It is important to remember that they have a very flat body that allows it to hide almost anywhere. During the initial onset of the infestation, they are only visible around the tufts and seams of the mattress. As the infestation grows, these bugs spread out and inhabit larger and larger areas. Generally they prefer rough surfaces like wood or paper for their harborages.

I can definitely understand. This is has been going on with us for almost a year. My hands and arms look like I have leprocy or something. Horrible blisters, rash, scabs, and bunches of “bumps” especially in my right hand. I wind up with painful blood blisters some times. I am living on benedryl and calamine lotion. I hate going out because of what I look like. I have taken to using cover up and foundation on my hands to make the mess less noticable. i have a long-sleeved summer weight sweater that I wear whenever I do have to go out.
Individuals who experience repeated bites over time may have more pronounced symptoms. Some people may also develop scarring or a skin infection from intense scratching of the skin. Rarely, a more severe systemic allergic reaction to a bedbug bite may develop. Some individuals may develop insomnia and anxiety from serious or repeated bedbug infestations.
i found some thing that works i put a heavy blanket against the couch and then use itching cream called gold bond medicated cream use the maximum kind use it on every part u have been bitten do this for a while u will start to see a change the bites will start to go away slowly until they r all gone also make sure to wash where ever you have been bitten in cold water and use a lot of soap wash them good then use the medicated cream just some tips i have bed bugs and i have been bitten and it sucks it itches bad but i have found that this works!
If you have been bitten by bedbugs, the good news is that they aren't associated with any disease. You need only to avoid scratching the bites and getting a skin infection. Anti-itch creams may help. Treating your home or possessions to eliminate an infestation is more of a challenge, and you may need both nonchemical and chemical treatments. Learn how to treat your bites and get rid of bedbugs.

I sleeped over my boyfreinds house just for a night my 4month old daughter and I slept on the bed and we got bit bad but my poor baby seems to have pus on her bites..she got bit even on her face her fingers etc..but funny thing my boyfreind didnt get bit, I got home and i washed everything we took in hot water dried in hot washed my beeding all her blankets the car seat was left out in the heat for 2 days..then i washed it in hot water i vacumed the whole room sprayed alcohol on the carpet on my matress..question is what more can i do? is there any chance that they could still be in my room?
Once an infestation is confirmed, an integrated pest management strategy should be employed. Promoted by the Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention, an integrated pest management strategy is a multi-faceted, comprehensive strategy that relies on knowledge of bedbug biology and habits, and the most up-to-date pest control methods.3 An integrated pest management strategy minimizes economic, environmental, and health hazards, and is most effective for small bedbug populations.
Bed bugs usually bite people at night while they are sleeping. Hungry bed bugs may also feed during the daytime, especially if this is when the occupant normally sleeps. They feed by piercing the skin with an elongated beak through which they withdraw blood. Engorgement of the bed bug takes roughly three to 10 minutes, but because the bite is painless, the person seldom realizes they are being bitten. Bed bugs normally do not reside on people like head or body lice do; instead, immediately after feeding, bed bugs crawl to a secluded location to digest their meal. Symptoms after being bitten by bed bugs vary from person to person. Many develop an itchy red welt within a day or so of the bite. Others have little or no reaction. Sometimes the reaction is delayed days or even weeks after the actual bite occurs, which can make it difficult to determine where or when bites actually occurred. Studies conducted in bed bug-infested apartments suggest about 30 percent of people do not react even when bitten repeatedly over time, and there is still higher incidence of non-reactivity among the elderly. Unlike flea bites, which occur mainly around the lower legs and ankles, bed bugs feed on any skin exposed while sleeping (face, neck, shoulders, back, arms, legs, etc.). The welts and itching are often wrongly attributed to other causes, such as mosquitoes. For these reasons, infestations may go a long time unnoticed, and can become quite large before being detected. 
I use witch hazel with aloe vera (from Thayers). Apply with Q-tip or cotton ball. WORKS VERY WELL for me, especially when applied soon after bite is detected. Found that if it stings a bit when applied, it is likely that bite was recent, and more likely to reduce the itch. If I apply soon after a bite, I feel a little sting from the astringent, and the itch if often eliminated (although not sure how large the bugs are that bit me).
Since bed bugs can be found throughout the world, many people have suffered from their bites. Since you are reading this, you have also most likely been a victim but don’t worry, you are not alone. Their primary diet is blood, which makes humans their meal of choice, definitely not good news for us! Based on personal experience, they can leave a rather nasty, red mark which can itch like mad. No wonder people say “Goodnight and don’t let the bed bugs bite!” What do these bites look like (and what to do if you are bitten) and what are some ways that you can get rid of them?
The prognosis for bedbug bites is excellent. The vast majority of people who experience bedbug bites will recover without any long-term problems, and many individuals who are bitten may not exhibit any physical signs at all. However, the recent resurgence in bedbug infestations will require increasing public education and awareness, instituting effective preventive and control measures, and continuing research into the development of more effective, safe insecticides.

