Many chemical pesticides are available, with more than 300 registered by the EPA. Pesticides should be applied to walls, floors, cracks in furniture, and seams and buttons of mattresses.21 The EPA’s Bed Bug Products search tool (Web site: http://cfpub.epa.gov/oppref/bedbug/) allows users to search by product name, company, EPA registration number, location of intended use, and pesticide type. The National Pesticide Information Center (Web site: http://npic.orst.edu/; telephone: 800-858-7378) is another useful resource. Silica gel dusts are a safer alternative to traditional pesticides, because they are less concentrated and less toxic.21 Plastic mattress and pillow encasements can help trap bedbugs and restrict spread.42 Regardless of the integrated pest management strategy used, a follow-up inspection 10 to 21 days after extermination is advised to detect and manage a persistent infestation.42
Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.