First and foremost I think the wisest course of action to take is to get rid of your bed. the whole shebang…the mattress and box spring and all your linens, blankets, pillows and articles of clothing you use to lay in bed with (robes, pajamas and underwear). It’s just not worth it. Get a temporary air mattress for a few weeks if need be. You will be better off in the long run.

Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 

However, low-level infestations are also much more challenging to find and correctly identify. Other insects, such as carpet beetles, can be easily mistaken for bed bugs. If you misidentify a bed bug infestation, it gives the bugs more time to spread to other areas of the house or hitchhike a ride to someone else's house to start a new infestation. Learn about identifying bed bugs.

Jump up ^ Anderson, J. F.; Ferrandino, F. J.; McKnight, S.; Nolen, J.; Miller, J. (2009). "A carbon dioxide, heat and chemical lure trap for the bed bug, Cimex lectularius" (PDF). Medical and Veterinary Entomology. 23 (2): 99–105. doi:10.1111/j.1365-2915.2008.00790.x. PMID 19499616. Archived (PDF) from the original on 16 August 2017. Retrieved 27 May 2010.
Bed bugs are attracted to their hosts primarily by carbon dioxide, secondarily by warmth, and also by certain chemicals.[4][16][17][18] Cimex lectularius only feeds every five to seven days, which suggests that it does not spend the majority of its life searching for a host. When a bed bug is starved, it leaves its shelter and searches for a host. It returns to its shelter after successful feeding or if it encounters exposure to light.[19] Cimex lectularius aggregate under all life stages and mating conditions. Bed bugs may choose to aggregate because of predation, resistance to desiccation, and more opportunities to find a mate. Airborne pheromones are responsible for aggregations.[20]
A few decades ago, bedbugs were somewhat of a novelty in developed countries. But since the early 2000s, infestations have become more common in places like the United States, Canada, the United Kingdom and Europe, according to the U.S. Centers for Disease Control and Prevention (CDC). A 2013 study in the journal Nature Scientific Reports suggested that bedbugs have evolved ways to resist insecticides.
Bites on dogs and cats will look much like bites on people, and the pet owner may actually suspect a mosquito or flea bit the pet. As with people, bed bugs do not stay on pets, but return to a protected harborage site after feeding. In addition to bites, the presence of the bug’s feces, cast skins and the animal’s irritation at night are also indicators of bed bugs biting pets. Therefore, one of the best things to do is inspect the pet’s bedding and frequently groom the animal while being vigilant for the telltale signs of bed bug presence.
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