the fact she may be spreading eggs around my apartment. she has been carefully inspected from tip to tail with a nit brush and she has no bites, isn’t scratching and seems to be just as snug as a bug in a rug. To be precautionary I am going to begin dusting her with flea powder in the morning when i go buy some.
Some pest control firms utilize specialized heating equipment to de-infest furnishings, rooms, and entire dwellings. The procedure involves heating up the infested item or area to temperatures lethal to bed bugs. Portable heaters and fans are used to gradually heat the air to about 120 - 130°F while monitoring with strategically placed sensors. By carefully controlling the temperature, bugs and eggs are killed wherever they may be without damaging household items. 
The first sign of a bed bug problem is obvious: the bed. After bed bugs feed on humans, they'll leave behind blood stains resembling small rust spots. These will usually be found near the corners and edges of the bed. Bed bugs also shed their skin, or molt, several times as they mature, so you may find their oval brown exoskeletons during your search.
Many chemical pesticides are available, with more than 300 registered by the EPA. Pesticides should be applied to walls, floors, cracks in furniture, and seams and buttons of mattresses.21 The EPA’s Bed Bug Products search tool (Web site: http://cfpub.epa.gov/oppref/bedbug/) allows users to search by product name, company, EPA registration number, location of intended use, and pesticide type. The National Pesticide Information Center (Web site: http://npic.orst.edu/; telephone: 800-858-7378) is another useful resource. Silica gel dusts are a safer alternative to traditional pesticides, because they are less concentrated and less toxic.21 Plastic mattress and pillow encasements can help trap bedbugs and restrict spread.42 Regardless of the integrated pest management strategy used, a follow-up inspection 10 to 21 days after extermination is advised to detect and manage a persistent infestation.42

All of the stages of bed bugs are visible, at least if you don't need reading glasses and you have a sufficient amount of light. So if you're looking closely enough, you can even see bugs in the nymphal first instar stage. A fecal spot, for its part, can be as large as a bed bug itself in terms of the area it covers. The spots are basically digested blood, so most are dark in color. On a white mattress, they stand out pretty well.
If you know that you have the bugs. Get sealing covers the kind that encloses completely, one for the mattress and one for the box spring. That will trap those critters inside and they will eventually die in there. Next you will need to decide of what combination of treatments you wish to use. Its a job that you will have to keep up with for some time. Do your research online first.
DIY approaches come with risk. It's not uncommon for someone to use a pest-control bomb or fogger that is available over the counter. These don't work well against bed bugs, according to research from Ohio State University. They can also expose people to toxic chemicals. Neither are over-the-counter aerosol insecticides effective against bed bugs. Most of these products have either pyrethrin or a pyrethroid as a main ingredient and those compounds have the same mode of action as DDT, which bed bugs have become resistant to. If you spray the bug directly you might kill it, but that is not going to get rid of the infestation. The problem is finding all the bed bugs. Some just can't be reached with insecticide. It's difficult for nonprofessionals to do anything more than kill what they can see, but that's just the tip of the iceberg in terms of what's there.
Bedbug bites, like all insect bites, can become infected through excessive scratching, as underneath the fingernails lies a host of bacterial pathogens. If your bites become infected, they will appear red and swollen, feel tender and may drain pus. Typically there will not be a fever unless a substantial area of the skin is involved. If you experience any of these symptoms, you must seek medical attention as it points to a secondary infection. Your physician may prescribe antibiotic therapy or, if the infection is mild, an antiseptic medication that you can buy without a prescription.[12][13][14]

The bites themselves don't usually pose any major health risk since bedbugs are not known to spread diseases, but an allergic reaction to the bites may require medical attention, CDC officials say. There have also been some strange cases linked to bedbug infestations. Researchers reported in the Canadian Medical Association Journal in 2009 that they treated a 60-year-old man for anemia caused by blood loss from bedbug bites. Another study published in 1991 in the Journal of the Egyptian Society of Parasitology found that people with asthma might be more susceptible to allergic reactions from bedbug bites.
