Cutaneous reactions to bedbug bites can vary widely and are easily confused with other conditions (Table 1).15–19 A typical lesion is a 2- to 20-mm, pruritic, erythematous maculopapule with a central hemorrhagic crust or vesicle.5,8 Macules, papules, wheals (Figure 3), vesicles, bullae, and nodules have all been reported,20 as have asymptomatic lesions with a barely visible punctum as the only evidence of a bite.8 Bites vary in number and are preferentially distributed in unclothed areas (e.g., face, neck, extremities). Unlike many other arthropod and insect bites, bedbug bites are rarely located in the popliteal fossae or axillae.21 Lesions can be noticeable immediately when waking up or several days later, with the reaction often progressing from delayed to immediate with subsequent exposures22–26  (Table 2). The classic bedbug rash is referred to as “breakfast, lunch, and dinner” because it commonly presents as several bites in a row or cluster 20 (Figure 4).
Great stuff to use. My former girlfriend gave me a parting gift of bedbugs she got while staying at her parents house. She was good enough to leave me some cortisone though which I needed for the first time this morning. I had being seeing bedbugs and routinely treating them for about 2 months and I had laid diatomaceaous earth around my bed and didn’t have any itching or real issues. The layer had been wearing thin and I was too lazy to respreads. Last night I slept in the nude and woke up with the worst itching and now a rash all over my body. I had been seeing bedbugs and killing them for a month or two on and off and thought what’s the big deal. Now if know!!! This is the worst case of itching I’ve ever experienced!! Luckily I have the cortisone but it’s not helping too much. I’m blasting off a bed bug bomb my brother gave me 2 months ago that I never used and respreading the diamo earth. I checked my mattress and found literally only 2 bugs a very small nymph and an adult but they must be somewhere else because my body is covered in a rash. Maybe I finally reacted to bites I had been getting in the past or more are hiding elsewhere but I’m going to rid myself of these pests. Wish I could rid the world of them!!! This itching is the worst!!

First and foremost I think the wisest course of action to take is to get rid of your bed. the whole shebang…the mattress and box spring and all your linens, blankets, pillows and articles of clothing you use to lay in bed with (robes, pajamas and underwear). It’s just not worth it. Get a temporary air mattress for a few weeks if need be. You will be better off in the long run.


Flea bites are caused by the parasitic insect, the flea. The most common species of flea in the US is the cat flea, Ctenocephalides felis. Signs and symptoms of flea bites in humans include itching, hives, a rash with bumps, red spots with a "halo," and swelling around the bite. Treatment for flea bites includes over-the-counter medicine and natural and home remedies to relieve and soothe itching and inflammation. The redness of a flea bite can last from a few hours to a several days.
Never treat any bedding, mattress, etc. with anything other than the treatments listed: borax, enzyme cleaner, Comet, sodium borate. Other pesticides and exterminating fluids can be harmful to humans. Even so, bedding and mattresses treated with chemicals such as borax or Comet should be left outside to dry naturally in the sun, then wrapped in plastic before next use, so as not to irritate the skin.
Very helpful article, plus everyone’s comments. I wish you all the best of luck with bedbug problems. We went to a cabin near Yosemite before Christmas and I saw bugs on the bed. Luckily we didn’t sleep there and left right away. However I’m afraid some came home with us. About 3 weeks after our trip, I got a rash on my neck, but it’s not very itchy. Haven’t seen any bugs at home, but am worried. Will try the tips in the article–any suggestions how to heat a bedroom to 120 degrees?
Most people will find bed bug bites to be small and very itchy. These bites are often mistaken for something else such as eczema. It can be hard to diagnose bed bug bites due to this, especially if someone inflames their skin further by scratching the area. There are some signs that point more strongly to bed bugs over other types of bugs. The number one thing to look out for is a line of bites going straight up your body: bed bugs commonly bite in this pattern as they bite you at the crease where your body meets the bed sheets. It’s very rare to find a single bite like you would with spiders or mosquitoes, and much more common to find clusters and lines. It’s also rare for bugs to bite your face. They most frequently bite your lower body, but anywhere can be bitten.
Bedbugs are small, flat, wingless insects with six legs that, like mosquitoes, feed on blood from animals or people. They range in color from almost white to brown, but they turn rusty red after feeding. The common bedbug doesn't grow much longer than 0.2 inches (0.5 centimeters) and can be seen by the naked eye to the astute observer.  Bedbugs get their name because they like to hide in bedding and mattresses.
×