While cleaning up infested areas will be helpful in controlling bedbugs, getting rid of them usually requires chemical treatments. Because treating your bed and bedroom with insecticides can be harmful, it is important to use products that can be used safely in bedrooms. Do not treat mattresses and bedding unless the label specifically says you can use them on bedding.
I have no idea what works…. all the benedryl, cortizone, calamine lotion, and any cream/ointment said that they help with insect bites DOES NOT work. Once you start scratching, it’s over, you are going to scratch until the cows come home. If I am able to the trick is not to scratch at all. The enzyme is only released when you scratch, unless you are highly allergic like the picture that is show above, and I thought I was allergic, guess not.
Just because you can't see bed bugs, does not mean that they are not still there. Bed bugs are rarely seen in the day, out in the open or on the surface of beds or chairs. They have been described as champions of hide-and-seek. So, it is not uncommon to miss the bed bugs altogether. Bed bugs love to hide in the cracks and crevices associated with mattresses, cushions, bed frames and other structures, which is why it is very important to look for telltale symptoms of bed bugs and signs of an infestation, such as shed skins and specks of blood or feces on linens, furniture, mattresses and other areas where the bugs might be hiding.
Most bites will have a small clear area in the center surrounded by redness that may or may not be raised. People tend to become more sensitive and have larger reactions after each episode. Reactions can include itch, swelling, rash and wheals (large round red area on the skin). Severe reactions can cause skin blisters and trouble breathing, although these reactions are very rare. 
Bedbugs reproduce by a gruesome strategy appropriately named "traumatic insemination," in which the male stabs the female's abdomen and injects sperm into the wound. During their life cycle, females can lay more than 200 eggs, which hatch and go through five immature "nymph" stages before reaching their adult form, molting after each phase. [Infographic: Bedbugs: The Life of a Mini-Monster]

Bed bugs can exist singly, but tend to congregate once established. Although strictly parasitic, they spend only a tiny fraction of their lifecycles physically attached to hosts. Once a bed bug finishes feeding, it relocates to a place close to a known host, commonly in or near beds or couches in clusters of adults, juveniles, and eggs—which entomologists call harborage areas or simply harborages to which the insect returns after future feedings by following chemical trails. These places can vary greatly in format, including luggage, inside of vehicles, within furniture, among bedside clutter—even inside electrical sockets and nearby laptop computers. Bed bugs may also nest near animals that have nested within a dwelling, such as bats, birds,[22] or rodents. They are also capable of surviving on domestic cats and dogs, though humans are the preferred host of C. lectularius.[25]
Bedbugs are obligate blood parasites that belong to the insect family Cimicidae. Cimex lectularius and Cimex hemipterus, the two bedbug species that feed primarily on humans, are oval, reddish-brown, flat, and wingless. Adults are typically 4 to 7 mm in length (Figure 1). Nymphs can be as small as 1 mm, and are translucent and lighter in color 5,7 (Figure 2). Adult females produce 200 to 500 eggs in a typical six- to 12-month life span.5,8 Bedbugs can withstand temperatures from 44.6°F to 113°F (7°C to 45°C).8

Zonalon and Prudoxin (doxepin) are topical creams that can be prescribed for relief from itching. The active ingredient in these products is a topical tricyclic antidepressant and seems to work against itching by reducing histamine. Histamines are chemicals your body produces in response to injury or when having an allergic reaction. A prescription-strength cortisone cream may also help. In some cases, a prescription antihistamine will be given. 

Some people develop allergic reactions to bedbug bites, which can include a fever, difficulty breathing, hives, or a swollen tongue. Others may develop an infection where the bite starts oozing pus. If you experience either of these reactions or you develop blisters where the bites occurred, it’s a good idea to make an appointment with a dermatologist.


"We originally thought the bedbugs might prefer red because blood is red and that's what they feed on," study co-author Corraine McNeill, an assistant professor of biology at Union College in Lincoln, Nebraska, said in a statement. "However, after doing the study, the main reason we think they preferred red colors is because bedbugs themselves appear red, so they go to these harborages because they want to be with other bedbugs, as they are known to exist in aggregations."
The creatures don't have wings and they can't fly or jump. But their narrow body shape and ability to live for months without food make them ready stowaways and squatters. Bedbugs can easily hide in the seams and folds of luggage, bags and clothes. They also take shelter behind wallpaper and inside bedding, box springs and furniture. The ones that feed on people can crawl more than 100 feet (30 meters) in a night, but typically creep to within 8 feet (2.4 m) of the spot its human hosts sleep, according to the CDC.
All my life i’ve been allergic to basically everything i thought it was a normal allergic reaction…when i went to the doctors she told me it looks like a random bug bite not a bed bug bite but i didn’t believe her she sent me home with some cream and steroids for the swolleness…but why i think most doctors lie to u idk because i google’d the cream she gave me it was for scabies {so that means i got bit by a begbug and didn’t even know} not even a doctor knows half of the times what are things…thank god i read up and treated my self for bedbugs!
Bed bugs are very resilient. Nymphs and adults can persist months without feeding which is unusual for most insects. The ability to survive without a blood meal is longer at cooler temperatures ― potentially up to a year or longer at 55°F or less. In temperature-controlled buildings, a more typical duration is about 2 to 6 months. Consequently, it is usually impractical to leave buildings unoccupied in hopes of ‘starving out’ an infestation. When infested dwellings such as apartments are vacated, bed bugs often disperse to nearby units, or reduce their activity until the unit is reoccupied. 
Both of these types of Hemiptera are sensitive to extreme temperatures. It may be necessary to rid the infestation by exposing the area to extreme heat or cold; they are most comfortable in temperatures around eighty degrees Fahrenheit. Raising the temperature to ninety-seven to ninety-nine degrees may kill off a significant portion of the population.

