First, there should be a thorough inspection of areas that may be infested to identify bedbugs. Once a room is identified as infested, don't remove anything from the room unless it is sealed in a plastic bag. Furniture and items that you want to discard rather than treat should be bagged and destroyed so other people don't use them. Call your trash collection agency to arrange for an immediate pickup. Reduce the clutter in the room and discard any cardboard boxes as they can harbor bedbugs. Vacuum the area and seal the vacuum bag in a plastic bag and discard it.
Bed bug bites are caused primarily by two species of insects: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] They are about 1 to 7 mm in size.[7] Spread is by the bugs walking between nearby locations or being carried within personal items.[2] Infestation is rarely due to a lack of hygiene but is more common in high density areas.[8][2] Diagnosis involves both finding the bugs and the occurrence of compatible symptoms.[5] Bed bugs spend much of their time in dark locations like mattress seams or cracks in the wall.[2]
Bedbug bites may go unnoticed or be mistaken for flea or mosquito bites or other types of rash or skin conditions, since the signs of bedbug bites are difficult to distinguish from other bites or skin conditions. Bedbugs also have glands whose secretions may leave musty odors, and they also may leave dark fecal spots on bed sheets and around places where they hide (in crevices or protected areas around the bed or anywhere in the room).
Recently I went to Dubai, I stayed at my husband’s rental furnished flat. The next morning I was covered with bites. Immediately I knew its big bites but don’t know it’s bed bugs until I google search online a few days. I was so allergic to the bites & can’t stop scratching them. At last I went to a local pharmacy and got this ‘Fenistil Gel’ AKA Dimetindene maleate. it works really well. My bites stop itching, swelling reduced. Some bites I need to applied the gel 1-2 times a day then it stopped bothering me. The only problem now is the marks never go away. :(
Very helpful article, plus everyone’s comments. I wish you all the best of luck with bedbug problems. We went to a cabin near Yosemite before Christmas and I saw bugs on the bed. Luckily we didn’t sleep there and left right away. However I’m afraid some came home with us. About 3 weeks after our trip, I got a rash on my neck, but it’s not very itchy. Haven’t seen any bugs at home, but am worried. Will try the tips in the article–any suggestions how to heat a bedroom to 120 degrees?
I’ve cleaned the entire area…this time sprayed it all down with a bedbug killing spray (Raid). Everything, nooks, crannies, corners, the vent. I’ve also re-inspected my spare mattress. No sign of anything. I’ve gone as far as going into both. the inside of my boxspring has been saturated with the raid spray as is the “down” side of the mattress. I slashed into the side of the mattress and sprayed inside there too. I am going to be mopping with bleach in the morning and afterward I will do my spray down again.
To reduce the effects of swelling and rashes, you could take an over-the-counter antihistamine, which is usually in the form of an oral pill. Be sure to check the product label for possible side effects, though: some may cause drowsiness, dizziness, irritability, and vision changes, ringing in the ears, and other disrupting symptoms. You’ll want to be careful about taking these pills if you’re going to be driving or operating heavy machinery, and you definitely want to talk to your doctor first if you’re pregnant or have high blood pressure.
Some pest control firms utilize specialized heating equipment to de-infest furnishings, rooms, and entire dwellings. The procedure involves heating up the infested item or area to temperatures lethal to bed bugs. Portable heaters and fans are used to gradually heat the air to about 120 - 130°F while monitoring with strategically placed sensors. By carefully controlling the temperature, bugs and eggs are killed wherever they may be without damaging household items. 
If you arrive home and discover that you have brought some unwanted guests home with you, immediately notify the hotel of your discovery. Having a possible infestation in hotels and motels can be a public relations nightmare for the owners. Politely ask them to pay for any and all costs incurred to rid your clothing and home of a possible new infestation.
Aerosols (D-Fense NXT, Crossfire Aerosol, or Bedlam Plus) Usage: Simply attach the plastic tip to the aerosol can. Apply as a crack and crevice or spot treatment where evidence of bed bugs occurs. This includes bed frames, box springs, inside empty dressers, clothes closets, curtain rods, hollow spaces, carpet edges, high and low wall moldings and wallpaper edges.

The bites themselves don't usually pose any major health risk since bedbugs are not known to spread diseases, but an allergic reaction to the bites may require medical attention, CDC officials say. There have also been some strange cases linked to bedbug infestations. Researchers reported in the Canadian Medical Association Journal in 2009 that they treated a 60-year-old man for anemia caused by blood loss from bedbug bites. Another study published in 1991 in the Journal of the Egyptian Society of Parasitology found that people with asthma might be more susceptible to allergic reactions from bedbug bites.

Bedbugs are most often found in hotels, hostels, shelters, and apartment complexes where lots of people come and go. Because bedbugs hide in small crevices, they can hitch a ride into your home on luggage, pets, furniture, clothing, boxes, and other objects. Bedbugs are found worldwide, but are most common in developing countries. Once rare in North America, they may be on the rise due, in part, to increases in international travel.
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