Bedbug bites, like all insect bites, can become infected through excessive scratching, as underneath the fingernails lies a host of bacterial pathogens. If your bites become infected, they will appear red and swollen, feel tender and may drain pus. Typically there will not be a fever unless a substantial area of the skin is involved. If you experience any of these symptoms, you must seek medical attention as it points to a secondary infection. Your physician may prescribe antibiotic therapy or, if the infection is mild, an antiseptic medication that you can buy without a prescription.[12][13][14]


Jump up ^ John Southall. "That soon after the Fire of London, in some of the new-built Houses they were observ'd to appear, and were never noted to have been seen in the old, tho' they were then so few, as to be little taken notice of; yet as they were only seen in Firr-Timber, 'twas conjectured they were then first brought to England in them; of which most of the new Houses were partly built, instead of the good Oak destroy'd in the old". A Treatise of Buggs [sic], pp. 16–17. Retrieved 1 December 2016.
Most bites will have a small clear area in the center surrounded by redness that may or may not be raised. People tend to become more sensitive and have larger reactions after each episode. Reactions can include itch, swelling, rash and wheals (large round red area on the skin). Severe reactions can cause skin blisters and trouble breathing, although these reactions are very rare. 
Scabies is a skin infestation of a type of mite known as Sarcoptes scabiei. These are tiny, almost invisible, eight-legged creatures that fall under the same class as spiders and ticks. Scabies mites burrow under the skin to lay eggs and will crawl around on the skin, causing intense itching. Once the eggs hatch, the larvae that emerge will burrow back into the skin, causing even more irritation.
First and foremost I think the wisest course of action to take is to get rid of your bed. the whole shebang…the mattress and box spring and all your linens, blankets, pillows and articles of clothing you use to lay in bed with (robes, pajamas and underwear). It’s just not worth it. Get a temporary air mattress for a few weeks if need be. You will be better off in the long run.
The significant resurgence of bedbugs in the past decade has been attributed to pesticide resistance, more frequent travel, lack of public awareness, and inadequate pest control programs. Bedbugs are obligate blood parasites (insect family Cimicidae). They can withstand a large range of temperatures but are attracted to warmth and carbon dioxide. They typically feed just before dawn. Cutaneous reactions to bedbug bites can include macules, papules, wheals, vesicles, bullae, and nodules. Bites may be confused with other skin conditions. Bedbug bite reactions are typically self-limited and resolve within one to two weeks without treatment. Bedbug infestation may cause significant psychological distress. The diagnosis of a bedbug infestation is based on history, appearance of bites, and inspection of sleeping quarters. Although there is no evidence that bedbugs transmit disease, systemic reactions may include asthma, angioedema, generalized urticaria, iron deficiency anemia, and, rarely, anaphylaxis. An integrated pest management strategy should be employed to eliminate infestation. Tactics include vacuuming, heat or cold treatment, trapping devices, and pesticides.
If possible get your treatment from a local outlet like Home Depot, a hardware store or an agricultural/farm supply store. If you can afford it get one of those steam mops like Shark has. It comes with a unit designed for hand steam treatments of the bed and the hot steam will kill the bugs. You will also need it if you have to treat carpeting. Professionals use a combination of treatments and you will too in order to be successful. Good luck!
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.
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