Bed bugs are a traveler's nightmare. They can be picked up in hotel rooms, leaving red itchy bumps and possibly rashes to ruin your vacation. Or even worse: If you accidentally bring them back with you, they could infect your whole house. To prevent a plague of bed bugs, here are some tips of what to check while you're on the road and how to determine the symptoms of bed bug bites.
Bed bugs are active mainly at night. During the daytime, they prefer to hide close to where people sleep. Their flattened bodies enable them to fit into tiny crevices--especially those associated with mattresses, box springs, bed frames and headboards. Bed bugs do not have nests like ants or bees, but do tend to congregate in habitual hiding places. Characteristically, these areas are marked by dark spotting and staining, which is the dried excrement of the bugs. Also present will be hatched and un-hatched eggs, the tannish shed skins of maturing nymphs, and the bugs themselves. Another possible sign are rusty or reddish smears on bed sheets or mattresses from crushed engorged bed bugs. Although it’s often stated that bed bugs have a telltale “buggy” odor, the smell is seldom evident except in extreme infestations and should not be relied upon for detection.
Mix 8 ml (about 1/3 oz)(measurements on the bottle) or one 8 ml vial of Temprid FX with one gallon of water. Remember to use what you mix-within 24 hours. Adjust the spray pattern to a mist by turning the nozzle. A low fine mist is best for most spraying, but you may need to use a stream to get into some cracks and crevices. If you can't get into the cracks and crevices use one of the aerosols described below with it's crack and crevice tips to reach into these areas.
I prefer not to use chemicals because I have to breathe it in. Worse if you got kid and pets. As for the itch, try salt water.. works best if you didn’t start scratching. Keep the area cool to control the inflammation and itch with a wet paper towel. Then soothe with a generous amt of aloe get. Everyone reacted differently to the bed bug bites. Good luck.
Hi been getting bites since March. I have been to three doctors who all say the bites are not bed bug bites due to the pattern of the bites. This weekend I got bit again I have one on my leg and a two on my waistline. One of really big and the other are two small ones that are really red. I woke up in the middle of the night and saw a small bug on pillow and one on wall by bed and took a picture and from looking online looks like pic could be a bed bug or chigger. We have already checked the mattress a bunch and found no signs of bed bugs. Can I send you a pic so you can confirm what the bug might be?
Once an infestation is confirmed, an integrated pest management strategy should be employed. Promoted by the Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention, an integrated pest management strategy is a multi-faceted, comprehensive strategy that relies on knowledge of bedbug biology and habits, and the most up-to-date pest control methods.3 An integrated pest management strategy minimizes economic, environmental, and health hazards, and is most effective for small bedbug populations.
I have very small red bumps on only one hand. Most of them skin color a few red. They don’t hurt and if I scratch them they itch a little bit mostly I don’t even notice they are there. They aren’t really in a line but I have probably about 6 or so on the top of my hand only. I searched my bed and all around it I find no trace of anything. I did read up and find that some bed bugs affect people differently and don’t show up right away. I have been sleeping on this mattress for over a month now and this just started happening for about 3 weeks. Am I just being paranoid or you think it sounds like bed bugs at all
As bed bugs grow they molt, shedding their skin five times before reaching maturity. A blood meal is needed between each successive molt. Adult females also must feed in order to lay eggs. Under favorable conditions (70-80°F), the bugs can mature fully in as little as a month, producing multiple generations per year. Cooler temperatures or limited access to blood prolong the development time. 
In most cases, the only way to say for sure whether it was a bedbug that bit you is to search for evidence of bedbugs living in your home. "Once you start to notice the itchy bites, the second giveaway is the presence of small blood spots on your sheets or mattress, usually resembling patches of rust,” Durham says. Those spots are left behind after a bedbug has been smashed.
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