My husband returned from a Military Deployment…and brought bed bugs home with him. The day after we realized we had them, an exterminator that specializes in Bed Bugs came to our house and sprayed. They scheduled themselves to come back in 14 days to spray again (to kill the new bugs that hatch after the initial spray). We were old the spray would kill all the adults and babies…and the second spray would get the new hatchlings. 3 days after the initial spray, we started seeing adult bugs again!
Hi Samantha! I highly recommend spending about 15min to investigate your bed (especially on the corners and don’t forget to look under the sheets, etc). If there are no signs of bed bugs, then I suggest that you don’t worry about it. Additionally, I have had itchy bites after a nights sleep and it turned out to be a once off occurrence, so just take action if it keeps happening. Hope that helps, sorry for the delayed response.
My husband and I recently stayed at a Scottish Inn, off I-75 in Florida, on our way back from NJ. We needed a room on the first floor. The only thing they had was a $32.00 room + tax. Since we were tired from driving, we took it. During the night, I woke up and I felt like something had bitten me. When we got up to get ready to leave, I noticed both my arms, left leg, one on my face, left ear and one bite on my neck had been bitten. I immediately took a hot bath, but I still can’t stop itching. I’ve never had bed bug bites before so I visited this site. I definitely will be trying the baking soda and water mix. My husband has two bites on his arm, but they’re not as bad as mine. He thinks he received them at the prior motel we stayed at.
Apply as a coarse, low-pressure spray to harborage areas including crevices, baseboards, loose plaster, behind bed frames and headboards, beneath beds and furniture, and to bedsprings and bed frames. After removal of bed linens, apply Transport Mikron to mattress and boxsprings. Apply to tufts, edges, seams and folds (do not spray clothes or bed linens). Your may apply it to furniture, but not to areas where there is direct access to seating or arm placements. Infested bed linens should not be treated, but should be removed, placed in sealed plastic bags, and taken for laundering and drying at high temperatures.
Some bed bug species are parasites of bats or birds, and may bite people if the wild hosts are no longer available. Although similar in overall appearance, the species of bed bugs that normally feed on bats, swallows, chimney swifts, pigeons or other wild hosts can be differentiated from those that prefer humans. Entomologists and knowledgeable pest managers can make this determination. If bat bugs or bird bugs are present, roosting and nesting sites should be the primary focus, and the animals should be removed and excluded from the building. 

I know this is a few years late, but I just wanted to let you know we had a similar situation, but it was for a few months every summer. Turns out there were bats in our attic, and the bat bugs will still bite you like bed bugs except they don’t really love humans so it will be infrequent and you won’t have to worry about an infestation! When you get rid of the bats, they go away eventually.
Some people have no reaction whatsoever to bed bugs. In addition to not having much of an effect on the elderly, some are just not allergic. Since the irritation and welting appears as the result of an allergic reaction, it is possible to not even know that you were bitten at all. It is entirely possible for several people to live in the same house, and have one person not be affected.
There are thousands of types of spiders (technically arachnids and not insects) crawling around the U.S., but only two of them–the black widow and the brown recluse–can cause serious problems, and even those are rare. Most of the time you’ll see red bumps that hurt and itch if you’re bitten by a spider. Very few people get the severe pain and cramping of a widow bite or the decaying ulcers of a recluse bite (although if you do, get medical help right away).

Bedbugs can live in any area of the home and use tiny cracks in furniture as well as on textiles and upholstered furniture as hiding places. They tend to be most common in areas where people sleep and generally concentrate in beds, including mattresses or mattress covers, box springs, and bed frames. They do not infest the sleeping surfaces of beds as commonly as cracks and crevices associated with the bed frame and mattress. Other sites where bedbugs often reside include curtains, edges of carpet, corners inside dressers and other furniture, cracks in wallpaper (particularly near the bed), and inside the spaces of wicker furniture.


Just recently had my first experience w/ bedbug bites in Nicaragua. Hundred plus bites in one night and over a period of three days they became so inflamed, there were tiny blisters on each bite. These suckers snacked on me like I was an all you can eat buffet. I itched 4 days straight and finally went to a pharmacy there, which prescribed me acne creme. Worked, I guess, at least psychologically. But the bites kept festering more and more.
To treat an allergic reaction, the doctor may prescribe an antihistamine, corticosteroid, or epinephrine injection. If the area is infected, he or she might prescribe an antibiotic or recommend an over-the-counter antiseptic. Finally, if it’s severe itchiness that you’re dealing with, applying corticosteroid or taking an antihistamine in pill or liquid form may be able to help.
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