No two people react to bites in the same way, although some reactions are similar. Because of the saliva that they leave behind, the first reaction is usually severe itching and irritation. This is often followed by a raised appearance on the contacted area. Some people, however, react by having welts and hives all over the body. Still others will have small, pinkish bumps that are concentrated in one area.
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.