Bed bugs are active in summer and winter and are not considered "seasonal" in the same sense that mosquitoes, ticks and stinging insects are. Still, many consider bed bugs to be a greater problem in the warmer months, however it is not the bed bugs that are more active in the summer months - the humans are. In warmer weather we typically travel more, often sleeping in hotels and motels, using various modes of transportation, and thereby increasing our risk of exposure to bed bugs. The bed bugs themselves are year-round pests.
Before you run off and buy every cream the pharmacy stocks, you’ll want to confirm that the marks are actually from bed bugs. Even if they match the description – round, red marks that may bump, swell, itch, and/or burn – the marks could be allergic reactions to food or fabric, irritations from a rough material, or bites from another pest like mosquitoes or carpet beetles.
Data Sources: A PubMed search was completed in Clinical Queries using the key terms bedbug, rash, bites, and infestation. The search included meta-analyses, randomized controlled trials, clinical trials, case reports, and reviews. We also searched the online databases of the Environmental Protection Agency, Centers for Disease Control and Prevention, and Jefferson Clinical Images. Lastly, we used Essential Evidence Plus. Search dates: February through June 2011.
However, always remember that these simply treat the problem and do not get down to the root cause. You will still need to take steps to get rid of them! Here are a couple home remedies to get rid of bed bugs that have been extremely helpful to the community. I encourage you to take a look at that article if you are serious about removing them properly.
Scratching can cause superinfection, leading to impetigo, cellulitis, or folliculitis.27–32 Reactions typically resolve within one to two weeks without treatment.32 Systemic reactions have been described, including asthma, generalized urticaria, angioedema, iron deficiency anemia, and, very rarely, anaphylaxis.33–36 Although bedbugs have been suspected to be vectors of more than 40 microorganisms, there is no evidence that they are involved in the transmission of disease.5
First, there should be a thorough inspection of areas that may be infested to identify bedbugs. Once a room is identified as infested, don't remove anything from the room unless it is sealed in a plastic bag. Furniture and items that you want to discard rather than treat should be bagged and destroyed so other people don't use them. Call your trash collection agency to arrange for an immediate pickup. Reduce the clutter in the room and discard any cardboard boxes as they can harbor bedbugs. Vacuum the area and seal the vacuum bag in a plastic bag and discard it.
Just because you can't see bed bugs, does not mean that they are not still there. Bed bugs are rarely seen in the day, out in the open or on the surface of beds or chairs. They have been described as champions of hide-and-seek. So, it is not uncommon to miss the bed bugs altogether. Bed bugs love to hide in the cracks and crevices associated with mattresses, cushions, bed frames and other structures, which is why it is very important to look for telltale symptoms of bed bugs and signs of an infestation, such as shed skins and specks of blood or feces on linens, furniture, mattresses and other areas where the bugs might be hiding.
Amazingly, these sneaky little bloodsuckers dine on you without waking you. You don't feel their stealthy bite because they inject a numbing agent into your body, along with an anticoagulant to keep your blood flowing as they suck. The first sign of bedbugs may be itchy, red bites on the skin, usually on the arms or shoulders. Bedbugs tend to leave straight rows of bites.
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