If you know that you have the bugs. Get sealing covers the kind that encloses completely, one for the mattress and one for the box spring. That will trap those critters inside and they will eventually die in there. Next you will need to decide of what combination of treatments you wish to use. Its a job that you will have to keep up with for some time. Do your research online first.
Heat treatment: Heat of 120 F for two hours will kill bedbugs. Wash items in hot water (120 F or above). This may not be enough, though, so it's recommended that you place items in a clothes dryer on hot heat for at least 30 minutes. In a hot climate, you can bag items in a black plastic bag and leave them in direct sunlight for 24 hours. For travel or home use, there are portable heating units that can be used for clothing and luggage. A garment steamer can also be used on some items, such as luggage.

Application entails treating all areas where the bugs are found or tend to hide or crawl. This takes considerable effort and follow-ups are usually needed. Companies typically treat seams, folds and crevices of bed components, chairs and sofas, but usually will not spray the entire sleeping surface or seating area. They also do not spray bed sheets, blankets or clothing, which instead should be hot washed or heated in a dryer. 
My husband works for a garbage company (this is how we think the invasion started) and at the moment they are localized to our bedroom and our bathroom. However, the first place we found them was in our headboard & footboard. It is wood with an intricate carving. We checked the mattress and box spring and didn’t find a thing. But they LOVE that wood.
i just recently stayed at the A-1 Motel and our bed had bed bugs. i really want to get rid of these bites because they itch so bad. i have them all over both my arms, legs, neck, back, and my stomach. i want to get rid of them so i can go out in public without having to be embarrassed over them. i will try the baking soda and water thing and i hope it will work.
When staying in a hotel, I check the bed before I bring the suitcase into the sleeping part of the room so that if I have to ask the manager for another room, then I haven't exposed my suitcase to the bugs. When settling in, I put my suitcase up on the suitcase stand or the desktop so that any bugs are less likely to crawl into it. An extreme measure would be putting the suitcase in the tub. If it's a porcelain tub, bed bugs would have a hard time crawling up it. It's also unlikely that they would randomly crawl up a tub, because it's not near the bed. But if I don't see bed bugs in the room when I inspect it, I just put my suitcase on the stand because I know the probability is really low that a bug is going to crawl up the stand and into my suitcase. I keep my clothes in the suitcase or hang them in the closet—I don't leave them on the floor because wandering bed bugs might crawl into them.
Hello! Almost overnight I have had a series of small bumps appear on my chest. These bumps look like pimples and they don’t itch at all. I had bed bugs well over a year ago and once they were treated I never saw anything except these bumps recently. My sister thinks I’m just being paranoid because we’ve both checked the bed and saw no signs. And because my chest is always covered, but my arms and legs that are are exposed never have places. I realize that I’m probably being paranoid, but I just wanted an outside opinion.
Went on vacation with my husband, just 3 weeks ago. Stayed at a motel in Daytona. Had a double bed. Slept with my husband the first night, we did not go under the cover. The next night slept in the other bed, went under the cover and low and behold felt something biting me in the middle of the night, so I went on top of the cover for the rest of the night. Told my husband about it when we awoke.
Probably chiggers -- they are very small, red mites that usually cannot be seen with the naked eye. They are about as small as the period at the end of this sentence. To stop the itching, use OraJel (usually sold for teething babies), which contains benzocaine (an anesthetic). Also, rub in hydrocortisone cream. To prevent chigger bites, wear long pants and stuff the cuffs into your socks.

Just because you can't see bed bugs, does not mean that they are not still there. Bed bugs are rarely seen in the day, out in the open or on the surface of beds or chairs. They have been described as champions of hide-and-seek. So, it is not uncommon to miss the bed bugs altogether. Bed bugs love to hide in the cracks and crevices associated with mattresses, cushions, bed frames and other structures, which is why it is very important to look for telltale symptoms of bed bugs and signs of an infestation, such as shed skins and specks of blood or feces on linens, furniture, mattresses and other areas where the bugs might be hiding.
I thought I was getting bitten by mosquitoes when out on my balcony. But I get bitten during the night and basically on the arm outside of the covers. This all started after my neighbors in the apartment next door moved out. I have yet to actually see the bugs. The bites tend to be in a line which I read online was typical for bedbugs but not always.
Spray all baseboards, loose plaster, behind bed frames and headboards, beneath beds and furniture, and bedsprings and bed frames. Do not apply to furniture surfaces or mattresses where people will be laying or sitting unless using a product labeled for that type of treatment. Infested bedding should not be treated, but should be removed, placed in sealed plastic bags, and taken for laundering and drying at high temperature.
Mix 3 oz per gallon or 0.75 oz per quart and spray with a low pressure sprayer into the areas where the bed bugs are hiding. Typical areas include bed frames, headboards, under beds, baseboards, moldings, behind pictures,etc. Remember to apply in the joints and crevices of furniture. If the crack and crevice is too small, use an aerosol with a crack and crevice tip (recommendations are below.)
Also, we do have pets and a 10 year old living with us as well. 3 cats and a dog. They have been fine with the bleach smell, though it seems to be making one of my cats a little wild. A suggestion I have, if you try what we’re trying, is put the animals up until the KABOOM has dried, because, where as our animals are seemingly okay, it could still harm them. Luckily our cats are indoor/outdoor cats, so we can put them outside while we do it.
But the bites will look different from person to person, and some people won’t develop any reaction whatsoever. “The same bedbug could bite two different people and one could have no reaction at all and the other can have an extreme reaction with a swollen arm or itchy rash,” says Eric Braun, a board-certified entomologist and business manager for the national pest control company Rentokil Steritech, who is based in Redding, Pennsylvania. Some people end up developing a rash that looks like eczema. (5)
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