Medical treatment is usually not needed for bedbug bites. If required, medical treatment is aimed at relieving the symptoms (like itching) caused by bedbug bites. In the rare cases of a systemic allergic reaction or a secondary skin infection, evaluation by a health care professional may be necessary. Individuals may also want to seek medical care if they are unsure of what is causing their skin lesions.

Bed bugs often hide in seams, folds and crevices of mattresses, box springs, bed frames and headboards. A thorough inspection requires dismantling the bed so that upper and lower seams and surfaces can be examined. Things to look for are the bugs themselves, shed skins of the nymphs (immature bed bugs), and the blackish fecal spots. The dark spots of dried bed bug excrement are often present along mattress seams or wherever the bugs have resided. Box springs afford many places for bed bugs to hide, especially along the upper seams and underneath, where the bottom edge of the box rests on the frame. If an underlying dust cover is present, it may have to be removed to gain access for inspection and possible treatment. Successful treatment of mattresses and box springs can be difficult, however, and infested ones may need to be discarded or encased in a protective cover. 
Thank God I don’t have to replace any of my furniture yet or I wouldn’t know what I would do, because my income is limited also…if the landlords were more cooperative in dealing with this the problem of bed bugs wouldn’t be a problem….I read something about bed frame posts to put on each foot of the bed and it keeps the bugs from entering your bed…also to use at least 5lbs. of Diatomaceous earth or perma guard, it’s a safe powder substance you spread all over your house, on rugs, cracks foundations etc. and this seems to kill them you leave it down for a few days..the cost is minimal as low as $10.00- $15.00. Well worth the investment, you can purchase it online, EBay or your local feed and supply store.

Symptoms may not appear until some days after the bites have occurred.[5] Reactions often become more brisk after multiple bites due to possible sensitization to the salivary proteins of the bed bug.[3] The skin reaction usually occurs in the area of the bite which is most commonly the arms, shoulders and legs as they are more frequently exposed at night.[5] Numerous bites may lead to an erythematous rash or urticaria.[5]
Jump up ^ John Southall. "That soon after the Fire of London, in some of the new-built Houses they were observ'd to appear, and were never noted to have been seen in the old, tho' they were then so few, as to be little taken notice of; yet as they were only seen in Firr-Timber, 'twas conjectured they were then first brought to England in them; of which most of the new Houses were partly built, instead of the good Oak destroy'd in the old". A Treatise of Buggs [sic], pp. 16–17. Retrieved 1 December 2016.
Bed bug bites occur most frequently while you’re asleep. As bed bugs bite they inject their victims with an anesthetic (as well as an anticoagulant), numbing the area and making it very rare for someone to wake up when bitten. Bites normally take a day or two to appear, although depending on your individual reaction they may be more visible sooner.

Since bed bugs can be found throughout the world, many people have suffered from their bites. Since you are reading this, you have also most likely been a victim but don’t worry, you are not alone. Their primary diet is blood, which makes humans their meal of choice, definitely not good news for us! Based on personal experience, they can leave a rather nasty, red mark which can itch like mad. No wonder people say “Goodnight and don’t let the bed bugs bite!” What do these bites look like (and what to do if you are bitten) and what are some ways that you can get rid of them?
1. Mattress Safe Encasements: Mattress Safe Products are bed encasements to place over your mattress or boxspring so you don't have to throw them away. They are bedbug certified. If using a labeled insecticide on the mattress or boxspring first, apply on mattress or box springs then zip it up. It has a patented hook to keep the bed bugs inside the encasement so they cannot escape. Keep the encasement in place for one year (due to bed bug life cycles).
Bed bugs hide in seams of mattresses, box springs, bed frames, headboards, dresser tables, inside cracks or crevices, behind wallpaper, or any other clutter or objects around a bed during the day. Bed bugs are transmitted from place to place as people travel. They can be in the seams and folds of luggage, overnight bags, folded clothes, bedding, furniture, or anywhere else they find a place to hide.
Bed bugs can result in a number of health effects including skin rashes, psychological effects and allergic symptoms.[5] Bed bug bites may lead to skin changes ranging from non visible to prominent blisters.[1] Symptoms may take between minutes to days to appear.[2] Itchiness is common, while some may feel tired or have a fever.[2] Typically uncovered areas of the body are affected.[2] Classically three bites occur in a row.[2] Bed bugs bites are not known to transmit any infectious disease.[5][7]

Until fairly recently, most people (and even pest control professionals) had never seen a bed bug. Bed bug infestations actually used to be very common in the United States before World War II. But with improvements in hygiene, and especially the widespread use of DDT during the 1940s and ‘50s, the bed bugs all but vanished. The pests persisted, however, in some areas of the world including parts of Africa, Asia, and Eastern Europe. Over roughly the past decade, bed bugs have made a dramatic comeback in the U.S.― they’re appearing increasingly in homes, apartments, hotels, health care facilities, dormitories, shelters, schools and public transportation. Other places where bed bugs sometimes occur include movie theaters, laundries, rental furniture, and office buildings. Immigration and international travel have contributed to the resurgence of bed bugs in the U.S. Changes in modern pest control practice, less effective insecticides ― and a decrease in societal vigilance ― are other factors suspected for the recurrence. 
Data Sources: A PubMed search was completed in Clinical Queries using the key terms bedbug, rash, bites, and infestation. The search included meta-analyses, randomized controlled trials, clinical trials, case reports, and reviews. We also searched the online databases of the Environmental Protection Agency, Centers for Disease Control and Prevention, and Jefferson Clinical Images. Lastly, we used Essential Evidence Plus. Search dates: February through June 2011.
These nocturnal creatures can hide in beds, floors, furniture, wood, and paper trash during the day. We humans usually become their dinner during the night, with peak biting activity just before dawn.They can obtain their meal in as little as three minutes, after which they are engorged and drop off the host, then crawl into a hiding place to digest their meal. Bedbugs can live for 10 months, and can go weeks without feeding.
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