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When people are bitten, they often do not notice at first. It’s a possibility that one reason could be that these blood sucking insects feed late in the night, before the breaking of dawn. Humans are often in a deep REM sleep during that time. Upon arising, individuals can find bite marks; however it can take up to ten days for adverse or allergic reactions to develop.
Bedbugs reproduce by a gruesome strategy appropriately named "traumatic insemination," in which the male stabs the female's abdomen and injects sperm into the wound. During their life cycle, females can lay more than 200 eggs, which hatch and go through five immature "nymph" stages before reaching their adult form, molting after each phase. [Infographic: Bedbugs: The Life of a Mini-Monster]
The first sign of a bed bug problem is obvious: the bed. After bed bugs feed on humans, they'll leave behind blood stains resembling small rust spots. These will usually be found near the corners and edges of the bed. Bed bugs also shed their skin, or molt, several times as they mature, so you may find their oval brown exoskeletons during your search.
Some people experience anxiety, sleeplessness and unease as symptoms of having had bed bugs. Let's face it, bed bug infestations are understandably significant psychosocial stressors, and some people may experience sleeplessness as they worry about bugs biting them or their family members. Not surprisingly, people have been known to self-isolate, avoiding family and friends out of concern for spreading the infestation, or (if word gets out that they have bed bugs) they may be avoided by friends or others in the community, or find they have problems at work.  As a result, victims of bed bug infestations may experience moderate to severe levels of stress, anxiety and depression. In severe cases, these persons should seek counseling and treatment as required.
I am apparently allergic to these things. My bites swell to huge sizes and I get red marks running up my arms and it itches like crazy, almost like a burning itch. However, doing some research I found an effective way to stop the itch. Its not for everyone, but for someone like me who can’t even touch the shells (my fingers have gotten swollen searching for the damn things), this works for me. Again, not for everyone:
Also, we do have pets and a 10 year old living with us as well. 3 cats and a dog. They have been fine with the bleach smell, though it seems to be making one of my cats a little wild. A suggestion I have, if you try what we’re trying, is put the animals up until the KABOOM has dried, because, where as our animals are seemingly okay, it could still harm them. Luckily our cats are indoor/outdoor cats, so we can put them outside while we do it.
Bed bugs will also succumb to cold temperatures below 32°F, but the freezing temperatures must be maintained for a longer period (e.g., one to two weeks). Consequently, heating tends to be a better option throughout much of the country. Efforts to rid entire dwellings of bed bugs by raising or lowering the thermostat will be unsuccessful, although pest control firms are able to achieve lethal temperatures with supplemental heaters (see the subsequent section entitled "Heat Treatments" for more details). 

Reactions to bed bug bites differ from person to person from none to a full-blown allergic reaction. A mild reaction may reveal flat, red bumps at the bite sites. A more severe reaction may include an irritating itch (as in my case), or swelling. Resisting the itch is incredibly difficult, but giving in to it can cause severe irritation to the skin, increasing your risk for an infection. It’s the chemicals in the bed bug’s saliva that trigger such reactions, some lasting more than two weeks.

I am trying to type this and get relief at the same time from the terrible itching that has robbed me of my sleep for several nights now….Anyway, now as I said, my new recliner is ruined because even after covering it with plastic and then covering with a new sheet I just took out of the package, it still was stained with vaseline I had put on my arms from all the bites and itching I’m going through…I also resorted to covering it with corn starch which seems to brush right off, but I’m afraid the vaseline is here to stay…I’m heartbroken about my recliner and the whole mess in general!!
Pay attention to when the bites occur. Consider, for example, if you notice the bites after waking up when previously you hadn't noticed them. However, this can also be difficult to determine because each person's reaction time can vary significantly. Symptoms that result from the bite can manifest at any point from a couple of hours to more than a week after the bite occurred.

Hello all I just want to put this out there that heat is the best way to kill these little pests. I work for a company that uses heat to do structural pasteurization, in other words we heat the entire house up to 140°+ (which is higher than the the thermal kill point for bedbugs) for an hour or more (though they can only withstand that heat for less than 15 min) This has been the ONLY way to kill them with a 100% success rate since they are becoming resistant to chemicals and DDT is illegal. Some things work for some infestations but not for all, there are a lot of good ideas on here :-)
In addition to the physical manifestations of bedbug bites, patients can experience significant psychological distress. The stigma that bedbugs are related to poor hygiene (however inaccurate) can lead to poor self-esteem, avoidance of family and friends, and suspension from work.37–39 Management of an infestation can be stressful, costly, and disruptive to everyday life. Worry can lead to insomnia, depression, anxiety, and even delusional parasitosis.37

i just recently stayed at the A-1 Motel and our bed had bed bugs. i really want to get rid of these bites because they itch so bad. i have them all over both my arms, legs, neck, back, and my stomach. i want to get rid of them so i can go out in public without having to be embarrassed over them. i will try the baking soda and water thing and i hope it will work.
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.
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