As bed bugs grow they molt, shedding their skin five times before reaching maturity. A blood meal is needed between each successive molt. Adult females also must feed in order to lay eggs. Under favorable conditions (70-80°F), the bugs can mature fully in as little as a month, producing multiple generations per year. Cooler temperatures or limited access to blood prolong the development time. 
Don’t forget that in some cases a person does not react to bed bug bites at all. It’s really not that easy to easily identify bed bug bites. Often a diagnosis of spider bite is given when the person really doesn’t know what is causing the lesion(s). Spider bites are often an over diagnosed condition. Also, a hot or warm dryer is much more useful than washing clothes in hot water. Certain studies have shown that some bed bugs will withstand the wash, but not the dryer.
Some people experience anxiety, sleeplessness and unease as symptoms of having had bed bugs. Let's face it, bed bug infestations are understandably significant psychosocial stressors, and some people may experience sleeplessness as they worry about bugs biting them or their family members. Not surprisingly, people have been known to self-isolate, avoiding family and friends out of concern for spreading the infestation, or (if word gets out that they have bed bugs) they may be avoided by friends or others in the community, or find they have problems at work.  As a result, victims of bed bug infestations may experience moderate to severe levels of stress, anxiety and depression. In severe cases, these persons should seek counseling and treatment as required.

Excessively scratching the itchy, bitten areas also may increase the chance of a secondary skin infection. Antiseptic creams or lotions can be used to ward off infection and antihistamines can be used to treat the itching. And an infestation can take a psychological toll on those affected: People whose homes have been infested with bedbugs may have trouble sleeping for fear of being bitten in the night. There are also public health, social and economic consequences; office buildings and schools often have to close if they are dealing with a bedbug infestation.
Blood spots found on one’s sheets, bites and the presence of bed bug feces and cast skins are some of the indications of a bed bug infestation. Bites are commonly found on the parts of the body that are more likely to be exposed to bed bugs during sleep – the hands, neck, face, shoulders, legs and arms. While not always the case, bed bug bites are often grouped together in a small area and at times may occur in a line or a zigzag pattern. Bites normally look like small, flat or raised areas that may become inflamed, itchy, red or blistered. Bed bug bite reactions don’t always appear immediately after you’re bitten and may take a few days to begin causing symptoms. However, not everyone reacts to bed bug bites in the same manner.
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