The exact causes of this resurgence remain unclear; it is variously ascribed to greater foreign travel, increased immigration from the developing world to the developed world, more frequent exchange of second-hand furnishings among homes, a greater focus on control of other pests, resulting in neglect of bed bug countermeasures, and increasing resistance to pesticides.[4][38] Declines in household cockroach populations that have resulted from the use of insecticides effective against this major bed bug predator have aided the bed bugs' resurgence, as have bans on DDT and other potent pesticides.[39][medical citation needed]
Insect and spider bites and how to deal with them Insect and spider bites can occur almost unnoticed, or they can be painful. Either way, home treatment is usually enough for most symptoms. However, some bites can spread serious disease, such as Lyme disease and malaria. Find out how to protect against bites and what to do if someone has a severe reaction to a bite. Read now
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If you suspect an infestation, experts recommend finding a professional exterminator who has experience dealing with bedbugs. Sprayed insecticides are commonly used to treat infestations, and exterminators may also use nonchemical methods, such as devices to heat a room above 122 degrees Fahrenheit (50 degrees Celsius), a lethal temperature for bedbugs, according to the Mayo Clinic. Freezing infested items for a few days at temperatures below 0 F (-18 C) may also put bedbugs to permanent rest, according to the University of Minnesota. But you may have to throw out heavily infested mattresses and other items of furniture.
I’ve encountered mosquito bites, flea bites and spider bites, but never had I encountered bed bug bites, that is until I travelled to San Francisco, CA. I made the trip at least four times a year; however, this time was different—opting to stay in a nearby hotel instead of with family or friends. I remember lying in bed. The room was hot and stuffy, causing me to toss and turn throughout the night. When morning came, I was exhausted but began my usual morning routine eager to get on the road. After a quick rinse, I dragged myself over to the mirror; that’s when I noticed them—little red bumps across my chest. Quickly, I scurried over to the bed—pulling off sheets, flipping pillows, inspecting the mattress and the box spring—nothing! Ugh, how could this have happened? It was a top-rated hotel. Were these bed bug bites, or was it another blood-sucking insect?
Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).
Mechanical approaches, such as vacuuming up the insects and heat-treating or wrapping mattresses, are effective.[3][6] An hour at a temperature of 45 °C (113 °F) or over, or two hours at less than −17 °C (1 °F) kills them.[6] This may include a domestic clothes drier for fabric or a commercial steamer. Bed bugs and their eggs will die on contact when exposed to surface temperatures above 180 degrees and a steamer can reach well above 230 degrees.[31][15] A study found 100% mortality rates for bed bugs exposed to temperatures greater than 50 °C (122 °F) for more than 2 minutes. The study recommended maintaining temperatures of above 48 °C for more than 20 min to effectively kill all life stages of bed bugs, and because in practice treatment times of 6 to 8 hours are used to account for cracks and indoor clutter.[32] This method is expensive and has caused fires.[6][15] Starving them is not effective as they can survive without eating for 100 to 300 days, depending on temperature.[6] One expert recommends not trying to get rid of bed bugs exclusively on one's own.[29]
There are thousands of types of spiders (technically arachnids and not insects) crawling around the U.S., but only two of them–the black widow and the brown recluse–can cause serious problems, and even those are rare. Most of the time you’ll see red bumps that hurt and itch if you’re bitten by a spider. Very few people get the severe pain and cramping of a widow bite or the decaying ulcers of a recluse bite (although if you do, get medical help right away).
The diagnosis of a bedbug infestation should be based on the clinical history and appearance of bites. A thorough inspection of sleeping quarters by the patient, a family member, or a pest control expert may demonstrate the telltale signs of an infestation15 (i.e., specks of blood-tinged insect feces and exoskeleton casts [Figure 5]). With the aid of a magnifying glass, special attention should be given to cracks and crevices of furniture, baseboards, electrical boxes, curtains, carpet, luggage, bed frames and headboards, picture frames, wall hangings, mattress and box spring seams, peeling wall paper, clothes, and linens.37 Live bedbugs can sometimes be caught by turning on a flashlight just before dawn, when bedbugs are most active, larger in appearance, and slower to scatter because of recent feeding.40
Bed bug bites typically appear in groups of three, called the "breakfast, lunch, and dinner" pattern. Each victim's reaction to bed bug bites is unique. Some may have a slight reddening of the skin. Others may have a more severe reaction, causing a raised, itchy rash. A raised rash may obscure the individual bites, making it challenging to identify. Sometimes, bites and lesions can throb and become very painful for days after the bugs bit you.
We took a road trip with our kids, stayed in a nice hotel and guess what? Bed bug bites on all of us. I usually carry a product with us as it works on insect bites so we decided to try it… thank goodness it worked and got rid of the pain and itching quickly… i ordered it from a website but soon found out that I could do the same thing with baking soda and water as mentioned on this site. Before you buy, consider the alternatives! Thanks and good luck to everyone!
All these bed bugs can be dealt with. it is best to use a non chemical treatment to make it safe for your environment . here is one i found, food grade Diatomaceous Earth found at garden centers, follow instructions, and move beds away from the walls, sprinkle in the carpet deeply, on to base boards , ( it works like borax powder for fleas and roaches) .

Application entails treating all areas where the bugs are found or tend to hide or crawl. This takes considerable effort and follow-ups are usually needed. Companies typically treat seams, folds and crevices of bed components, chairs and sofas, but usually will not spray the entire sleeping surface or seating area. They also do not spray bed sheets, blankets or clothing, which instead should be hot washed or heated in a dryer. 
Hi there! Honestly, if you have checked properly (like really well) and you don’t see any signs of bed bugs, it might be another insect. Unfortunately, there are so many little insects that could be biting you (such as fleas, etc.) but maybe start with giving all your laundry a good hot wash. Once that is done, see if you continue getting the bites and then we can investigate. Good luck, if you appreciated my help, please share my blog with your friends and family.
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.